Superparamagnetic iron-oxide drug-loading microbubbles for concurrent magnetic resonance imaging monitoring and focused-ultrasound enhanced brain-tumor drug delivery

Author(s):  
Ching-Hsiang Fan ◽  
Han-Jung Lin ◽  
Chien-Yu Ting ◽  
Hao-Li Liu ◽  
Tzu-Chen Yen ◽  
...  
Nanoscale ◽  
2018 ◽  
Vol 10 (46) ◽  
pp. 21634-21639 ◽  
Author(s):  
Ye Yuan ◽  
Yixuan He ◽  
Ruonan Bo ◽  
Zhao Ma ◽  
Zhongling Wang ◽  
...  

A novel and facile approach to perform surface modification of superparamagnetic iron oxide (SPIO) with large amounts of drug loaded was presented, which can not only improve the drug efficacy, but also enable to visualize themselves by magnetic resonance imaging (MRI).


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