scholarly journals Daily and event‐driven pre‐exposure prophylaxis for men who have sex with men in Belgium: results of a prospective cohort measuring adherence, sexual behaviour and STI incidence

2019 ◽  
Vol 22 (10) ◽  
Author(s):  
Bea Vuylsteke ◽  
Thijs Reyniers ◽  
Irith De Baetselier ◽  
Christiana Nöstlinger ◽  
Tania Crucitti ◽  
...  
Keyword(s):  
Sexual Behaviour ◽  
Prospective Cohort ◽  
Event Driven ◽  
Sex With Men ◽  
Exposure Prophylaxis

scholarly journals Pre-exposure prophylaxis' knowledge, attitudes, practices amongst italian men who have sex with men

2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
G Voglino ◽  
MR Gualano ◽  
S Rousset ◽  
F Bert ◽  
R Siliquini ◽  
...  
Keyword(s):  
Sexual Behaviour ◽  
Online Survey ◽  
Healthcare Personnel ◽  
Attitudes And Practices ◽  
Barriers To Access ◽  
Immunodeficiency Virus ◽  
High Infection ◽  
Sex With Men ◽  
Prep Awareness ◽  
Exposure Prophylaxis

Abstract Background Pre-exposure prophylaxis (PrEP) is suitable for human immunodeficiency virus (HIV)high-infection-risk people, foremost amongst males who have sex with other males (MSM). This study evaluated knowledge, attitudes and practices regarding PrEP in a sample of Italian MSM, in order to hypothesize strategies to implement PrEP awareness and use. Methods An online survey was given to an opportunistic sample of Italian MSM. The questionnaire investigated sexual behaviour, knowledge on HIV and PrEP awareness, attitudes and practices. Univariable and multivariable logistic regressions were conducted to identify possible associations with PrEP knowledge. Results A total of 196 MSM completed the survey. Overall data showed very good HIV and safe sexual behaviour knowledge (94.4% of correct answers). Nevertheless, our sample rarely used PrEP because of existing barriers: high therapy price (26.9%)and fear of side effects (23.8%). Only 10.3% of partecipants were informed on HIV and PReP by institutional channels, even less (7.5%) from specialized physicians and general practitioners. The most significant association with PrEP knowledge was having regular HIV-tests (adjusted odds ratio (AdjOR) = 3.16; confidence interval (CI) = 1.06-9.29); Conclusions PreP's Knowledge was well established, but PrEP use was not widespread. It is necessary to improve communication on PrEP and to lower existing barriers in order to grant access to PrEP access. Key messages Barriers to access PrEP have to be lowered. Healthcare personnel has to be involved in PrEP's benefits communication.

scholarly journals Prevalence of Gastrointestinal Pathogens Detected by Multiplex PCR in a Prospective Cohort of Men Who Have Sex with Men (MSM) Taking HIV Pre-Exposure Prophylaxis (PrEP)—New York City, 2019-2020

2021 ◽  
Author(s):  
Lawrence Purpura ◽  
Jason Zucker ◽  
Elijah LaSota ◽  
Mabel Lopez ◽  
Rebecca Spicehandler ◽  
...  
Keyword(s):  
New York ◽  
New York City ◽  
Multiplex Pcr ◽  
York City ◽  
Prospective Cohort ◽  
Longitudinal Cohort ◽  
Gastrointestinal Pathogens ◽  
Sex With Men ◽  
Exposure Prophylaxis

Abstract Multiplex PCR testing for gastrointestinal pathogens was performed on a longitudinal cohort of 110 MSM taking HIV PrEP. At least one pathogen was detected among 50 (45%) participants, with some participants testing positive for the same pathogen on multiple consecutive visits over a period of months.

scholarly journals Understanding pre-exposure prophylaxis (PrEP) regimen use: Switching and discontinuing daily and event-driven PrEP among men who have sex with men

