Biocompatible Poly(L-lactide)/MWCNT Nanocomposites: Morphological Characterization, Electrical Properties, and Stem Cell Interaction

2012 ◽  
Vol 12 (7) ◽  
pp. 870-881 ◽  
Author(s):  
Erlantz Lizundia ◽  
Jòsè Ramon Sarasua ◽  
Francesco D'Angelo ◽  
Aldo Orlacchio ◽  
Sabata Martino ◽  
...  
Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1556
Author(s):  
Ivan C. C. Assunção ◽  
Susana Sério ◽  
Quirina Ferreira ◽  
Nykola C. Jones ◽  
Søren V. Hoffmann ◽  
...  

Layer-by-layer films of poly (allylamine hydrochloride) (PAH) and graphene oxide (GO) were characterized, looking at growth with the number of bilayers, morphology, and electrical properties. The PAH/GO films revealed a linear increase in absorbance with the increase in the number of deposited bilayers, allowing the determination that 10.7 ± 0.1 mg m−2 of GO is adsorbed per unit of area of each bilayer. GO absorption bands at 146, 210, 247 and 299 nm, assigned to π-π* and n-π* transitions in the aromatic ring (phenol) and of the carboxylic group, respectively, were characterized by vacuum ultraviolet spectroscopy. The morphological characterization of these films demonstrated that they are not completely uniform, with a bilayer thickness of 10.5 ± 0.7 nm. This study also revealed that the films are composed of GO and/or PAH/GO fibers and that GO is completely adsorbed on top of PAH. The electrical properties of the films reveal that PAH/GO films present a semiconductor behavior. In addition, a slight decrease in conduction was observed when films were prepared in the presence of visible light, likely due to the presence of oxygen and moisture that contributes to the damage of GO molecules.


2017 ◽  
Vol 23 (23-24) ◽  
pp. 1423-1435 ◽  
Author(s):  
Gloria Belén Ramírez-Rodríguez ◽  
Monica Montesi ◽  
Silvia Panseri ◽  
Simone Sprio ◽  
Anna Tampieri ◽  
...  

2008 ◽  
Vol 213 (5) ◽  
pp. 520-530 ◽  
Author(s):  
G. Pasquinelli ◽  
C. Orrico ◽  
L. Foroni ◽  
F. Bonafè ◽  
M. Carboni ◽  
...  

Author(s):  
Ross Ka-Kit Leung ◽  
Yixin Lin ◽  
Yanhui Liu

Abstract Intrauterine adhesion is a major cause of menstrual irregularities, infertility, and recurrent pregnancy losses and the progress towards its amelioration and therapy is slow and unsatisfactory. We aim to summarize and evaluate the current treatment progress and research methods for intrauterine adhesion. We conducted literature review in January 2020 by searching articles at PubMed on prevention and treatment, pathogenesis, the repair of other tissues/organs, cell plasticity, and the stem cell–related therapies for intrauterine adhesion. A total of 110 articles were selected for review. Uterine cell heterogeneity, expression profile, and cell-cell interaction were investigated based on scRNA-seq of uterus provided by Human Cell Landscape (HCL) project. Previous knowledge on intrauterine adhesion (IUA) pathogenesis was mostly derived from correlation studies by differentially expressed genes between endometrial tissue of intrauterine adhesion patients/animal models and normal endometrial tissue. Although the TGF-β1/SMAD pathway was suggested as the key driver for IUA pathogenesis, uterine cell heterogeneity and distinct expression profile among different cell types highlighted the importance of single-cell investigations. Cell-cell interaction in the uterus revealed the central hub of endothelial cells interacting with other cells, with endothelial cells in endothelial to mesenchymal transition and fibroblasts as the strongest interaction partners. The potential of stem cell–related therapies appeared promising, yet suffers from largely animal studies and nonstandard study design. The need to dissect the roles of endometrial cells, endothelial cells, and fibroblasts and their interaction is evident in order to elucidate the molecular and cellular mechanisms in both intrauterine adhesion pathogenesis and treatment.


Nanoscale ◽  
2020 ◽  
Vol 12 (36) ◽  
pp. 18918-18930
Author(s):  
Yoav Chemla ◽  
Efrat Shawat Avraham ◽  
Amos Markus ◽  
Eti Teblum ◽  
Aviad Slotky ◽  
...  

Carbon nanomaterials have been introduced as a scaffold for various biological applications due to their unique physical and electrical properties.


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