PEO-b-PCL Block Copolymers: Synthesis, Detailed Characterization, and Selected Micellar Drug Encapsulation Behavior

2005 ◽  
Vol 26 (24) ◽  
pp. 1918-1924 ◽  
Author(s):  
Michael A. R. Meier ◽  
Sebastianus N. H. Aerts ◽  
Bastiaan B. P. Staal ◽  
Mircea Rasa ◽  
Ulrich S. Schubert
Keyword(s):  
Block Copolymers ◽  
Detailed Characterization ◽  
Drug Encapsulation

scholarly journals Amphiphilic block copolymers from a renewable ε-decalactone monomer: prediction and characterization of micellar core effects on drug encapsulation and release

2016 ◽  
Vol 4 (44) ◽  
pp. 7119-7129 ◽  
Author(s):  
Deepak Kakde ◽  
Vincenzo Taresco ◽  
Kuldeep K. Bansal ◽  
E. Peter Magennis ◽  
Steven M. Howdle ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Amphiphilic Block Copolymers ◽  
Drug Encapsulation ◽  
Micellar Core

Block co-polymers with a block derived from a sustainable monomer source are used to encapsulate and release the drug indomethacin.

PEG coated vesicles from mixtures of Pluronic P123 and l-α-phosphatidylcholine: structure, rheology and curcumin encapsulation

2017 ◽  
Vol 19 (39) ◽  
pp. 26821-26832 ◽  
Author(s):  
Bijaideep Dutta ◽  
K. C. Barick ◽  
Gunjan Verma ◽  
V. K. Aswal ◽  
Inbar Freilich ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Coated Vesicles ◽  
Drug Encapsulation ◽  
Pluronic P123

PEGylated vesicles from co-assembly of block copolymers and lipids for drug encapsulation.

Block copolymers containing dextran and deoxycholic acid polyesters. Synthesis, self-assembly and hydrophobic drug encapsulation

2019 ◽  
Vol 223 ◽  
pp. 115118 ◽  
Author(s):  
Magdalena C. Stanciu ◽  
Marieta Nichifor ◽  
Georgeta Mocanu ◽  
Cristina Tuchilus ◽  
Gabriela L. Ailiesei
Keyword(s):  
Block Copolymers ◽  
Self Assembly ◽  
Deoxycholic Acid ◽  
Hydrophobic Drug ◽  
Drug Encapsulation

Biodegradable paclitaxel-loaded microparticles prepared from novel block copolymers: influence of polymer composition on drug encapsulation and release

2013 ◽  
Vol 19 (4) ◽  
pp. 205-213 ◽  
Author(s):  
Susanna Sartori ◽  
Andrea Caporale ◽  
Alfonsina Rechichi ◽  
Domenico Cufari ◽  
Caterina Cristallini ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Polymer Composition ◽  
Drug Encapsulation

Polymersomes from Dual Responsive Block Copolymers: Drug Encapsulation by Heating and Acid-Triggered Release

2013 ◽  
Vol 14 (5) ◽  
pp. 1555-1563 ◽  
Author(s):  
Zeng-Ying Qiao ◽  
Ran Ji ◽  
Xiao-Nan Huang ◽  
Fu-Sheng Du ◽  
Rui Zhang ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Triggered Release ◽  
Drug Encapsulation ◽  
Dual Responsive

Toward quantitative defect analysis using HREM

1994 ◽  
Vol 52 ◽  
pp. 714-715
Author(s):  
David J. Smith
Keyword(s):  
Electron Microscope ◽  
Unit Cell ◽  
Defect Analysis ◽  
Significant Progress ◽  
Detailed Characterization ◽  
Small Unit ◽  
Resolution Electron ◽  
High Resolution Electron Microscope ◽  
Large Unit Cell ◽  
Made In

The electron microscope has evolved to the level where it is now straightforward to record highresolution images from thin samples (t∼10 to 20nm) that are directly interpretable in terms of atomic arrangements. Whilst recorded images necessarily represent two-dimensional projections of the structure, many defects such as dislocations and interfaces may be linear or planar in nature and thus might be expected to be amenable to detailed characterization. In this review, we briefly consider the recent significant progress that has been made in quantitative defect analysis using the high-resolution electron microscope and then discuss some drawbacks to the technique as well as potential scope for further improvements. Surveys of defect modelling for some small-unit-cell materials and interfaces have recently been published, and reference should be made to other papers in this symposium for further examples.The technique of structure imaging originated in the early '70s with observations of large-unit-cell block oxides.

Self-Assembly of Hydrogels From Elastin-Mimetic Block Copolymers

2002 ◽  
Vol 724 ◽  
Author(s):  
Elizabeth R. Wright ◽  
R. Andrew McMillan ◽  
Alan Cooper ◽  
Robert P. Apkarian ◽  
Vincent P. Conticello
Keyword(s):  
Block Copolymers ◽  
Self Assembly ◽  
Triblock Copolymers ◽  
Variable Temperature ◽  
Inverse Temperature ◽  
Temperature Transition ◽  
Scanning Calorimetry ◽  
Design Synthesis ◽  
Inverse Temperature Transition ◽  
Functional Biomaterials

AbstractTriblock copolymers have traditionally been synthesized with conventional organic components. However, triblock copolymers could be synthesized by the incorporation of two incompatible protein-based polymers. The polypeptides would differ in their hydrophobicity and confer unique physiochemical properties to the resultant materials. One protein-based polymer, based on a sequence of native elastin, that has been utilized in the synthesis of biomaterials is poly (Valine-Proline-Glycine-ValineGlycine) or poly(VPGVG) [1]. This polypeptide has been shown to have an inverse temperature transition that can be adjusted by non-conservative amino acid substitutions in the fourth position [2]. By combining polypeptide blocks with different inverse temperature transition values due to hydrophobicity differences, we expect to produce amphiphilic polypeptides capable of self-assembly into hydrogels. Our research examines the design, synthesis and characterization of elastin-mimetic block copolymers as functional biomaterials. The methods that are used for the characterization include variable temperature 1D and 2D High-Resolution-NMR, cryo-High Resolutions Scanning Electron Microscopy and Differential Scanning Calorimetry.

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