Is DSM-IV criterion A2 associated with PTSD diagnosis and symptom severity?

2012 ◽  
Vol 25 (4) ◽  
pp. 368-375 ◽  
Author(s):  
Princess E. Osei-Bonsu ◽  
Avron Spiro ◽  
Mark R. Schultz ◽  
Karen A. Ryabchenko ◽  
Eric Smith ◽  
...  
2007 ◽  
Author(s):  
Juliet Vogel ◽  
Jessica Levitt ◽  
James Rodriguez ◽  
Jameson Foster ◽  
Marleen Radigan
Keyword(s):  

2017 ◽  
Vol 205 (2) ◽  
pp. 83-86 ◽  
Author(s):  
Jeanne M.D. Jakob ◽  
Kristen Lamp ◽  
Sheila A.M. Rauch ◽  
Erin R. Smith ◽  
Katherine R. Buchholz

2009 ◽  
Vol 119 (1) ◽  
pp. 25-34 ◽  
Author(s):  
R. Yehuda ◽  
J. Schmeidler ◽  
E. Labinsky ◽  
A. Bell ◽  
A. Morris ◽  
...  

2011 ◽  
Vol 26 (S2) ◽  
pp. 71-71
Author(s):  
E. Kurgyis ◽  
B. Andó ◽  
S. Rózsa ◽  
A. Szkaliczki ◽  
I. Demeter ◽  
...  

IntroductionTemperament and character factors and specific impulse control-related personality traits are connected to the developmental and clinical aspects of alcohol use disorder (AUD).Objectives/aimsTo reveal the underlying personality structure of individual differences in the symptom severity of AUD. Therefore temperament and character, impulsivity and aggression were assessed in relation to alcohol addiction severity.MethodsSixty-three patients with AUD were involved. Temperament and Character Inventory-Revised was used to quantify temperament and character dimensions. Impulsivity was assessed by the Barratt Impulsivity Scale-11 (BIS) and aggression by the Buss-Perry Aggression Questionnaire (BPAQ). To determine symptom severity of AUD the Severity of Alcohol Dependence Questionnaire (SADQ), the Alcohol Use Disorders Identification Test (AUDIT), the MacAndrew Alcoholism Scale-Revised (MAC-R) and the number of DSM-IV alcohol dependence symptoms were registered. To analyze the connections between symptom severity indicators and personality factors Pearson and Spearman correlation analysis were applied, p < 0.05 were considered significant.ResultsSADQ (r = 0.290), AUDIT (r = 0.345), MAC-R (r = 0.504) and the DSM-IV alcohol dependence symptoms (Spearman rho = 0.271) correlated positively with novelty-seeking temperament factor. SADQ (r = 0.262) and AUDIT (r = 0.293) scores correlated positively with BIS. Furthermore SADQ (r = 0.382), AUDIT (r = 0.318), MAC-R (r = 0.416) correlated positively with BPAQ.ConclusionsNovelty-seeking, impulsivity and aggression as indicators of impulse control have different theoretical backgrounds but a common root. This study has revealed that the adverse consequences of lower impulse control can lead to more severe symptoms of AUD. These connections between impulse control and the symptomatology could contribute to a better understanding of the clinical complexity of AUD.


Author(s):  
Heike Weber ◽  
Adam X. Maihofer ◽  
Nenad Jaksic ◽  
Elma Feric Bojic ◽  
Sabina Kucukalic ◽  
...  

