Effects of intermittent hydrostatic pressure and BMP-2 on osteoarthritic human chondrocyte metabolism in vitro

2010 ◽  
Vol 29 (3) ◽  
pp. 361-368 ◽  
Author(s):  
R.L. Smith ◽  
D.P. Lindsey ◽  
L. Dhulipala ◽  
A.H.S. Harris ◽  
S.B. Goodman ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
Human Chondrocyte ◽  
Chondrocyte Metabolism

scholarly journals Effects of tensile strain and fluid flow on osteoarthritic human chondrocyte metabolism in vitro

2010 ◽  
Vol 28 (7) ◽  
pp. 907-913 ◽  
Author(s):  
Taro Mawatari ◽  
Derek P. Lindsey ◽  
Alex H.S. Harris ◽  
Stuart B. Goodman ◽  
William J. Maloney ◽  
...  
Keyword(s):  
Fluid Flow ◽  
Tensile Strain ◽  
Human Chondrocyte ◽  
Chondrocyte Metabolism

Effects of hydrostatic pressure and inert gases on platelet aggregation in vitro

1990 ◽  
Vol 69 (6) ◽  
pp. 2239-2247 ◽  
Author(s):  
D. M. Pickles ◽  
D. Ogston ◽  
A. G. Macdonald
Keyword(s):  
Platelet Aggregation ◽  
Hydrostatic Pressure ◽  
Maximum Degree ◽  
Platelet Rich Plasma ◽  
Control Level ◽  
Inert Gases ◽  
Partial Pressures ◽  
Compression Cycle ◽  
Anesthetic Potency

A novel cuvette was used to subject citrated platelet-rich plasma (PRP) to high hydrostatic pressure with negligible contamination by He (used for compression of the apparatus). Aggregation was induced at pressure by ADP and quantified turbidimetrically. The maximum degree of aggregation (MDA) was reduced from a control level of 82.2 to 53.6% by exposure to 101 ATA. Because decompression bubbles did not form, aggregation was also measured immediately after a compression cycle. After exposure to 101 ATA hydrostatic pressure, platelets responded normally to ADP at 1 ATA. In a matching apparatus, PRP was equilibrated with high partial pressures of inert gases. Normal physiological plasma Po2 and pH were maintained during equilibration. N2O (5 ATA) reduced the MDA from 86.5 (control) to 58.1%. N2 (51 ATA) reduced the MDA from 74.7 (control) to 51.6%, and 101 ATA Pn2 reduced the MDA from 78.0 (control) to 32.3%. He (100 ATA) reduced the MDA from 83.6 to 38.6%. It was concluded that platelet aggregation was relatively sensitive to hydrostatic pressure and less sensitive to inert gases than predicted from their anesthetic potency ratios.

Cyclic hydrostatic pressure stimulates enhanced bone development in the foetal chick femur in vitro

Bone ◽  
2013 ◽  
Vol 53 (2) ◽  
pp. 468-477 ◽  
Author(s):  
J.R. Henstock ◽  
M. Rotherham ◽  
J.B. Rose ◽  
A.J. El Haj
Keyword(s):  
Hydrostatic Pressure ◽  
Bone Development

scholarly journals High hydrostatic pressure: a new way to improve in vitro developmental competence of porcine matured oocytes after vitrification

Reproduction ◽  
2007 ◽  
Vol 135 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Y Du ◽  
C S Pribenszky ◽  
M Molnar ◽  
X Zhang ◽  
H Yang ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
High Hydrostatic Pressure ◽  
Developmental Competence

ChemInform Abstract: Synthesis and in vitro Evaluation of 5-Arylidene-3-hydroxyalkyl-2-phenylimino-4-thiazolidinones (V) with Antidegenerative Activity on Human Chondrocyte Cultures.

ChemInform ◽  
2008 ◽  
Vol 39 (11) ◽  
Author(s):  
Rosaria Ottana ◽  
Rosanna Maccari ◽  
Rosella Ciurleo ◽  
Maria Gabriella Vigorita ◽  
Anna Maria Panico ◽  
...  
Keyword(s):  
In Vitro Evaluation ◽  
Human Chondrocyte ◽  
Chondrocyte Cultures

Nanog maintains human chondrocyte phenotype and function in vitro

2009 ◽  
Vol 28 (4) ◽  
pp. 516-521 ◽  
Author(s):  
Hongjun Zheng ◽  
Francoise Gourronc ◽  
Joseph A. Buckwalter ◽  
James A. Martin
Keyword(s):  
Chondrocyte Phenotype ◽  
Human Chondrocyte ◽  
And Function

scholarly journals A Human Chondrocyte-Derived In Vitro Model of Alcohol-Induced and Steroid-Induced Femoral Head Necrosis

2018 ◽  
Vol 24 ◽  
pp. 539-547 ◽  
Author(s):  
Xiong Qin ◽  
Pan Jin ◽  
Tongmeng Jiang ◽  
Muyan Li ◽  
Jiachang Tan ◽  
...  
Keyword(s):  
Femoral Head ◽  
In Vitro Model ◽  
Femoral Head Necrosis ◽  
Human Chondrocyte ◽  
Vitro Model
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