Functional and Highly Porous Scaffolds for Biomedical Applications

2011 ◽  
Vol 11 (10) ◽  
pp. 1432-1442 ◽  
Author(s):  
Therese Tyson ◽  
Sofia Målberg ◽  
Veronica Wåtz ◽  
Anna Finne-Wistrand ◽  
Ann-Christine Albertsson
Keyword(s):  
Biomedical Applications ◽  
Porous Scaffolds ◽  
Highly Porous

scholarly journals An overview of the effects of thermal processing on bioactive glasses

2010 ◽  
Vol 42 (3) ◽  
pp. 307-320 ◽  
Author(s):  
D. Bellucci ◽  
V. Cannillo ◽  
A. Sola
Keyword(s):  
Thermal Processing ◽  
Biomedical Applications ◽  
Soft Tissues ◽  
Glass Composition ◽  
Glass Ceramics ◽  
Point Of View ◽  
Porous Scaffolds ◽  
Bioactive Glasses ◽  
Key Factor ◽  
Highly Porous

Bioglass? 45S5 is widely used in biomedical applications due to its ability to bond to bone and even to soft tissues. The sintering ability of Bioglass? powders is a key factor from a technological point of view, since its govern the production of advanced devices, ranging from highly porous scaffolds to functionalized coatings. Unfortunately this particular glass composition is prone to crystallize at the temperature required for sintering and this may impair the bioactivity of the original glass. For these reasons, a prerequisite to tailor the fabrication of Bioglass?-derived implants is to understand the interaction between sintering, crystallization and bioactivity. In this work the structural transformations which occur during the heat treatment of Bioglass? are reviewed and a special attention is paid to the sintering and crystallization processes. Moreover the bioactivity of the final glass-ceramics is discussed and some alternative glass formulations are reported.

scholarly journals Highly porous scaffolds of PEDOT:PSS for bone tissue engineering

2017 ◽  
Vol 62 ◽  
pp. 91-101 ◽  
Author(s):  
Anne Géraldine Guex ◽  
Jennifer L. Puetzer ◽  
Astrid Armgarth ◽  
Elena Littmann ◽  
Eleni Stavrinidou ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Porous Scaffolds ◽  
Highly Porous

scholarly journals Productionof poly(L-CO-D,L LacticAcid) porous fibers by electrospinning

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Nayara Maysa da Silva Carvalho ◽  
Bárbara E. Ciocca ◽  
Rubens Maciel Filho ◽  
Marcele Fonseca Passos ◽  
Maria Regina Wolf Maciel ◽  
...  
Keyword(s):  
Pore Formation ◽  
Scientific Community ◽  
Low Dielectric Constant ◽  
Porous Scaffolds ◽  
Low Density ◽  
Fiber Morphology ◽  
Low Dielectric ◽  
Mean Diameter ◽  
Porous Fibers ◽  
Highly Porous

The production of porous scaffolds has been widely investigated by the scientific community due to its suitability for tissue engineering. Among techniques that allow the fabrication of porous materials, electrospinning is appealing for being robust and versatile. This research investigated the pore formation in poly (L-co-D,L lactic acid) fibers obtained by conventional electrospinning and the influence of chloroform as a single solvent on fiber morphology. Random and highly porous fibers with a mean diameter of 2.373 ± 0.564 µm were collected. Chloroform affects the fiber morphology, mainly for its fast evaporation and low density of charges. The solvent on the surface evaporates quickly, and the low stretch of the jet does not help the polymer to reorganize over the length of the fiber, forming pores. In conclusion, the low dielectric constant and boiling point of chloroform induce pores formation along the PLDLA fibers.  

scholarly journals Novel whey protein isolate-based highly porous scaffolds modified with therapeutic ion-releasing bioactive glasses

2020 ◽  
Vol 261 ◽  
pp. 127115 ◽  
Author(s):  
Michal Dziadek ◽  
Timothy E.L. Douglas ◽  
Kinga Dziadek ◽  
Barbara Zagrajczuk ◽  
Andrada Serafim ◽  
...  
Keyword(s):  
Whey Protein ◽  
Whey Protein Isolate ◽  
Protein Isolate ◽  
Porous Scaffolds ◽  
Bioactive Glasses ◽  
Highly Porous

Fabrication of highly porous scaffolds for tissue engineering based on star-shaped functional poly(ε-caprolactone)

2010 ◽  
Vol 108 (3) ◽  
pp. 694-703 ◽  
Author(s):  
Stefan Theiler ◽  
Petra Mela ◽  
Stefanos E. Diamantouros ◽  
Stefan Jockenhoevel ◽  
Helmut Keul ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Porous Scaffolds ◽  
Highly Porous

Carbonated-Apatite/Gelatine Porous Scaffolds for Bone Replacement

2007 ◽  
Vol 361-363 ◽  
pp. 547-550 ◽  
Author(s):  
Elena Landi ◽  
Selanna Martorana ◽  
Anna Tampieri ◽  
Stefano Guicciardi ◽  
Cesare Melandri
Keyword(s):  
Biomedical Applications ◽  
Young Modulus ◽  
Porous Scaffolds ◽  
Carbonate Apatite ◽  
Design And Synthesis ◽  
Carbonated Apatite ◽  
Bone Replacement ◽  
Compressive And Flexural Strengths ◽  
Phase Chemical

A novel foaming method of design and synthesis of porous Carbonate-apatite/gelatine composite scaffolds is proposed for biomedical applications. Two different suspensions, one constituted by a biomimetic inorganic phase (B-CHA) and the second by a protein (gelatine), are mixed, foamed, lyophilized and, in some cases, cross-linked to stabilize the organic phase. Chemical, morphological and mechanical features of the scaffolds are evaluated. The samples have chemical composition, compressive and flexural strengths and Young modulus values in the range of trabecular bone ones. A high interconnected porosity (about 90%) showing a micro- to macrosize distribution, that is needed for osteoconduction and vascolarization processes in vivo, is also detected.

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