In vivo CEST MR imaging of U87 mice brain tumor angiogenesis using targeted LipoCEST contrast agent at 7 T

2012 ◽  
Vol 69 (1) ◽  
pp. 179-187 ◽  
Author(s):  
Julien Flament ◽  
Françoise Geffroy ◽  
Christelle Medina ◽  
Caroline Robic ◽  
Jean-François Mayer ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Mr Imaging ◽  
Contrast Agent ◽  
Tumor Angiogenesis ◽  
Mice Brain

19F molecular MR imaging for detection of brain tumor angiogenesis: in vivo validation using targeted PFOB nanoparticles

Angiogenesis ◽  
2012 ◽  
Vol 16 (1) ◽  
pp. 171-179 ◽  
Author(s):  
Céline Giraudeau ◽  
Françoise Geffroy ◽  
Sébastien Mériaux ◽  
Fawzi Boumezbeur ◽  
Philippe Robert ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Mr Imaging ◽  
Tumor Angiogenesis ◽  
In Vivo Validation

In vivo monitoring of tumor angiogenesis with MR imaging

2000 ◽  
Vol 7 (10) ◽  
pp. 812-823 ◽  
Author(s):  
Robert C. Brasch ◽  
King C.P. Li ◽  
Janet E. Husband ◽  
Mary T. Keogan ◽  
Michal Neeman ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Tumor Angiogenesis ◽  
In Vivo Monitoring

Liquid oral magnetic particles as a gastrointestinal contrast agent for MR imaging: Efficacy in vivo

1993 ◽  
Vol 3 (1) ◽  
pp. 113-118 ◽  
Author(s):  
Daniel L Rubin ◽  
Holde H. Muller ◽  
Manrita K. Sidhu ◽  
Stuart W. Young ◽  
William A. Hunke ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Contrast Agent ◽  
Magnetic Particles

scholarly journals RGD-Targeted Ultrasound Contrast Agent for Longitudinal Assessment of Hep-2 Tumor Angiogenesis In Vivo

PLoS ONE ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e0149075 ◽  
Author(s):  
Qiao Hu ◽  
Xiao-Yan Wang ◽  
Li-Ke Kang ◽  
Hai-Ming Wei ◽  
Chun-Mei Xu ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Tumor Angiogenesis ◽  
Ultrasound Contrast Agent ◽  
Longitudinal Assessment ◽  
Ultrasound Contrast ◽  
Targeted Ultrasound

scholarly journals Uniform Fe3O4/Gd2O3-DHCA nanocubes for dual-mode MR imaging

2020 ◽  
Author(s):  
Miao Qin ◽  
Yueyou Peng ◽  
Mengjie Xu ◽  
Hui Yan ◽  
Yizhu Cheng ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Mr Imaging ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Clinical Diagnosis ◽  
Multimodal Imaging ◽  
Experimental Results ◽  
Dual Mode ◽  
3.0 T

Multimodal imaging technology were extensively studied over past few years, because they offered complementary diagnosis information, which can increase the accuracy of diagnosis. The synthesis of contrast agents via simplified methods are desired for the development of multimodal imaging. Herein, uniformly distributed Fe3O4/Gd2O3 nanocubes for T1-T2 dual-mode contrast agents were rationally designed and successfully fabricated by our group. In this system, the Fe3O4/Gd2O3 nanocubes were coated with nontoxic 3,4-dihydroxyhydrocinnamic acid (DHCA) for better hydrophilia and biocompatibility. The results show that Ferrum (Fe) and Gadolinium (Gd) elements are homo-dispersity in the Fe3O4/Gd2O3-DHCA (FGDA) nanocubes. Relaxivity study at 3.0 T scanner demonstrates that the r1 value and r2 value of FGDA nanocubes reach up to 67.57 ± 6.2 mM-1s-1 and 24.2 ± 1.46 mM-1s-1. The images of T1-weighted and T2-weighted imaging in vivo demonstrate that FGDA nanocubes possess the ability of magnetic resonance (MR) imaging enhancement as dual-mode contrast agent. The above illustrated experimental results indicate that FGDA nanocubes can be applied in clinical diagnosis in future.

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