scholarly journals Region-specific impairment of the cervical spinal cord (SC) in amyotrophic lateral sclerosis: A preliminary study using SC templates and quantitative MRI (diffusion tensor imaging/inhomogeneous magnetization transfer)

2017 ◽  
Vol 30 (12) ◽  
pp. e3801 ◽  
Author(s):  
Henitsoa Rasoanandrianina ◽  
Aude-Marie Grapperon ◽  
Manuel Taso ◽  
Olivier M. Girard ◽  
Guillaume Duhamel ◽  
...  
NeuroImage ◽  
2010 ◽  
Vol 53 (2) ◽  
pp. 576-583 ◽  
Author(s):  
Govind Nair ◽  
John D. Carew ◽  
Sharon Usher ◽  
Debbie Lu ◽  
Xiaoping P. Hu ◽  
...  

2017 ◽  
Vol 75 (5) ◽  
pp. 272-276 ◽  
Author(s):  
Marcelo Chaves ◽  
Mariela Bettini ◽  
Maria Cecilia Fernandez ◽  
Maria Jose Garcia Basalo ◽  
Juan Ignacio Rojas ◽  
...  

ABSTRACT The objective of this preliminary study was to correlate diffusion tensor imaging (DTI) alterations with the cognitive profile of patients with amyotrophic lateral sclerosis (ALS). Methods This was a case-control study conducted from December 1, 2012 to December 1, 2014. Clinical and demographic data were recorded. A neuropsychological test battery adapted to ALS patients was used. An MRI with DTI was performed in all patients and fractional anisotropy (FA) was analyzed in the white matter using the tract based spatial statistics program. Results Twenty-four patients with ALS (15 females, mean age 66.9 + -2.3) and 13 healthy controls (four females, average age 66.9 + - 2) were included. The DTI showed white matter damage in ALS patients vs. healthy controls (p < 0.001). Discussion In our preliminary study the alterations of white matter in DTI were significantly associated with cognitive impairment in patients with ALS.


2009 ◽  
pp. n/a-n/a ◽  
Author(s):  
Seth A. Smith ◽  
Craig K. Jones ◽  
Aliya Gifford ◽  
Visar Belegu ◽  
BettyAnn Chodkowski ◽  
...  

SLEEP ◽  
2016 ◽  
Vol 39 (2) ◽  
pp. 423-428 ◽  
Author(s):  
Klaas Lindemann ◽  
Hans-Peter Müller ◽  
Albert C. Ludolph ◽  
Magdolna Hornyak ◽  
Jan Kassubek

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