Drug interactions between HIV protease inhibitors based on physiologically-based pharmacokinetic model

Nobuhito Shibata; Weihua Gao; Hiroyuki Okamoto; Tomoyuki Kishida; Koji Iwasaki; Yukako Yoshikawa; Kanji Takada

doi:10.1002/jps.10051

Drug interactions between HIV protease inhibitors based on physiologically-based pharmacokinetic model

Journal of Pharmaceutical Sciences ◽

10.1002/jps.10051 ◽

2002 ◽

Vol 91 (3) ◽

pp. 680-689 ◽

Cited By ~ 19

Author(s):

Nobuhito Shibata ◽

Weihua Gao ◽

Hiroyuki Okamoto ◽

Tomoyuki Kishida ◽

Koji Iwasaki ◽

...

Keyword(s):

Drug Interactions ◽

Protease Inhibitors ◽

Pharmacokinetic Model ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug–Drug Interactions

Clinical Pharmacokinetics ◽

10.1007/s40262-019-00856-z ◽

2019 ◽

Vol 59 (6) ◽

pp. 781-808 ◽

Cited By ~ 5

Author(s):

Xia Li ◽

Sebastian Frechen ◽

Daniel Moj ◽

Thorsten Lehr ◽

Max Taubert ◽

...

Keyword(s):

Drug Interactions ◽

Genetic Polymorphisms ◽

Pharmacokinetic Model ◽

Time Dependent ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Dependent Inhibition ◽

Time Dependent Inhibition

Download Full-text

Physiologically Based Pharmacokinetic Model Predictions of Panobinostat (LBH589) as a Victim and Perpetrator of Drug-Drug Interactions

Drug Metabolism and Disposition ◽

10.1124/dmd.117.076851 ◽

2017 ◽

Vol 45 (12) ◽

pp. 1304-1316 ◽

Cited By ~ 13

Author(s):

Heidi J. Einolf ◽

Wen Lin ◽

Christina S. Won ◽

Lai Wang ◽

Helen Gu ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based

Download Full-text

Development of Guanfacine Extended-Release Dosing Strategies in Children and Adolescents with ADHD Using a Physiologically Based Pharmacokinetic Model to Predict Drug–Drug Interactions with Moderate CYP3A4 Inhibitors or Inducers

Pediatric Drugs ◽

10.1007/s40272-017-0270-0 ◽

2017 ◽

Vol 20 (2) ◽

pp. 181-194 ◽

Cited By ~ 7

Author(s):

Aiqun Li ◽

Karen Yeo ◽

Devin Welty ◽

Haojing Rong

Keyword(s):

Drug Interactions ◽

Children And Adolescents ◽

Extended Release ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Dosing Strategies ◽

Cyp3a4 Inhibitors

Download Full-text

Physiologically‐Based Pharmacokinetic Model‐Informed Drug Development for Fenebrutinib: Understanding Complex Drug‐Drug Interactions

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12515 ◽

2020 ◽

Vol 9 (6) ◽

pp. 332-341

Author(s):

Yuan Chen ◽

Fang Ma ◽

Nicholas S. Jones ◽

Kenta Yoshida ◽

Po‐Chang Chiang ◽

...

Keyword(s):

Drug Development ◽

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Complex Drug

Download Full-text

Prediction of Drug-Drug Interactions with Bupropion and Its Metabolites as CYP2D6 Inhibitors Using a Physiologically-Based Pharmacokinetic Model

Pharmaceutics ◽

10.3390/pharmaceutics10010001 ◽

2017 ◽

Vol 10 (1) ◽

pp. 1 ◽

Cited By ~ 8

Author(s):

Caifu Xue ◽

Xunjie Zhang ◽

Weimin Cai

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Cyp2d6 Inhibitors

Download Full-text

Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model

Drug Metabolism and Disposition ◽

10.1124/dmd.115.064618 ◽

2015 ◽

Vol 43 (10) ◽

pp. 1417-1429 ◽

Cited By ~ 27

Author(s):

Shinji Yamazaki ◽

Theodore R. Johnson ◽

Bill J. Smith

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Correction to: Development of Guanfacine Extended-Release Dosing Strategies in Children and Adolescents with ADHD Using a Physiologically Based Pharmacokinetic Model to Predict Drug–Drug Interactions with Moderate CYP3A4 Inhibitors or Inducers

Pediatric Drugs ◽

10.1007/s40272-017-0275-8 ◽

2017 ◽

Vol 20 (2) ◽

pp. 205-205

Author(s):

Aiqun Li ◽

Karen Yeo ◽

Devin Welty ◽

Haojing Rong

Keyword(s):

Drug Interactions ◽

Children And Adolescents ◽

Extended Release ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Dosing Strategies ◽

Cyp3a4 Inhibitors

Download Full-text

Use of a physiologically based pharmacokinetic model to simulate drug–drug interactions between antineoplastic and antiretroviral drugs

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dkw485 ◽

2016 ◽

pp. dkw485

Author(s):

José Moltó ◽

Rajith Rajoli ◽

David Back ◽

Marta Valle ◽

Cristina Miranda ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Antiretroviral Drugs ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Reduced physiologically-based pharmacokinetic model of dabigatran etexilate-dabigatran and its application for prediction of intestinal P-gp-mediated drug-drug interactions

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2021.105932 ◽

2021 ◽

pp. 105932

Author(s):

Jennifer Lang ◽

Ludwig Vincent ◽

Marylore Chenel ◽

Kayode Ogungbenro ◽

Aleksandra Galetin

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Dabigatran Etexilate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

A Physiologically Based Pharmacokinetic Model to Predict Potential Drug–Drug Interactions and Inform Dosing of Acumapimod, an Oral p38 MAPK Inhibitor

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12565 ◽

2020 ◽

Author(s):

Alex Agyemang ◽

Colm Farrell ◽

William Moore ◽

Jacqueline Parkin

Keyword(s):

Drug Interactions ◽

P38 Mapk ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Potential Drug ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

P38 Mapk Inhibitor ◽

Mapk Inhibitor

Download Full-text