scholarly journals Hyaluronic acid and chondroitin sulfate content of osteoarthritic human knee cartilage: Site-specific correlation with weight-bearing force based on femorotibial angle measurement

2008 ◽  
Vol 26 (9) ◽  
pp. 1194-1198 ◽  
Author(s):  
Shuhei Otsuki ◽  
Mikio Nakajima ◽  
Martin Lotz ◽  
Mitsuo Kinoshita
1997 ◽  
Vol 77 (4) ◽  
pp. 715-721 ◽  
Author(s):  
H. H. Sunwoo ◽  
L. Y. M. Sim ◽  
T. Nakano ◽  
R. J. Hudson ◽  
J. S. Sim

The emerging wapiti industry in North America is based largely on markets for velvet antlers which are used in oriental medicine. Despite the economic opportunity, enthusiasm has been dampened by incomplete understanding of the chemical and pharmacological properties of velvet antler. This study characterizes polysaccharide constituents of glycosaminoglycans in growing antler of wapiti (Cervus elaphus). Glycosaminoglycans were isolated from four sections (tip, upper, middle and base) of growing antlers, and were studied using cellulose acetate electrophoresis, gel electrophoresis, enzymatic digestion and gel chromatography. The tip and upper sections of the antler which are rich in cartilaginous tissues contained chondroitin sulfate as a major glycosaminoglycan with small amounts of hyaluronic acid. In the middle and base sections containing bone and bone marrow, chondroitin sulfate was also a major glycosaminoglycan with small amounts of hyaluronic acid and chondroitinase-ACI resistant materials. More than half of chondroitin sulfate from the middle and base sections had larger molecular size than did the chondroitin sulfates from the tip and upper sections. Key words: Glycosaminoglycans, chondroitin sulfate, antler, wapiti


2013 ◽  
Vol 26 (11) ◽  
pp. 1412-1419 ◽  
Author(s):  
Nikita Garnov ◽  
Wilfried Gründer ◽  
Gregor Thörmer ◽  
Robert Trampel ◽  
Robert Turner ◽  
...  
Keyword(s):  

2019 ◽  
Vol 16 (5) ◽  
pp. S75-S76
Author(s):  
C. Schiraldi ◽  
A. Stellavato ◽  
A. V. Adriana Pirozzi ◽  
P. Diana ◽  
G. Donnarumma ◽  
...  

ACS Omega ◽  
2021 ◽  
Author(s):  
Carl C. L. Schuurmans ◽  
Arwin J. Brouwer ◽  
Jacobus A. W. Jong ◽  
Geert-Jan P. H. Boons ◽  
Wim E. Hennink ◽  
...  

2015 ◽  
Vol 642 ◽  
pp. 94-98
Author(s):  
Chau Chang Chou ◽  
Yu Hsiang Hao ◽  
Fu Yin Hsu

The surface of high-pressure crystallized ultra-high molecular weight polyethylene (UHMWPE) was modified for application as an artificial cartilage material. A UHMWPE surface pretreated by a series of processes, including treatment with O2-plasma and ethylenediamine solution, was coated with hyaluronic acid (HA). After that, adipic acid dihydrazide (AAD) was added to partially crosslink the HA coating in order to enhance its durability. The modified samples were verified by water contact angle measurement and Fourier transform infrared spectrometry. Both HA layers, original and crosslinked, were also quantitatively evaluated by carbohydrate chemistry assay according to the absorbance of the incident light. The tribological performance of the samples was evaluated by a pin-on-disk test rig lubricated by normal saline under an average pressure of 18 MPa and at a sliding speed of 0.03 m/s for 45 h. The wear resistance of the HA-coated UHMWPE specimens promoted by the crosslink process was superior to that of the original HA-coated sample, and that resistance was maintained after immersion in saline solution for one month.


2018 ◽  
Vol 28 (8) ◽  
pp. 3384-3392 ◽  
Author(s):  
Alexander Kolb ◽  
Simon Robinson ◽  
David Stelzeneder ◽  
Markus Schreiner ◽  
Catharina Chiari ◽  
...  

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