Injectable In Situ Forming Hybrid Iron Oxide-Hyaluronic Acid Hydrogel for Magnetic Resonance Imaging and Drug Delivery

2014 ◽  
Vol 14 (9) ◽  
pp. 1249-1259 ◽  
Author(s):  
Yu Zhang ◽  
Yi Sun ◽  
Xia Yang ◽  
Jöns Hilborn ◽  
Arend Heerschap ◽  
...  
2014 ◽  
Vol 110 ◽  
pp. 95-99 ◽  
Author(s):  
Xia Yang ◽  
Yi Sun ◽  
Sujit Kootala ◽  
Jöns Hilborn ◽  
Arend Heerschap ◽  
...  

2016 ◽  
Vol 40 (11) ◽  
pp. 9507-9519 ◽  
Author(s):  
Ekta Shah ◽  
Pratik Upadhyay ◽  
Mala Singh ◽  
Mohmmad Shoab Mansuri ◽  
Rasheedunnisa Begum ◽  
...  

This study shows that multiple functionalities like drug delivery and T1–T2 dual modalities can be achieved by a proper surface architecture.


RSC Advances ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 6581-6589 ◽  
Author(s):  
Fangpeng Shu ◽  
Daojun Lv ◽  
Xian-Lu Song ◽  
Bin Huang ◽  
Chong Wang ◽  
...  

DOX-doped MOF nanoparticles were prepared via a one-pot reaction and successively anchored with Fe3+ and HA for simultaneous targeted drug delivery and MR imaging.


2020 ◽  
Vol 2 (11) ◽  
pp. 5296-5304
Author(s):  
Hui Zhang ◽  
Jianping Zhang ◽  
Qianqian Zhang ◽  
Xiaofeng Liu ◽  
Yongtai Yang ◽  
...  

Inspired by the phenomenon of uniovular twins in nature, dual-Fe nanoparticles functionalized ordered mesoporous carbon have been one-pot facilely prepared, achieving the synergistic intergration of MRI effects with drug delivery property.


Nanoscale ◽  
2018 ◽  
Vol 10 (46) ◽  
pp. 21634-21639 ◽  
Author(s):  
Ye Yuan ◽  
Yixuan He ◽  
Ruonan Bo ◽  
Zhao Ma ◽  
Zhongling Wang ◽  
...  

A novel and facile approach to perform surface modification of superparamagnetic iron oxide (SPIO) with large amounts of drug loaded was presented, which can not only improve the drug efficacy, but also enable to visualize themselves by magnetic resonance imaging (MRI).


2020 ◽  
Vol 11 (2) ◽  
pp. 8654-8668

Superparamagnetic nanoparticles contain unique magnetic properties that differ from the bulk materials and are able to function at a cellular level due to their size, shape, and surface characteristics. These features make them attractive candidates for drug delivery systems, thermal mediators in hyperthermia, and magnetic resonance imaging (MRI) contrast agents. This review provides an up-to-date overview of the application of iron oxide nanoparticles in cancer diagnosis, drug delivery, treatment, and safety concerns related to these materials are considered, as well. Furthermore, the general principles and challenges of the magnetic behavior of nanoparticles in the field of oncology are also discussed. Firstly, the basic requirements for magnetic nanoparticles for biomedical applications are outlined. The close link between structure, shape, size, and magnetic characterization are described, which is considered essential for non-invasive imaging modality, innovative magnetic-driven nanocarriers, and treatment based on the overheating. In conclusion, investigation of the toxicity profile of novel nanoparticles is provided, as well. In the current review, the attention is focused on the role of magnetic nanoparticles, especially iron oxide nanoparticles in some bioapplications such as magnetic resonance imaging (MRI) contrast agents, targeted drug delivery, and magnetic hyperthermia systems.


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