scholarly journals The relationship between reductions in knee loading and immediate pain response whilst wearing lateral wedged insoles in knee osteoarthritis

2014 ◽  
Vol 32 (9) ◽  
pp. 1147-1154 ◽  
Author(s):  
Richard K. Jones ◽  
Graham J. Chapman ◽  
Laura Forsythe ◽  
Matthew J. Parkes ◽  
David T. Felson
Author(s):  
Anthony Teoli ◽  
Melissa Cloutier‐Gendron ◽  
Shirley Y. K. Ho ◽  
Susan Gu ◽  
Jean‐Pierre Pelletier ◽  
...  

2009 ◽  
Vol 69 (6) ◽  
pp. 1151-1154 ◽  
Author(s):  
Kim L Bennell ◽  
Mark W Creaby ◽  
Tim V Wrigley ◽  
Kelly-Ann Bowles ◽  
Rana S Hinman ◽  
...  

ObjectivesTo evaluate the relationship between mechanical loading, as indicated by the external knee adduction moment (KAM) during walking, and BML on MRI in people with medial knee osteoarthritis.MethodsMeasures were taken in 91 individuals with medial knee osteoarthritis. Logistic regression analyses were performed with the presence/absence of medial tibial or medial femoral BML as the outcome and either peak KAM or KAM impulse as the independent variable. Analyses were also adjusted for age, gender, body mass index, alignment and walking speed.ResultsIn adjusted analyses, peak KAM was significantly related to medial tibial (OR 2.3; 95%CI 1.07 to 4.7), but not medial femoral (OR 1.85; 95%CI 0.93 to 3.7) BML. KAM impulse was significantly related to both medial tibial (OR 9.4; 95%CI 1.53 to 57.2) and medial femoral (OR 14.4; 95%CI 2.3 to 89.8) BML.ConclusionsThe findings support the hypothesis that greater mechanical loading of the medial compartment plays a role in the pathogenesis of BML in medial tibiofemoral osteoarthritis.


2013 ◽  
Vol 65 (5) ◽  
pp. 1282-1289 ◽  
Author(s):  
Najia Shakoor ◽  
Roy H. Lidtke ◽  
Markus A. Wimmer ◽  
Rachel A. Mikolaitis ◽  
Kharma C. Foucher ◽  
...  

2021 ◽  
Vol 51 (10) ◽  
pp. 492-502
Author(s):  
Jay-Shian Tan ◽  
Edward Tikoft ◽  
Peter O'Sullivan ◽  
Anne Smith ◽  
Amity Campbell ◽  
...  

2011 ◽  
Vol 70 (10) ◽  
pp. 1770-1774 ◽  
Author(s):  
Kim L Bennell ◽  
Kelly-Ann Bowles ◽  
Yuanyuan Wang ◽  
Flavia Cicuttini ◽  
Miranda Davies-Tuck ◽  
...  

ObjectiveMechanical factors, in particular increased medial knee joint load, are believed to be important in the structural progression of knee osteoarthritis. This study evaluated the relationship of medial knee load during walking to indices of structural disease progression, measured on MRI, in people with medial knee osteoarthritis.MethodsA longitudinal cohort design utilising a subset of participants (n=144, 72%) enrolled in a randomised controlled trial of lateral wedge insoles was employed. Medial knee load parameters including the peak knee adduction moment (KAM) and the KAM impulse were measured at baseline using three-dimensional gait analysis during walking. MRI at baseline and at 12 months was used to assess structural indices. Multiple regression with adjustment for covariates assessed the relationship between medial knee load parameters and the annual change in medial tibial cartilage volume. Binary logistic regression was used for the dichotomous variables of progression of medial tibiofemoral cartilage defects and bone marrow lesions (BML).ResultsA higher KAM impulse, but not peak KAM, at baseline was independently associated with greater loss of medial tibial cartilage volume over 12 months (β=29.9, 95% CI 6.3 to 53.5, p=0.01). No significant relationships were seen between medial knee load parameters and the progression of medial tibiofemoral cartilage defects or BML.ConclusionThis study suggests knee loading, in particular the KAM impulse, may be a risk factor for loss of medial tibial cartilage volume. As knee load is modifiable, load-modifying treatments may potentially slow disease progression.


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