Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord

2004 ◽  
Vol 76 (2) ◽  
pp. 232-243 ◽  
Author(s):  
Pavla Jendelová ◽  
Vít Herynek ◽  
Lucia Urdzíková ◽  
Kateřina Glogarová ◽  
Jana Kroupová ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Bone Marrow ◽  
Iron Oxide ◽  
Embryonic Stem Cells ◽  
Magnetic Resonance ◽  
Rat Brain ◽  
Embryonic Stem ◽  
Oxide Nanoparticles ◽  
Brain And Spinal Cord

Functional investigations on embryonic stem cells labeled with clinically translatable iron oxide nanoparticles

Nanoscale ◽  
2014 ◽  
Vol 6 (15) ◽  
pp. 9025 ◽  
Author(s):  
Jing Liu ◽  
Liqin Wang ◽  
Jianbo Cao ◽  
Yue Huang ◽  
Yu Lin ◽  
...  
Keyword(s):  
Stem Cells ◽  
Iron Oxide ◽  
Embryonic Stem Cells ◽  
Iron Oxide Nanoparticles ◽  
Embryonic Stem ◽  
Oxide Nanoparticles

Effects of iron oxide nanoparticles on cardiac differentiation of embryonic stem cells

2009 ◽  
Vol 379 (4) ◽  
pp. 898-903 ◽  
Author(s):  
Ka-Wing Au ◽  
Song-Yan Liao ◽  
Yee-Ki Lee ◽  
Wing-Hon Lai ◽  
Kwong-Man Ng ◽  
...  
Keyword(s):  
Stem Cells ◽  
Iron Oxide ◽  
Embryonic Stem Cells ◽  
Iron Oxide Nanoparticles ◽  
Embryonic Stem ◽  
Cardiac Differentiation ◽  
Oxide Nanoparticles

scholarly journals Spinal cord injury regeneration using autologous bone marrow-derived neurocytes and rat embryonic stem cells: A comparative study in rats

2020 ◽  
Vol 12 (12) ◽  
pp. 1591-1602
Author(s):  
Mir Sadat-Ali ◽  
Dakheel A Al-Dakheel ◽  
Ayesha Ahmed ◽  
Haifa A Al-Turki ◽  
Abdallah S Al-Omran ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Bone Marrow ◽  
Spinal Cord Injury ◽  
Embryonic Stem Cells ◽  
Comparative Study ◽  
Embryonic Stem ◽  
Autologous Bone Marrow ◽  
Cord Injury ◽  
Autologous Bone

In vivo detection limits of magnetically labeled embryonic stem cells in the rat brain using high-field (17.6 T) magnetic resonance imaging

NeuroImage ◽  
2005 ◽  
Vol 24 (3) ◽  
pp. 635-645 ◽  
Author(s):  
Albrecht Stroh ◽  
Cornelius Faber ◽  
Thomas Neuberger ◽  
Peer Lorenz ◽  
Katharina Sieland ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Magnetic Resonance ◽  
Rat Brain ◽  
High Field ◽  
Embryonic Stem ◽  
Resonance Imaging ◽  
In Vivo Detection

scholarly journals Magnetic resonance imaging tractography as a diagnostic tool in patients with spinal cord injury treated with human embryonic stem cells

2017 ◽  
Vol 30 (1) ◽  
pp. 71-79 ◽  
Author(s):  
Geeta Shroff
Keyword(s):  
Magnetic Resonance Imaging ◽  
Spinal Cord ◽  
Stem Cells ◽  
Spinal Cord Injury ◽  
Embryonic Stem Cells ◽  
Magnetic Resonance ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Resonance Imaging ◽  
Cord Injury

Introduction Spinal cord injury is a cause of severe disability and mortality. The pharmacological and non-pharmacological methods used, are unable to improve the quality of life in spinal cord injury. Spinal disorders have been treated with human embryonic stem cells. Magnetic resonance imaging and tractography were used as imaging modality to document the changes in the damaged cord, but the magnetic resonance imaging tractography was seen to be more sensitive in detecting the changes in the spinal cord. The present study was conducted to evaluate the diagnostic modality of magnetic resonance imaging tractography to determine the efficacy of human embryonic stem cells in chronic spinal cord injury. Materials and methods The study included the patients with spinal cord injury for whom magnetic resonance imaging tractography was performed before and after the therapy. Omniscan (gadodiamide) magnetic resonance imaging tractography was analyzed to assess the spinal defects and the improvement by human embryonic stem cell treatment. The patients were also scored by American Spinal Injury Association scale. Results Overall, 15 patients aged 15–44 years with clinical manifestations of spinal cord injury had magnetic resonance imaging tractography performed. The average treatment period was nine months. The majority of subjects ( n = 13) had American Spinal Injury Association score A, and two patients were at score C at the beginning of therapy. At the end of therapy, 10 patients were at score A, two patients were at score B and three patients were at score C. Improvements in patients were clearly understood through magnetic resonance imaging tractography as well as in clinical signs and symptoms. Conclusion Magnetic resonance imaging tractography can be a crucial diagnostic modality to assess the improvement in spinal cord injury patients.

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