Comparison of Aspirin and Copper Aspirinate with Respect to Gastric Mucosal Damage in the Rat

1983 ◽  
Vol 72 (12) ◽  
pp. 1457-1461 ◽  
Author(s):  
Agnes A. Alich ◽  
Victoria J. Welsh ◽  
Lorentz E. Wittmers
Keyword(s):  
Mucosal Damage ◽  
Gastric Mucosal Damage ◽  
Copper Aspirinate

Gastric mucosal damage due to aspirin and copper aspirinate assessed by gastric mucosal potential difference changes

1992 ◽  
Vol 27 (4) ◽  
pp. 245-250 ◽  
Author(s):  
A.A. Alich ◽  
L.E. Wittmers ◽  
Lee A. Anderson ◽  
Elise M. Rieschl ◽  
Patricia L. Peterson
Keyword(s):  
Mucosal Damage ◽  
Potential Difference ◽  
Gastric Mucosal Damage ◽  
Copper Aspirinate

Protective effects of ethanol extract of a Mexican propolis on indomethacin-induced gastric mucosal damage in mice.

2019 ◽  
Author(s):  
DV Pilar ◽  
VVS Ibran ◽  
RC Mario ◽  
CA Octavio ◽  
MM Canales-Martinez ◽  
...  
Keyword(s):  
Ethanol Extract ◽  
Mucosal Damage ◽  
Gastric Mucosal Damage ◽  
Protective Effects

Nonprotein sulfhydryl compounds in canine gastric mucosa: effects of PGE2 and ethanol

1985 ◽  
Vol 249 (1) ◽  
pp. G137-G144 ◽  
Author(s):  
T. A. Miller ◽  
D. Li ◽  
Y. J. Kuo ◽  
K. L. Schmidt ◽  
L. L. Shanbour
Keyword(s):  
Gastric Mucosa ◽  
Low Dose ◽  
Mucosal Damage ◽  
Gastric Mucosal Damage ◽  
High Dose ◽  
Mucosal Protection ◽  
Gastric Mucosal Protection ◽  
Sulfhydryl Compounds ◽  
Mild Irritants

By use of an in vivo canine chambered stomach preparation in which the gastric mucosa was partitioned into two equal halves, the effect of topical 16,16-dimethyl PGE2 (DMPGE2) (1 microgram/ml of perfusate) and 8% and 40% ethanol on tissue levels of nonprotein sulfhydryl compounds was assessed. Both DMPGE2 and 8% ethanol significantly increased (P less than 0.005) mucosal levels of nonprotein sulfhydryls when compared with corresponding mucosa bathed with saline alone. In contrast, mucosa bathed with 40% ethanol showed significantly decreased levels. If mucosa was bathed with DMPGE2 or 8% ethanol prior to exposing the stomach to 40% ethanol, this depletion in sulfhydryl compounds was not observed. Since other experimental observations have shown that exogenously administered prostaglandins and mild irritants (such as low-dose alcohol) can prevent gastric mucosal damage by necrotizing agents (such as high-dose alcohol), our findings are consistent with the hypothesis that nonprotein sulfhydryls may play a role in mediating gastric mucosal protection.

Role of Lipoxygenases and the Lipoxin A4/Annexin 1 Receptor in Ischemia-Reperfusion-Induced Gastric Mucosal Damage in Rats

Pharmacology ◽  
2009 ◽  
Vol 84 (5) ◽  
pp. 294-299 ◽  
Author(s):  
Brigitta M. Peskar ◽  
Karlheinz Ehrlich ◽  
Rufina Schuligoi ◽  
Bernhard A. Peskar
Keyword(s):  
Ischemia Reperfusion ◽  
Mucosal Damage ◽  
Gastric Mucosal Damage ◽  
Lipoxin A4 ◽  
Annexin 1

A new in vitro model for ethanol-induced gastric mucosal damage

1999 ◽  
Vol 41 (4) ◽  
pp. 167-172 ◽  
Author(s):  
Yassir M.Al-Mulla Hummadi ◽  
Rafid A Najim ◽  
Imad B Farjou
Keyword(s):  
In Vitro Model ◽  
Mucosal Damage ◽  
Gastric Mucosal Damage ◽  
Vitro Model
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