Use of a physiologically based pharmacokinetic model to simulate drug–drug interactions between antineoplastic and antiretroviral drugs

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dkw485 ◽

2016 ◽

pp. dkw485

Author(s):

José Moltó ◽

Rajith Rajoli ◽

David Back ◽

Marta Valle ◽

Cristina Miranda ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Antiretroviral Drugs ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug–Drug Interactions

Clinical Pharmacokinetics ◽

10.1007/s40262-019-00856-z ◽

2019 ◽

Vol 59 (6) ◽

pp. 781-808 ◽

Cited By ~ 5

Author(s):

Xia Li ◽

Sebastian Frechen ◽

Daniel Moj ◽

Thorsten Lehr ◽

Max Taubert ◽

...

Keyword(s):

Drug Interactions ◽

Genetic Polymorphisms ◽

Pharmacokinetic Model ◽

Time Dependent ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Dependent Inhibition ◽

Time Dependent Inhibition

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Physiologically Based Pharmacokinetic Model Predictions of Panobinostat (LBH589) as a Victim and Perpetrator of Drug-Drug Interactions

Drug Metabolism and Disposition ◽

10.1124/dmd.117.076851 ◽

2017 ◽

Vol 45 (12) ◽

pp. 1304-1316 ◽

Cited By ~ 13

Author(s):

Heidi J. Einolf ◽

Wen Lin ◽

Christina S. Won ◽

Lai Wang ◽

Helen Gu ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based

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Development of Guanfacine Extended-Release Dosing Strategies in Children and Adolescents with ADHD Using a Physiologically Based Pharmacokinetic Model to Predict Drug–Drug Interactions with Moderate CYP3A4 Inhibitors or Inducers

Pediatric Drugs ◽

10.1007/s40272-017-0270-0 ◽

2017 ◽

Vol 20 (2) ◽

pp. 181-194 ◽

Cited By ~ 7

Author(s):

Aiqun Li ◽

Karen Yeo ◽

Devin Welty ◽

Haojing Rong

Keyword(s):

Drug Interactions ◽

Children And Adolescents ◽

Extended Release ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Dosing Strategies ◽

Cyp3a4 Inhibitors

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Physiologically‐Based Pharmacokinetic Model‐Informed Drug Development for Fenebrutinib: Understanding Complex Drug‐Drug Interactions

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12515 ◽

2020 ◽

Vol 9 (6) ◽

pp. 332-341

Author(s):

Yuan Chen ◽

Fang Ma ◽

Nicholas S. Jones ◽

Kenta Yoshida ◽

Po‐Chang Chiang ◽

...

Keyword(s):

Drug Development ◽

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Complex Drug

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Prediction of Drug-Drug Interactions with Bupropion and Its Metabolites as CYP2D6 Inhibitors Using a Physiologically-Based Pharmacokinetic Model

Pharmaceutics ◽

10.3390/pharmaceutics10010001 ◽

2017 ◽

Vol 10 (1) ◽

pp. 1 ◽

Cited By ~ 8

Author(s):

Caifu Xue ◽

Xunjie Zhang ◽

Weimin Cai

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Cyp2d6 Inhibitors

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Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model

Drug Metabolism and Disposition ◽

10.1124/dmd.115.064618 ◽

2015 ◽

Vol 43 (10) ◽

pp. 1417-1429 ◽

Cited By ~ 27

Author(s):

Shinji Yamazaki ◽

Theodore R. Johnson ◽

Bill J. Smith

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Correction to: Development of Guanfacine Extended-Release Dosing Strategies in Children and Adolescents with ADHD Using a Physiologically Based Pharmacokinetic Model to Predict Drug–Drug Interactions with Moderate CYP3A4 Inhibitors or Inducers

Pediatric Drugs ◽

10.1007/s40272-017-0275-8 ◽

2017 ◽

Vol 20 (2) ◽

pp. 205-205

Author(s):

Aiqun Li ◽

Karen Yeo ◽

Devin Welty ◽

Haojing Rong

Keyword(s):

Drug Interactions ◽

Children And Adolescents ◽

Extended Release ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Dosing Strategies ◽

Cyp3a4 Inhibitors

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Reduced physiologically-based pharmacokinetic model of dabigatran etexilate-dabigatran and its application for prediction of intestinal P-gp-mediated drug-drug interactions

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2021.105932 ◽

2021 ◽

pp. 105932

Author(s):

Jennifer Lang ◽

Ludwig Vincent ◽

Marylore Chenel ◽

Kayode Ogungbenro ◽

Aleksandra Galetin

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Dabigatran Etexilate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Physiologically Based Pharmacokinetic Model to Predict Potential Drug–Drug Interactions and Inform Dosing of Acumapimod, an Oral p38 MAPK Inhibitor

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12565 ◽

2020 ◽

Author(s):

Alex Agyemang ◽

Colm Farrell ◽

William Moore ◽

Jacqueline Parkin

Keyword(s):

Drug Interactions ◽

P38 Mapk ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Potential Drug ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

P38 Mapk Inhibitor ◽

Mapk Inhibitor

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Physiologically based pharmacokinetic model predictions of ivosidenib (AG-120) as a victim and perpetrator of drug–drug interactions

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2018.09.238 ◽

2019 ◽

Vol 34 (1) ◽

pp. S70

Author(s):

Chandra Prakash ◽

Yue Chen ◽

Bin Fan ◽

David Dai ◽

Kha Le ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based

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