Strategy for improved analysis of peptides by surface-enhanced Raman spectroscopy (SERS) involving positively charged nanoparticles

2008 ◽  
Vol 39 (5) ◽  
pp. 611-617 ◽  
Author(s):  
Sarah M. Ngola ◽  
Jingwu Zhang ◽  
Breeana L. Mitchell ◽  
Narayan Sundararajan
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Charged Nanoparticles ◽  
Positively Charged

scholarly journals Sensitive and Selective Detection of New Red Colorant Based on Surface-Enhanced Raman Spectroscopy Using Molecularly Imprinted Hydrogels

2019 ◽  
Vol 9 (13) ◽  
pp. 2672 ◽  
Author(s):  
Jing Neng ◽  
Kaiyun Xu ◽  
Yan Wang ◽  
Kan Jia ◽  
Qi Zhang ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Selective Detection ◽  
Molecularly Imprinted ◽  
Au Nps ◽  
Relative Standard ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Positively Charged

A polyacrylamide-based molecularly imprinted hydrogel (MIH) doped with positively charged gold nanoparticles (Au NPs) has been synthesized via a free radical polymerization of acrylamide (AM) aqueous solution containing positively charged Au NPs as a Raman active substrate, New Red colorant as a template molecule, N,N’-methylenebis(acrylamide) as a crosslinking agent, and potassium persulfate as an initiator. The Au NPs-doped MIHs were subsequently explored as a Raman active substrate for the sensitive and selective detection of New Red colorant via surface-enhanced Raman spectroscopy (SERS). The logarithmic intensity of the characteristic peak of New Red at 1572 cm−1 was proportional to the logarithmic concentration of New Red with a detection linear range of 1.64 × 10−6 to 1.64 × 10−4 M and a limit of detection (LOD) of 1.64 × 10−7 M. The recoveries ranged from 86.3% to 100.6% with a relative standard deviation (RSD) in the range of 2.3% to 7.7%. The RSD and recovery rates for the detection of New Red spiked in a sports drink sample were 1.8% to 7.7% and 91.0% to 97.1%, respectively. These results showed that SERS combined with MIHs as Raman active substrates could provide a sensitive, selective, and effective approach for the detection of the New Red colorant in beverage matrix.

Simple preparation of positively charged silver nanoparticles for detection of anions by surface-enhanced Raman spectroscopy

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 2988-2994 ◽  
Author(s):  
A. Stewart ◽  
S. Murray ◽  
S. E. J. Bell
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Zeta Potential ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrates ◽  
Simple Preparation ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Positively Charged

Modification of Ag colloids with thiocholine bromide switches the zeta potential from ca. −50 mV to ca. +50 mV, giving SERS substrates which promote adsorption of anions.

Diethyldithiocarbamate (DDTC) induced formation of positively charged silver nanoparticles for rapid in situ identification of inorganic explosives by surface enhanced Raman spectroscopy

RSC Advances ◽  
2016 ◽  
Vol 6 (57) ◽  
pp. 51823-51829 ◽  
Author(s):  
Juan Chen ◽  
Yu-e Shi ◽  
Min Zhang ◽  
Jinhua Zhan
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Surface Enhanced Raman Spectroscopy ◽  
Raman Spectrometer ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Positively Charged ◽  
Portable Raman

Diethyldithiocarbamate could induce the generation of positively charged silver nanoparticles for rapidin situdetection of the explosives with a portable Raman spectrometer.

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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