In vitro inhibition of ?-chymotryptic activity by phenolic compounds

2001 ◽  
Vol 81 (15) ◽  
pp. 1512-1521 ◽  
Author(s):  
Sascha Rohn ◽  
Harshadrai M Rawel ◽  
Nadine Pietruschinski ◽  
J�rgen Kroll
Keyword(s):  
Phenolic Compounds ◽  
In Vitro Inhibition ◽  
Chymotryptic Activity

In Vitro Inhibition of Human Carbonic Anhydrase I and II Isozymes with Natural Phenolic Compounds

2011 ◽  
Vol 77 (6) ◽  
pp. 494-499 ◽  
Author(s):  
Murat Şentürk ◽  
İlhami Gülçin ◽  
Şükrü Beydemir ◽  
Ö. İrfan Küfrevioğlu ◽  
Claudiu T. Supuran
Keyword(s):  
Phenolic Compounds ◽  
Carbonic Anhydrase ◽  
Carbonic Anhydrase I ◽  
Natural Phenolic Compounds ◽  
In Vitro Inhibition ◽  
Human Carbonic Anhydrase

In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds

2011 ◽  
Vol 21 (14) ◽  
pp. 4259-4262 ◽  
Author(s):  
Sevim Beyza Öztürk Sarikaya ◽  
Fevzi Topal ◽  
Murat Şentürk ◽  
İlhami Gülçin ◽  
Claudiu T. Supuran
Keyword(s):  
Phenolic Compounds ◽  
Carbonic Anhydrase ◽  
In Vitro Inhibition

Phenolic compounds from in vitro cultures of Rindera graeca Boiss. & Feldr.

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
K Sykłowska-Baranek ◽  
A Pietrosiuk ◽  
K Graikou ◽  
H Damianakos ◽  
M Jeziorek ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
In Vitro Cultures

Inhibition by Phenol and Phenolic Acids of Platelet Release Reaction

1973 ◽  
Vol 30 (02) ◽  
pp. 334-338 ◽  
Author(s):  
Felisa C. Molinas
Keyword(s):  
Renal Failure ◽  
Phenolic Compounds ◽  
Phenolic Acids ◽  
Platelet Function ◽  
Deleterious Effect ◽  
Release Reaction ◽  
Contributory Factors ◽  
Adp Release ◽  
Platelet Release

SummaryIt has been postulated that the high phenol and phenolic acids plasmatic levels found in patients with chronic renal failure are contributory factors in the abnormal platelet function described in these patients. This hypothesis was corroborated by “in vitro” studies showing the deleterious effect of these compounds on certain platelet function after pre-incubation of PRP with phenol and phenolic compounds. The present studies were conducted to determine the influence of phenolic compounds on platelet release reaction. It was found that phenol inhibited from 62.5 to 100% the effect of the aggregating agents thrombin, adrenaline and ADP on platelet 5-HT-14C release. The phenolic acids p-, m-, and o-HPAA inhibited from 36.35 to 94.8% adrenaline and ADP-induced platelet 5-HT-14C release. Adrenaline-induced platelet ADP release was inhibited from 27.45 to 38.10% by the phenolic compounds. These findings confirm the hypothesis that phenolic compounds interfere with platelet function through the inhibition of the release reaction.

Effekte von Substanz P und Neurotensin auf die Kontraktilität des Ileums der Maus in vitro: Inhibition durch STW 5

2007 ◽  
Vol 45 (08) ◽  
Author(s):  
D Hagelauer ◽  
O Kelber ◽  
D Weiser ◽  
S Laufer ◽  
H Heinle
Keyword(s):  
Substanz P ◽  
In Vitro Inhibition
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