Application of Process Analytical Technology for Monitoring Freeze-Drying of an Amorphous Protein Formulation: Use of Complementary Tools for Real-Time Product Temperature Measurements and Endpoint Detection

2015 ◽  
Vol 104 (5) ◽  
pp. 1741-1749 ◽  
Author(s):  
Stefan C. Schneid ◽  
Robert E. Johnson ◽  
M. Laviniam Lewis ◽  
Peter Stärtzel ◽  
Henning Gieseler
Keyword(s):  
Real Time ◽  
Freeze Drying ◽  
Process Analytical Technology ◽  
Temperature Measurements ◽  
Protein Formulation ◽  
Endpoint Detection ◽  
Product Temperature ◽  
Analytical Technology

Potential of Near-Infrared Chemical Imaging as Process Analytical Technology Tool for Continuous Freeze-Drying

2018 ◽  
Vol 90 (7) ◽  
pp. 4354-4362 ◽  
Author(s):  
Davinia Brouckaert ◽  
Laurens De Meyer ◽  
Brecht Vanbillemont ◽  
Pieter-Jan Van Bockstal ◽  
Joris Lammens ◽  
...  
Keyword(s):  
Freeze Drying ◽  
Near Infrared ◽  
Process Analytical Technology ◽  
Chemical Imaging ◽  
Technology Tool ◽  
Analytical Technology

scholarly journals Multi-angle light scattering as a process analytical technology measuring real-time molecular weight for downstream process control

mAbs ◽  
2018 ◽  
pp. 1-6
Author(s):  
Bhumit A. Patel ◽  
Adrian Gospodarek ◽  
Michael Larkin ◽  
Sophia A. Kenrick ◽  
Mark A. Haverick ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Light Scattering ◽  
Process Control ◽  
Real Time ◽  
Process Analytical Technology ◽  
Downstream Process ◽  
Analytical Technology

In situ real time monitoring of emulsification and homogenization processes for vaccine adjuvants

The Analyst ◽  
2022 ◽  
Author(s):  
Nicole M. Ralbovsky ◽  
Randal J. Soukup ◽  
Justin P. Lomont ◽  
Mackenzie L. Lauro ◽  
Amanda Gulasarian ◽  
...  
Keyword(s):  
Real Time ◽  
Process Analytical Technology ◽  
Vaccine Adjuvant ◽  
Formation Processes ◽  
Vaccine Adjuvants ◽  
Stable Emulsion ◽  
Real Time Monitoring ◽  
Analytical Technology

Process analytical technology was used to monitor formation of a stable emulsion product, with results providing improved understanding of emulsion-based vaccine adjuvant formation processes.

Sign in / Sign up

Export Citation Format

Share Document