Squamous cell carcinoma associated with intralesional injection of cidofovir for recurrent respiratory papillomatosis

2009 ◽  
Vol 119 (3) ◽  
pp. 567-570 ◽  
Author(s):  
David G. Lott ◽  
Paul R. Krakovitz
1993 ◽  
Vol 152 (9) ◽  
pp. 776-778 ◽  
Author(s):  
B. Simma ◽  
R. Burger ◽  
J. Uehlinger ◽  
D. Ghelfi ◽  
E. Hof ◽  
...  

Apmis ◽  
2015 ◽  
Vol 123 (9) ◽  
pp. 821-822 ◽  
Author(s):  
Michael Barsky ◽  
Hassan S. Moghaddas ◽  
Sarah Almubarak ◽  
Craig M. Forleiter ◽  
Adnan M. Al-Ayoubi ◽  
...  

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110546
Author(s):  
Aaron C Kovacs ◽  
Domagoj Vodanovich ◽  
Emily K Mogridge ◽  
Lisa Wun ◽  
June Corry

Recurrent respiratory papillomatosis is a human papillomavirus-mediated condition characterised by the development of benign squamous papillomata of the respiratory tract. Malignant transformation of recurrent respiratory papillomatosis, while rare, carries a poor prognosis and there are limited data surrounding treatment options, particularly in inoperable disease. We present the case of a 64-year-old male who developed malignant airway obstruction secondary to primary tracheal squamous cell carcinoma in the setting of a 5-year history of recurrent laryngotracheal papillomatosis, requiring placement of tracheostomy while on veno-venous extracorporeal membranous oxygenation. He was managed with cisplatin-based definitive chemoradiotherapy and had a complete metabolic response on post-treatment positron emission tomography/computed tomography, and remains free of recurrent squamous cell carcinoma at 16 months following treatment. This case supports the use of combined chemoradiotherapy as a potential therapeutic option for patients with primary tracheal squamous cell carcinoma, and emphasises the challenges associated with the long-term management of recurrent respiratory papillomatosis.


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