scholarly journals Magnetization transfer (MT) asymmetry around the water resonance in human cervical spinal cord

2009 ◽  
Vol 29 (3) ◽  
pp. 523-528 ◽  
Author(s):  
Man-Cheuk Ng ◽  
Jun Hua ◽  
Yong Hu ◽  
Keith D. Luk ◽  
Edmund Y. Lam
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
Water Resonance

Measurement of magnetization transfer ratio (MTR) from cervical spinal cord: Multicenter reproducibility and variability

2018 ◽  
Vol 49 (6) ◽  
pp. 1777-1785 ◽  
Author(s):  
Benoit Combès ◽  
Laureline Monteau ◽  
Elise Bannier ◽  
Virginie Callot ◽  
Pierre Labauge ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
Magnetization Transfer Ratio ◽  
Transfer Ratio

scholarly journals Evaluating single-point quantitative magnetization transfer in the cervical spinal cord: Application to multiple sclerosis

2017 ◽  
Vol 16 ◽  
pp. 58-65 ◽  
Author(s):  
Alex K. Smith ◽  
Samantha By ◽  
Bailey D. Lyttle ◽  
Richard D. Dortch ◽  
Bailey A. Box ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
Single Point

scholarly journals Magnetization transfer weighted imaging in the upper cervical spinal cord using cerebrospinal fluid as intersubject normalization reference (MTCSF imaging)

2005 ◽  
Vol 54 (1) ◽  
pp. 201-206 ◽  
Author(s):  
Seth A. Smith ◽  
Golay Xavier ◽  
Fatemi Ali ◽  
Jones Craig K. ◽  
Raymond Gerald V. ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cerebrospinal Fluid ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
Upper Cervical

scholarly journals Macromolecular changes in spinal cord white matter characterize whiplash outcome at 1-year post motor vehicle collision

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Mark A. Hoggarth ◽  
James M. Elliott ◽  
Zachary A. Smith ◽  
Monica Paliwal ◽  
Mary J. Kwasny ◽  
...  
Keyword(s):  
Spinal Cord ◽  
White Matter ◽  
Motor Vehicle ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
White Matter Integrity ◽  
Vehicle Collisions ◽  
Intervertebral Disks ◽  
Vehicle Collision ◽  
Left And Right

AbstractEach year, whiplash injuries from motor vehicle collisions (MVC) affect millions worldwide, with no strong evidence of pathology. While the majority recover soon after the injury, the same is not true for roughly 20% reporting higher levels of pain and distress, without diagnostic options. This study used magnetization transfer (MT) imaging to quantify white matter integrity in 78 subjects with varying levels of pain, 1 year after MVC. MT images of the cervical spinal cord were collected parallel to the intervertebral disks. MT ratios (MTR) were calculated in select white matter tracts along with MTR homogeneity (MTRh) at each level. Significant differences were observed between clinical outcome groups in the left and right spinothalamic tracts (p = 0.003 and 0.020) and MTRh (p = 0.009). MTRh was elevated in females with poor recovery versus females reporting recovery (p < 0.001) or milder symptoms (p < 0.001), and in males reporting recovery (p = 0.007) or no recovery (p < 0.001). There was a significant interaction between recovery status and sex (p = 0.015). MT imaging identified tract specific and regional changes in white matter integrity suggesting potential insults to the cord. Additionally, significant MTRh differences between sexes were observed, characterizing the heterogeneity of whiplash recovery and worse outcomes in females.

scholarly journals Reproducibility of tract-specific magnetization transfer and diffusion tensor imaging in the cervical spinal cord at 3 tesla

2009 ◽  
pp. n/a-n/a ◽  
Author(s):  
Seth A. Smith ◽  
Craig K. Jones ◽  
Aliya Gifford ◽  
Visar Belegu ◽  
BettyAnn Chodkowski ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
3 Tesla ◽  
Specific Magnetization ◽  
And Diffusion

scholarly journals Quantitative magnetization transfer characteristics of the human cervical spinal cord in vivo: Application to Adrenomyeloneuropathy

2008 ◽  
Vol 61 (1) ◽  
pp. 22-27 ◽  
Author(s):  
Seth A. Smith ◽  
Xavier Golay ◽  
Ali Fatemi ◽  
Asif Mahmood ◽  
Gerald V. Raymond ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
Transfer Characteristics

scholarly journals An optimized framework for quantitative magnetization transfer imaging of the cervical spinal cord in vivo

2017 ◽  
Vol 79 (5) ◽  
pp. 2576-2588 ◽  
Author(s):  
Marco Battiston ◽  
Francesco Grussu ◽  
Andrada Ianus ◽  
Torben Schneider ◽  
Ferran Prados ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Magnetization Transfer ◽  
Magnetization Transfer Imaging

Alterations in the number of motoneurons containing immunoreactive calcitonin gene-related peptide(CGRP)& choline acetyltransferase(ChAT) in the cervical spinal cord of the wobbler mouse during the development of the motoneuron disease

1995 ◽  
Vol 53 ◽  
pp. 970-971
Author(s):  
L. Vacca-Galloway ◽  
Y.Q. Zhang ◽  
P. Bose ◽  
S.H. Zhang
Keyword(s):  
Spinal Cord ◽  
Early Stage ◽  
Cervical Spinal Cord ◽  
Wild Type Mouse ◽  
Reflex Response ◽  
Mouse Strains ◽  
Behavioral Tests ◽  
Wobbler Mouse ◽  
Stage 4 ◽  
Stage 1

The Wobbler mouse (wr) has been studied as a model for inherited human motoneuron diseases (MNDs). Using behavioral tests for forelimb power, walking, climbing, and the “clasp-like reflex” response, the progress of the MND can be categorized into early (Stage 1, age 21 days) and late (Stage 4, age 3 months) stages. Age-and sex-matched normal phenotype littermates (NFR/wr) were used as controls (Stage 0), as well as mice from two related wild-type mouse strains: NFR/N and a C57BI/6N. Using behavioral tests, we also detected pre-symptomatic Wobblers at postnatal ages 7 and 14 days. The mice were anesthetized and perfusion-fixed for immunocytochemical (ICC) of CGRP and ChAT in the spinal cord (C3 to C5).Using computerized morphomety (Vidas, Zeiss), the numbers of IR-CGRP labelled motoneurons were significantly lower in 14 day old Wobbler specimens compared with the controls (Fig. 1). The same trend was observed at 21 days (Stage 1) and 3 months (Stage 4). The IR-CGRP-containing motoneurons in the Wobbler specimens declined progressively with age.

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