Analysis of the full-length genome of genotype 4 hepatitis E virus isolates from patients with fulminant or acute self-limited hepatitis E

2006 ◽  
Vol 78 (4) ◽  
pp. 476-484 ◽  
Author(s):  
Jun Inoue ◽  
Tsutomu Nishizawa ◽  
Masaharu Takahashi ◽  
Tatsuya Aikawa ◽  
Hitoshi Mizuo ◽  
...  
2005 ◽  
Vol 86 (12) ◽  
pp. 3321-3326 ◽  
Author(s):  
Tsutomu Nishizawa ◽  
Masaharu Takahashi ◽  
Kazunori Endo ◽  
Shinji Fujiwara ◽  
Nobuo Sakuma ◽  
...  

Two (2·3 %) of 87 wild-caught boars in Japan had detectable hepatitis E virus (HEV) RNA. The two boar HEV isolates (wbJTS1 and wbJYG1) obtained in the present study and a previously reported isolate (wbJSG1) whose partial sequence had been determined were sequenced over the entire genome. The wbJSG1, wbJTS1 and wbJYG1 isolates comprised 7225 or 7226 nt, excluding the poly(A) tail, and segregated into genotype 3. They differed by 8·5–11·2 % from each other and by 8·6–18·4 % from 17 reported genotype 3 HEV isolates, including one boar isolate, in the full-length sequence. When compared with 191 reported genotype 3 HEV isolates whose partial sequences were known, these three boar isolates were closer to Japanese isolates than to isolates of non-Japanese origin (89·2±2·6 vs 85·9±2·2 %; P<0·0001). A proportion of wild boars in Japan are infected with markedly heterogeneous HEV strains that are indigenous to Japan and may serve as reservoirs of HEV.


Intervirology ◽  
2007 ◽  
Vol 50 (3) ◽  
pp. 181-189 ◽  
Author(s):  
Masami Koike ◽  
Kazuaki Takahashi ◽  
Shunji Mishiro ◽  
Atsushi Matsui ◽  
Mie Inao ◽  
...  

2007 ◽  
Vol 79 (8) ◽  
pp. 1128-1137 ◽  
Author(s):  
Felipe R. Lorenzo ◽  
Bira Tsatsralt-Od ◽  
Sanjaa Ganbat ◽  
Masaharu Takahashi ◽  
Hiroaki Okamoto

2017 ◽  
Vol 240 ◽  
pp. 147-153 ◽  
Author(s):  
Putu Prathiwi Primadharsini ◽  
Masao Miyake ◽  
Satoshi Kunita ◽  
Tsutomu Nishizawa ◽  
Masaharu Takahashi ◽  
...  

Kanzo ◽  
2006 ◽  
Vol 47 (3) ◽  
pp. 161-162 ◽  
Author(s):  
M Nakamura ◽  
K Taira ◽  
A Ohno ◽  
M Taira ◽  
H Sakugawa ◽  
...  

2017 ◽  
Vol 5 (35) ◽  
Author(s):  
Jakub Kubacki ◽  
Cornel Fraefel ◽  
Marco Jermini ◽  
Petra Giannini ◽  
Gladys Martinetti ◽  
...  

ABSTRACT We present here the full-length genome sequences of two hepatitis E virus genotype 3 (HEV-3) isolates from a human stool sample from a patient with acute hepatitis and a raw sausage containing pig liver. Sequence analysis implies that Swiss HEV isolates may form a novel subgroup of HEV-3 viruses.


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