Liposomal Delivery System Enhances Anti-Inflammatory Properties of Curcumin

2012 ◽  
Vol 101 (2) ◽  
pp. 598-609 ◽  
Author(s):  
Purusotam Basnet ◽  
Haider Hussain ◽  
Ingunn Tho ◽  
Natasa Skalko-Basnet
2018 ◽  
Vol Volume 13 ◽  
pp. 763-776 ◽  
Author(s):  
Xiao-qian Dou ◽  
Hua Wang ◽  
Jing Zhang ◽  
Fang Wang ◽  
Gui-li Xu ◽  
...  

2021 ◽  
Vol 27 ◽  
Author(s):  
Bapi Gorain ◽  
Bandar E. Al-Dhubiab ◽  
Anroop Nair ◽  
Prashant Kesharwani ◽  
Manisha Pandey ◽  
...  

: The advancement of delivery tools for therapeutic agents has brought several novel formulations with increased drug loading, sustained release, targeted delivery, and prolonged efficacy. Amongst the several novel delivery approaches, multivesicular liposome has gained potential interest because this delivery system possesses the above advantages. In addition, this multivesicular liposomal delivery prevents degradation of the entrapped drug within the physiological environment while administered. The special structure of the vesicles allowed successful entrapment of hydrophobic and hydrophilic therapeutic agents, including proteins and peptides. Furthermore, this novel formulation could maintain the desired drug concentration in the plasma for a prolonged period, which helps to reduce the dosing frequencies, improve bioavailability, and safety. This tool could also provide stability of the formulation, and finally gaining patient compliance. Several multivesicular liposomes received approval for clinical research, while others are at different stages of laboratory research. In this review, we have focused on the preparation of multivesicular liposomes along with their application in different ailments for the improvement of the performance of the entrapped drug. Moreover, the challenges of delivering multivesicular vesicles have also been emphasized. Overall, it could be inferred that multivesicular liposomal delivery is a novel platform of advanced drug delivery with improved efficacy and safety.


1997 ◽  
Vol 83 (1) ◽  
pp. 87-90 ◽  
Author(s):  
Meng-Feng Shieh ◽  
I-Ming Chu ◽  
Chau-Jen Lee ◽  
Pei Kan ◽  
Dou-Mong Hau ◽  
...  

2017 ◽  
Vol 5 (4) ◽  
pp. 817-825 ◽  
Author(s):  
Eva Beňová ◽  
Vladimír Zeleňák ◽  
Dáša Halamová ◽  
Miroslav Almáši ◽  
Veronika Petrul'ová ◽  
...  

Mesoporous silica modified by p-coumaric acid derivatives as photo-switchable ligands was studied for the delivery of a non-steroidal anti-inflammatory drug.


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