scholarly journals Risk factors for alcohol relapse after liver transplantation for alcoholic cirrhosis in Japan

2014 ◽  
Vol 20 (3) ◽  
pp. 298-310 ◽  
Author(s):  
Hiroto Egawa ◽  
Katsuji Nishimura ◽  
Satoshi Teramukai ◽  
Masakazu Yamamoto ◽  
Koji Umeshita ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Transplantation ◽  
Alcoholic Cirrhosis ◽  
Alcohol Relapse

scholarly journals Alcoholic cirrhosis is a good indication for liver transplantation, even for cases of recidivism

Gut ◽  
1999 ◽  
Vol 45 (3) ◽  
pp. 421-426 ◽  
Author(s):  
G-P Pageaux ◽  
J Michel ◽  
V Coste ◽  
P Perney ◽  
P Possoz ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
Survival Rates ◽  
Alcoholic Cirrhosis ◽  
Immunosuppressive Regimen ◽  
Recidivism Rate ◽  
Ethical Considerations ◽  
Alcohol Relapse ◽  
Two Factors ◽  
Alcoholic Disease

BACKGROUND/AIMSAlcoholic cirrhosis remains a controversial indication for liver transplantation, mainly because of ethical considerations related to the shortage of donor livers. The aim of this study was to review experience to date, focusing on survival rates and complications, and the effect of alcohol relapse on outcome and alterations in marital and socioprofessional status.METHODSThe results for 53 patients transplanted for alcoholic cirrhosis between 1989 and 1994 were compared with those for 48 patients transplanted for non-alcoholic liver disease. The following variables were analysed: survival, rejection, infection, cancer, retransplantation, employment and marital status, alcoholic recurrence. The same variables were compared between alcohol relapsers and non-relapsers.RESULTSRecovery of employment was the only significantly different variable between alcoholic (30%) and non-alcoholic patients (60%). Two factors influenced survival in the absence of alcohol recidivism: age and abstinence before transplantation. For all other variables, there were no differences between alcoholic and non-alcoholic patients, and, within the alcoholic group, between relapsers and non-relapsers. The recidivism rate was 32%.CONCLUSIONThe data indicate that liver transplantation is justified for alcoholic cirrhosis, even in cases of recidivism, which did no affect survival and compliance with the immunosuppressive regimen. These good results should help in educating the general population about alcoholic disease.

Risk Factors for Alcohol Relapse Following Orthotopic Liver Transplantation: A Systematic Review

2015 ◽  
Vol 56 (1) ◽  
pp. 21-35 ◽  
Author(s):  
James K. Rustad ◽  
Theodore A. Stern ◽  
Maithri Prabhakar ◽  
Dominique Musselman
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Liver Transplantation ◽  
Orthotopic Liver Transplantation ◽  
Alcohol Relapse

181Carbohydrate deficient transferrin for detection of alcohol relapse following liver transplantation for alcoholic cirrhosis

2000 ◽  
Vol 6 (3) ◽  
pp. C45-C45
Author(s):  
G BERLAKOVICH ◽  
T WINDHAGER ◽  
E FREUNDORFER ◽  
O LESCH ◽  
R STEININGER ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Alcoholic Cirrhosis ◽  
Alcohol Relapse

CARBOHYDRATE DEFICIENT TRANSFERRIN FOR DETECTION OF ALCOHOL RELAPSE AFTER ORTHOTOPIC LIVER TRANSPLANTATION FOR ALCOHOLIC CIRRHOSIS

1999 ◽  
Vol 67 (9) ◽  
pp. 1231-1235 ◽  
Author(s):  
Gabriela A. Berlakovich ◽  
Thomas Windhager ◽  
Edith Freundorfer ◽  
Otto M. Lesch ◽  
Rudolf Steininger ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Orthotopic Liver Transplantation ◽  
Alcoholic Cirrhosis ◽  
Alcohol Relapse ◽  
Carbohydrate Deficient Transferrin

scholarly journals Incidence and Risk Factors of Alcohol Relapse after Liver Transplantation: Analysis of Pre-Transplant Abstinence and Psychosocial Features

2020 ◽  
Vol 9 (11) ◽  
pp. 3716
Author(s):  
Tien-Wei Yu ◽  
Yu-Ming Chen ◽  
Chih-Chi Wang ◽  
Chih-Che Lin ◽  
Kuang-Tzu Huang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Transplantation ◽  
Healthy Lifestyle ◽  
Graft Loss ◽  
Patient Centered ◽  
Alcohol Relapse ◽  
Younger Age ◽  
Liver Transplantations ◽  
Long Term Follow Up ◽  
Abstinence Period

Alcohol-associated liver disease (ALD) is a common indication for liver transplantation (LT). Alcohol relapse after LT is associated with graft loss and worse prognosis. Over the past 20 years, the number and prevalence of living donor liver transplantations (LDLTs) have increased in Taiwan. The aims of this retrospective study are to analyze the incidence and risk factors of alcohol relapse after LT at a single center in Taiwan. A total of 98 patients with ALD who underwent LT from January 2012 to December 2018 were retrospectively evaluated by chart review. Pre-transplant characteristics as well as psychosocial and alcoholic history were used to test the possible associations among the risk factors studied and post-LT alcohol relapse. The incidence of post-LT alcohol relapse was 16.3%. The median duration of alcohol relapse after liver transplantation was 28.1 months (range: 1–89.4 months). The cumulative incidence was 12% and 19% at 1 year and 3 years after LT, respectively. The most powerful risk factors were a pre-LT abstinence period less than 6 months and younger age of starting alcohol. For predicting alcohol relapse, the accuracy rate of abstinence less than 6 months was up to 83.7%. In summary, pre-abstinence period plays a role in predicting post-LT alcohol relapse. Post-LT interventions should be considered specifically for the patients with short abstinence period. Long-term follow-up, patient-centered counseling, and enhancement of healthy lifestyle are suggested to prevent alcohol relapse.

Significance of pretransplant abstinence on harmful alcohol relapse after liver transplantation for alcoholic cirrhosis in Japan

2014 ◽  
Vol 44 (14) ◽  
pp. E428-E436 ◽  
Author(s):  
Hiroto Egawa ◽  
Yoshihide Ueda ◽  
Naoki Kawagishi ◽  
Takahito Yagi ◽  
Hiroyuki Kimura ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Alcoholic Cirrhosis ◽  
Alcohol Relapse ◽  
Harmful Alcohol
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