Preliminary results of three protocols for the treatment of acute lymphoid leukaemia of children: Distinction of two groups of patients according to predictable prognosis

1978 ◽  
Vol 4 (1) ◽  
pp. 17-27 ◽  
Author(s):  
G. Mathé ◽  
F. de Vassal ◽  
L. Schwarzenberg ◽  
M. DeLgado ◽  
R. Weiner ◽  
...  
Keyword(s):  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia ◽  
Preliminary Results

scholarly journals A CASE OF ACUTE LYMPHOID LEUKÆMIA.

The Lancet ◽  
1918 ◽  
Vol 191 (4945) ◽  
pp. 803
Author(s):  
JohnC. Tull
Keyword(s):  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia

scholarly journals Genetic polymorphisms of Th2 interleukins, history of asthma or eczema and childhood acute lymphoid leukaemia: Findings from the ESCALE study (SFCE)

2018 ◽  
Vol 55 ◽  
pp. 96-103 ◽  
Author(s):  
A. Bonaventure ◽  
L. Orsi ◽  
J. Rudant ◽  
S. Goujon-Bellec ◽  
G. Leverger ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia ◽  
History Of

New Results of Active Immunotherapy of Acute Lymphoid Leukaemia

2015 ◽  
pp. 1115-1124
Author(s):  
G. Math� ◽  
P. Pouillart ◽  
L. Schwarzenberg ◽  
J. L. Amiel ◽  
M. Schneider ◽  
...  
Keyword(s):  
Active Immunotherapy ◽  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia

Urinary level of nickel and acute leukaemia in Chinese children

2008 ◽  
Vol 24 (9) ◽  
pp. 603-610 ◽  
Author(s):  
Y Yang ◽  
XM Jin ◽  
CH Yan ◽  
Y Tian ◽  
JY Tang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Acute Leukaemia ◽  
Oxidative Dna Damage ◽  
Metal Exposure ◽  
Etiologic Factor ◽  
Childhood Leukaemia ◽  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia ◽  
Increased Risk ◽  
Acute Myeloid

The 8-hydroxy-2′-deoxyguanosine (8-OHdG), an oxidized nucleoside of DNA, not only is a widely used biomarker for the measurement of endogenous oxidative DNA damage but might also be a risk factor for many diseases including cancer. Metal exposure may play an important role in oxidative DNA damage among children. However, few studies on urinary 8-OHdG and metals have been conducted in children with acute leukemia. In the present study, urinary Ni and 8-OHdG were examined in 116 children with acute leukaemia (94 acute lymphoid leukaemia [ALL] and 22 acute myeloid leukaemia [AML]) and 51 healthy child controls. Our result showed that urinary Ni in acute leukaemia patients (ALL: 68.40 ± 133.98, AML: 41.48 ± 76.31 ng/mg creatinine) was significantly higher than that in controls (62.47 ± 124.90 vs 17.63 ± 46.17 ng/mg creatinine, P < 0.05). Similarly, the pretherapy level of urinary 8-OHdG in patients (ALL: 11.83 ± 16.23, AML: 12.36 ± 11.36 ng/mg creatinine) was significantly elevated compared with controls (11.92 ± 15.42 vs 4.03 ± 4.70 ng/mg creatinine, P < 0.05). Moreover, urinary 8-OHdG and urinary Ni showed a weak but significant association with increased risk of childhood leukaemia. The present study suggests that Ni may be an etiologic factor for childhood acute leukaemia by oxidative DNA damage.

Dose increase of imatinib mesylate may overcome acquired resistance in bcr/abl-positive acute lymphoid leukaemia

2004 ◽  
Vol 72 (4) ◽  
pp. 302-303 ◽  
Author(s):  
Pier Paolo Piccaluga ◽  
Michele Malagola ◽  
Michela Rondoni ◽  
Marilina Amabile ◽  
Stefania Paolini ◽  
...  
Keyword(s):  
Imatinib Mesylate ◽  
Acquired Resistance ◽  
Dose Increase ◽  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia

A novel acute lymphoid leukaemia type BCR/ABL transcript in chronic myelogenous leukaemia

1997 ◽  
Vol 96 (3) ◽  
pp. 611-613 ◽  
Author(s):  
Kiyoshi Okamoto ◽  
Masamitsu Karasawa ◽  
Hirotaka Sakai ◽  
Hidemi Ogura ◽  
Kimio Morita ◽  
...  
Keyword(s):  
Chronic Myelogenous Leukaemia ◽  
Myelogenous Leukaemia ◽  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia

scholarly journals Alemtuzumab in the treatment of relapsed acute lymphoid leukaemia

Leukemia ◽  
2004 ◽  
Vol 19 (1) ◽  
pp. 135-135 ◽  
Author(s):  
P P Piccaluga ◽  
G Martinelli ◽  
M Malagola ◽  
M Rondoni ◽  
F Bonifazi ◽  
...  
Keyword(s):  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia

Blast Crisis of Chronic Myeloid Leukaemia (CML): I. PRESENTATION SIMULATING ACUTE LYMPHOID LEUKAEMIA (ALL)

1976 ◽  
Vol 34 (2) ◽  
pp. 167-178 ◽  
Author(s):  
M. E. J. Beard ◽  
Jill Durrant ◽  
D. Catovsky ◽  
E. Wiltshaw ◽  
J. L. Amess ◽  
...  
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Blast Crisis ◽  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia

scholarly journals Abnormalities in the erythrocyte membrane in acute lymphoid leukaemia

1989 ◽  
Vol 258 (3) ◽  
pp. 903-906 ◽  
Author(s):  
M Kundu ◽  
J Basu ◽  
P Chakrabarti ◽  
M M Rakshit
Keyword(s):  
Spatial Distribution ◽  
Membrane Fluidity ◽  
Erythrocyte Membrane ◽  
Severe Anaemia ◽  
Lymphoid Leukaemia ◽  
Acute Lymphoid Leukaemia ◽  
First Report

Erythrocytes from patients suffering from acute lymphoid leukaemia (ALL) show decreased proportions of spectrin tetrameters and altered spatial distribution of band 4.1 and ankyrins. These abnormalities of the cytoskeleton are probably responsible for altered membrane fluidity and transbilayer distribution of phosphatidylethanolamine in ALL. ALL is associated with severe anaemia and usually, but not always, with overproduction of lymphocytes. To our knowledge, this is the first report of abnormalities in the erythrocyte membrane in ALL which may, in part, be responsible for the observed anaemia.

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