Capillary electrophoretic method for the simultaneous determination of nitrate, nitrite and bromate ions in some selected plants

2021 ◽  
Author(s):  
Zebron Nchimunya Tembo ◽  
Seker Fatma Aygun
Keyword(s):  
Simultaneous Determination ◽  
Electrophoretic Method ◽  
Capillary Electrophoretic

A sub-minute electrophoretic method for simultaneous determination of naphazoline and zinc

2016 ◽  
Vol 1472 ◽  
pp. 134-137 ◽  
Author(s):  
Michelle M.A.C. Ribeiro ◽  
Thiago C. Oliveira ◽  
Alex D. Batista ◽  
Rodrigo A.A. Muñoz ◽  
Eduardo M. Richter
Keyword(s):  
Simultaneous Determination ◽  
Electrophoretic Method

Capillary electrophoretic method for the determination of diterpenoid isomers in Acanthopanax species

2006 ◽  
Vol 40 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Nguyen Thi Phuong ◽  
Kyung Ah Lee ◽  
Su Jin Jeong ◽  
Cai Xing Fu ◽  
Jung Kap Choi ◽  
...  
Keyword(s):  
Electrophoretic Method ◽  
Capillary Electrophoretic ◽  
Acanthopanax Species

scholarly journals Determination of HMG-CoA reductase inhibitors by micellar electrokinetic chromatography

2016 ◽  
Vol 62 (2) ◽  
pp. 187-191 ◽  
Author(s):  
Eleonora Mircia ◽  
Gabriel Hancu ◽  
Aura Rusu ◽  
Adriana Cazacu ◽  
Teodora Balaci ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Sodium Dodecyl ◽  
Injection Pressure ◽  
Electrophoretic Method ◽  
Pharmaceutical Tablets ◽  
Reductase Inhibitors ◽  
Simultaneous Separation ◽  
Hydroxyl Acid ◽  
Coa Reductase

AbstractObjective: In this study we report the development of a simple, rapid and efficient capillary electrophoresis method for the simultaneous determination of atorvastatin, fluvastatin, lovastatin and simvastin.Methods: Capillary zone electrophoresis proved to be efficient for the simultaneous separation of atorvastatin and fluvastatin, but could not resolve the determination of lovastatin and simvastatin. The simultaneous separation of all four statins was achieved by applying a micellar electrokinetic chromatographic method, after transforming lovastatin and simvastatin in β-hydroxyl acid forms through alkaline hydrolysis. The optimum electrophoretic conditions and analytical parameters were investigated and the analytical performances of the method were verified with regard to linearity, precision, accuracy, LOD and LOQ.Results: The optimum electrophoretic separation conditions were: 25 mM sodium tetraborate with 25 mM sodium dodecyl sulphate buffer electrolyte at pH 9.5, applied voltage + 25 kV, separation temperature 25 °C, injection pressure/time 50 mbar/1 minutes, UV detection at 230 nm. Using the optimized electrophoretic conditions we succeeded in the simultaneous determination of the four statins in approximately 3 minutes, the order of migration being: atorvastatin, fluvastatin, lovastatin, simvastatin. The proposed method has been applied to the determination of the analytes in pharmaceutical tablets formulations.Conclusions: The capillary electrophoretic method developed in the present work proved to be suitable for the routine analysis of statins and can be adopted as quality control protocol in pharmaceutical analysis.

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