Abstract Objectives Posttraumatic stress disorder (PTSD) is triggered by extremely stressful environmental events and characterized by high emotional distress, re-experiencing of trauma, avoidance and hypervigilance. The present study uses polygenic risk scores (PRS) derived from the UK Biobank (UKBB) mega-cohort analysis as part of the PGC PTSD GWAS effort to determine the heritable basis of PTSD in the South Eastern Europe (SEE)-PTSD cohort. We further analyzed the relation between PRS and additional disease-related variables, such as number and intensity of life events, coping, sex and age at war on PTSD and CAPS as outcome variables. Methods Association of PRS, number and intensity of life events, coping, sex and age on PTSD were calculated using logistic regression in a total of 321 subjects with current and remitted PTSD and 337 controls previously subjected to traumatic events but not having PTSD. In addition, PRS and other disease-related variables were tested for association with PTSD symptom severity, measured by the Clinician Administrated PTSD Scale (CAPS) by liner regression. To assess the relationship between the main outcomes PTSD diagnosis and symptom severity, each of the examined variables was adjusted for all other PTSD related variables. Results The categorical analysis showed significant polygenic risk in patients with remitted PTSD and the total sample, whereas no effects were found on symptom severity. Intensity of life events as well as the individual coping style were significantly associated with PTSD diagnosis in both current and remitted cases. The dimensional analyses showed as association of war-related frequency of trauma with symptom severity, whereas the intensity of trauma yielded significant results independently of trauma timing in current PTSD. Conclusions The present PRS application in the SEE-PTSD cohort confirms modest but significant polygenic risk for PTSD diagnosis. Environmental factors, mainly the intensity of traumatic life events and negative coping strategies, yielded associations with PTSD both categorically and dimensionally with more significant p-values. This suggests that, at least in the present cohort of war-related trauma, the association of environmental factors and current individual coping strategies with PTSD psychopathology was stronger than the polygenic risk.


Author(s):  
Kelly S. Parker-Guilbert ◽  
Samantha J. Moshier ◽  
Brian P. Marx ◽  
Terence M. Keane

Assessment of post-traumatic stress disorder (PTSD) symptom severity serves a variety of important clinical and research purposes and may be able to more accurately represent the nature of posttraumatic stress when compared with traditional categorical diagnosis. Numerous measures that assess PTSD symptom severity are available and choosing measures with strong psychometric properties that meet one’s clinical or research needs is essential to accurate assessment. This task is made more complex by the recent update to the PTSD symptom criteria from DSM-IV-TR to DSM-5. This chapter discusses available clinician-rated and self-report methods for evaluating PTSD symptom severity and makes recommendations for clinicians and researchers across a range of contexts and patient populations.


2015 ◽  
Vol 7 (3) ◽  
pp. 295-302 ◽  
Author(s):  
Santiago Papini ◽  
Patricia Yoon ◽  
Mikael Rubin ◽  
Teresa Lopez-Castro ◽  
Denise A. Hien

2020 ◽  
Vol Volume 16 ◽  
pp. 43-54
Author(s):  
Yirui Hu ◽  
Xin Chu ◽  
Thomas G Urosevich ◽  
Stuart N Hoffman ◽  
H Lester Kirchner ◽  
...  

2007 ◽  
Vol 19 (1) ◽  
pp. 38-44 ◽  
Author(s):  
Lucy Tully ◽  
Gordon Parker

Objective:There has been considerable debate about the diagnostic rules for bipolar II disorder, particularly the 4-day duration criteria for hypomanic episodes. This study examined whether highs lasting minutes or hours differed from longer highs in terms of clinical features and symptom severity. It also examined whether duration of highs predicted bipolar disorder being diagnosed.Method:A total of 518 subjects with significant episodes of depression and ‘highs’ completed a web-based self-report questionnaire. Those who reported their longest highs lasting minutes or hours were compared with those who reported longer durations of highs on a range of clinical variables and measures of symptom severity.Results:Subjects whose highs lasted minutes or hours reported clinical features and severity of symptoms similar to those whose highs lasted 3–7 days. However, the odds of being diagnosed with bipolar disorder for those with highs lasting 3–7 days were almost three times higher than for those whose highs lasted minutes or hours.Conclusion:The 4-day DSM-IV minimum-duration criteria for hypomania may lead to failure to diagnose subjects with brief highs who have true bipolar disorder and thus should be reconsidered.


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