scholarly journals High throughput computational evaluation of how scaffold architecture, material selection, and loading modality influence the cellular micromechanical environment in tissue engineering strategies

JOR Spine ◽  
2021 ◽  
Author(s):  
Mitchell I. Page ◽  
Peter E. Linde ◽  
Christian M. Puttlitz
Keyword(s):  
Tissue Engineering ◽  
High Throughput ◽  
Material Selection ◽  
Computational Evaluation ◽  
Scaffold Architecture

High-throughput hyaluronic acid hydrogels array for cell selective adhesion screening

2021 ◽  
Author(s):  
Cong Wang ◽  
Hongye Hao ◽  
Jing Wang ◽  
Yunfan Xue ◽  
Jun-jie Huang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Hyaluronic Acid ◽  
High Throughput ◽  
Biomedical Field

As a component of extracellular matrix (ECM), hyaluronic acid (HA) has plenty of applications in biomedical field such as tissue engineering. Due to its non-adhesive nature, HA requires further functional...

scholarly journals Immunomodulatory Functions of Mesenchymal Stem Cells in Tissue Engineering

2019 ◽  
Vol 2019 ◽  
pp. 1-18 ◽  
Author(s):  
Haojiang Li ◽  
Shi Shen ◽  
Haitao Fu ◽  
Zhenyong Wang ◽  
Xu Li ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Tissue Regeneration ◽  
Tissue Damage ◽  
Material Selection ◽  
Immune Microenvironment ◽  
Chronic Injury ◽  
Research Fields

The inflammatory response to chronic injury affects tissue regeneration and has become an important factor influencing the prognosis of patients. In previous stem cell treatments, it was revealed that stem cells not only have the ability for direct differentiation or regeneration in chronic tissue damage but also have a regulatory effect on the immune microenvironment. Stem cells can regulate the immune microenvironment during tissue repair and provide a good “soil” for tissue regeneration. In the current study, the regulation of immune cells by mesenchymal stem cells (MSCs) in the local tissue microenvironment and the tissue damage repair mechanisms are revealed. The application of the concepts of “seed” and “soil” has opened up new research avenues for regenerative medicine. Tissue engineering (TE) technology has been used in multiple tissues and organs using its biomimetic and cellular cell abilities, and scaffolds are now seen as an important part of building seed cell microenvironments. The effect of tissue engineering techniques on stem cell immune regulation is related to the shape and structure of the scaffold, the preinflammatory microenvironment constructed by the implanted scaffold, and the material selection of the scaffold. In the application of scaffold, stem cell technology has important applications in cartilage, bone, heart, and liver and other research fields. In this review, we separately explore the mechanism of MSCs in different tissue and organs through immunoregulation for tissue regeneration and MSC combined with 3D scaffolds to promote MSC immunoregulation to repair damaged tissues.

scholarly journals High Throughput Micro-Well Generation of Hepatocyte Micro-Aggregates for Tissue Engineering

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e105171 ◽  
Author(s):  
Elien Gevaert ◽  
Laurent Dollé ◽  
Thomas Billiet ◽  
Peter Dubruel ◽  
Leo van Grunsven ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
High Throughput

scholarly journals Development of a High-Throughput Ultrasound Technique for the Analysis of Tissue Engineering Constructs

2015 ◽  
Vol 44 (3) ◽  
pp. 793-802 ◽  
Author(s):  
Jessica M. Stukel ◽  
Monika Goss ◽  
Haoyan Zhou ◽  
Wenda Zhou ◽  
Rebecca Kuntz Willits ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
High Throughput ◽  
Ultrasound Technique

scholarly journals Tissue Engineering: High-Throughput Fabrication and Modular Assembly of 3D Heterogeneous Microscale Tissues (Small 5/2017)

Small ◽  
2017 ◽  
Vol 13 (5) ◽  
Author(s):  
Wenguang Yang ◽  
Haibo Yu ◽  
Gongxin Li ◽  
Yuechao Wang ◽  
Lianqing Liu
Keyword(s):  
Tissue Engineering ◽  
High Throughput ◽  
Modular Assembly

Control and Monitoring of Scaffold Architecture for Tissue Engineering

2008 ◽  
pp. 69-94
Author(s):  
Ying Yang ◽  
Cassilda Cunha-Reis ◽  
Pierre Olivier Bagnaninchi ◽  
Halil Murat Aydin
Keyword(s):  
Tissue Engineering ◽  
Scaffold Architecture
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