The relationship between knee loading during gait and cartilage thickness in nontraumatic and posttraumatic knee osteoarthritis

2021 ◽  
Author(s):  
Anthony Teoli ◽  
Melissa Cloutier‐Gendron ◽  
Shirley Y. K. Ho ◽  
Susan Gu ◽  
Jean‐Pierre Pelletier ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Cartilage Thickness ◽  
Knee Loading ◽  
The Relationship ◽  
And Cartilage

Effects of platelet-rich plasma on the clinical outcomes and cartilage thickness in patients with knee osteoarthritis

2019 ◽  
pp. 1-9 ◽  
Author(s):  
Ekin İlke Şen ◽  
Mustafa Aziz Yıldırım ◽  
Tuğba Yeşilyurt ◽  
Fatma Nur Kesiktaş ◽  
Demirhan Dıraçoğlu
Keyword(s):  
Knee Osteoarthritis ◽  
Clinical Outcomes ◽  
Platelet Rich Plasma ◽  
Cartilage Thickness ◽  
And Cartilage

scholarly journals Relationship between medial meniscus extrusion and cartilage measurements in the knee by fully automatic three-dimensional MRI analysis

2020 ◽  
Author(s):  
Hayato Aoki ◽  
Nobutake Ozeki ◽  
Hisako Katano ◽  
Akinobu Hyodo ◽  
Yugo Miura ◽  
...  
Keyword(s):  
Medial Meniscus ◽  
Three Dimensional ◽  
Study Data ◽  
Cartilage Thickness ◽  
Similarity Coefficients ◽  
Tibial Cartilage ◽  
The Relationship ◽  
Medial Meniscus Extrusion ◽  
Meniscus Extrusion ◽  
And Cartilage

Abstract Background: We developed a fully automatic three-dimensional knee MRI analysis software that can quantify meniscus extrusion and cartilage measurements, including the projected cartilage area ratio (PCAR), which represents the ratio of the subject’s actual cartilage area to their ideal cartilage area. We also collected 3D MRI knee data from 561 volunteers (aged 30–79 years) from the “Kanagawa Knee Study.” Our purposes were to verify the accuracy of the software for automatic cartilage and meniscus segmentation using knee MRI and to examine the relationship between medial meniscus extrusion measurements and cartilage measurements from Kanagawa Knee Study data. Methods: We constructed a neural network for the software by randomly choosing 10 healthy volunteers and 103 patients with knee pain. We validated the algorithm by randomly selecting 108 of these 113 subjects for training, and determined Dice similarity coefficients from five other subjects. We constructed a neural network using all data (113 subjects) for training. Cartilage thickness, cartilage volume, and PCAR in the medial femoral, lateral femoral, medial tibial, and lateral tibial regions were quantified by using the trained software on Kanagawa Knee Study data and their relationship with subject height was investigated. We also quantified the medial meniscus coverage ratio (MMCR), defined as the ratio of the overlapping area between the medial meniscus area and the medial tibial cartilage area to the medial tibial cartilage area. Finally, we examined the relationship between MMCR and PCAR at middle central medial tibial (mcMT) subregion located in the center of nine subregions in the medial tibial cartilage. Results: Dice similarity coefficients for cartilage and meniscus were both approximately 0.9. The femoral and tibial cartilage thickness and volume at each region correlated with height, but PCAR did not correlate with height in most settings. PCAR at the mcMT was significantly correlated with MMCR. Conclusions: Our software showed high segmentation accuracy for the knee cartilage and meniscus. PCAR was more useful than cartilage thickness or volume since it was less affected by height. A relationship was observed between the medial tibial cartilage measurements and the medial meniscus extrusion measurement in our cross-sectional study.

scholarly journals Relationship between medial meniscus extrusion and cartilage measurements in the knee by fully automatic three-dimensional MRI analysis

2020 ◽  
Author(s):  
Hayato Aoki ◽  
Nobutake Ozeki ◽  
Hisako Katano ◽  
Akinobu Hyodo ◽  
Yugo Miura ◽  
...  
Keyword(s):  
Medial Meniscus ◽  
Three Dimensional ◽  
Cartilage Thickness ◽  
Similarity Coefficients ◽  
Tibial Cartilage ◽  
Fully Automatic ◽  
The Relationship ◽  
Medial Meniscus Extrusion ◽  
Meniscus Extrusion ◽  
And Cartilage

Abstract BackgroundWe developed a fully automatic three-dimensional knee MRI analysis software that can quantify meniscus extrusion and cartilage measurements, including the projected cartilage area ratio (PCAR), which represents the ratio of the subject’s actual cartilage area to their ideal cartilage area. We also collected 3D MRI knee data from 561 volunteers (aged 30–79 years) from the “Kanagawa Knee Study.” Our purposes were to verify the accuracy of the software for automatic cartilage and meniscus segmentation using knee MRI and to examine the relationship between medial meniscus extrusion measurements and cartilage measurements from Kanagawa Knee Study data.MethodsWe constructed a neural network for the software by randomly choosing 10 healthy volunteers and 103 patients with knee pain. We validated the algorithm by randomly selecting 108 of these 113 subjects for training, and determined Dice similarity coefficients from five other subjects. We constructed a neural network using all data (113 subjects) for training. Cartilage thickness, cartilage volume, and PCAR in the medial femoral, lateral femoral, medial tibial, and lateral tibial regions were quantified by using the trained software on Kanagawa Knee Study data and their relationship with subject height was investigated. We also quantified the medial meniscus coverage ratio (MMCR), defined as the ratio of the overlapping area between the medial meniscus area and the medial tibial cartilage area to the medial tibial cartilage area. Finally, we examined the relationship between MMCR and PCAR at middle central medial tibial (mcMT) subregion located in the center of nine subregions in the medial tibial cartilage.ResultsDice similarity coefficients for cartilage and meniscus were both approximately 0.9. The femoral and tibial cartilage thickness and volume at each region correlated with height, but PCAR did not correlate with height in most settings. PCAR at the mcMT was significantly correlated with MMCR.ConclusionsOur software showed high segmentation accuracy for the knee cartilage and meniscus. PCAR was more useful than cartilage thickness or volume since it was less affected by height. A relationship was observed between the medial tibial cartilage measurements and the medial meniscus extrusion measurement in our cross-sectional study.Trial registration: UMIN, UMIN000032826; 1 September 2018,https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000037299

scholarly journals The relationship between reductions in knee loading and immediate pain response whilst wearing lateral wedged insoles in knee osteoarthritis

2014 ◽  
Vol 32 (9) ◽  
pp. 1147-1154 ◽  
Author(s):  
Richard K. Jones ◽  
Graham J. Chapman ◽  
Laura Forsythe ◽  
Matthew J. Parkes ◽  
David T. Felson
Keyword(s):  
Knee Osteoarthritis ◽  
Pain Response ◽  
Knee Loading ◽  
The Relationship

scholarly journals 138 WITHIN-REGION ANALYSIS OF THE RELATIONSHIP BETWEEN BONE AND CARTILAGE LESIONS IN KNEE OSTEOARTHRITIS

2008 ◽  
Vol 16 ◽  
pp. S73
Author(s):  
A. Kurani ◽  
S. Cahue ◽  
A. Guermazi ◽  
J. Song ◽  
D. Dunlop ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Cartilage Lesions ◽  
Region Analysis ◽  
The Relationship ◽  
And Cartilage
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