2020 ◽  
Vol 29-30 ◽  
pp. 100650
Author(s):  
Liza Coyer ◽  
Mark A M van den Elshout ◽  
Roel C A Achterbergh ◽  
Amy Matser ◽  
Maarten F Schim van der Loeff ◽  
...  
Keyword(s):  
Event Driven ◽  
Sex With Men ◽  
Exposure Prophylaxis

Incidence and duration of incident oropharyngeal gonorrhoea and chlamydia infections among men who have sex with men: prospective cohort study

2020 ◽  
pp. sextrans-2020-054764 ◽  
Author(s):  
Eric P F Chow ◽  
Lenka A Vodstrcil ◽  
Deborah A Williamson ◽  
Kate Maddaford ◽  
Jane S Hocking ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Median Duration ◽  
Prospective Cohort ◽  
Nucleic Acid Amplification ◽  
Oropharyngeal Infection ◽  
Duration Of Infection ◽  
Sex With Men ◽  
Exposure Prophylaxis

ObjectivesThis prospective cohort study aimed to determine the natural history and incidence of oropharyngeal gonorrhoea and chlamydia among a cohort of men who have sex with men (MSM) over a 12-week period, and to examine risk factors associated with incident oropharyngeal infections.MethodsMSM either aged ≥18 years and had a diagnosis of oropharyngeal gonorrhoea by nucleic acid amplification test (NAAT) in the past 3 months or aged 18–35 years who were HIV-negative taking pre-exposure prophylaxis (PrEP) were eligible for this study. Enrolled men were followed up for 12 weeks. Oropharyngeal swabs were collected at week 0 (baseline) and week 12 (end of study). Between these time points, weekly saliva specimens and the number of tongue kissing, penile–oral and insertive rimming partners were collected by post. Oropharyngeal swabs and saliva specimens were tested by NAAT for Neisseria gonorrhoeae and Chlamydia trachomatis. Poisson regression was performed to examine the risk factors (weekly number of partners) associated with incident oropharyngeal gonorrhoea.ResultsA total of 100 MSM were recruited. The incidence of oropharyngeal gonorrhoea and chlamydia was 62 (95% CI 37 to 105) and 9 (95% CI 2 to 35)/100 person-years, respectively. The median duration of incident oropharyngeal infection with gonorrhoea was 28 days (IQR=21–36, n=7). The incidence rate ratio (IRR) for oropharyngeal gonorrhoea increased with an increased number of kissing partners (IRR=1.08; 95% CI 1.03 to 1.12) an increased number of penile-oral sex partners (IRR=1.07, 95% CI 1.01 to 1.14) but not with an increased number of insertive rimming partners (IRR=1.11, 95% CI 0.96 to 1.29) or other demographic factors. The IRR and duration of incident oropharyngeal chlamydia were not calculated due to the small number of cases (n=2).ConclusionsMSM have a high incidence of oropharyngeal gonorrhoea and the median duration of infection was less than 3 months.

scholarly journals Men who have sex with men more often chose daily than event-driven use of pre-exposure prophylaxis: baseline analysis of a demonstration study in Amsterdam

2018 ◽  
Vol 21 (3) ◽  
pp. e25105 ◽  
Author(s):  
Elske Hoornenborg ◽  
Roel CA Achterbergh ◽  
Maarten F Schim van der Loeff ◽  
Udi Davidovich ◽  
Jannie J van der Helm ◽  
...  
Keyword(s):  
Event Driven ◽  
Sex With Men ◽  
Exposure Prophylaxis

High uptake of pre-exposure prophylaxis (PrEP) during early roll-out in Belgium: results from surveillance reports

Sexual Health ◽  
2019 ◽  
Vol 16 (1) ◽  
pp. 80 ◽  
Author(s):  
Bea Vuylsteke ◽  
Thijs Reyniers ◽  
Catherine Lucet ◽  
Christiana Nöstlinger ◽  
Jessika Deblonde ◽  
...  
Keyword(s):  
Disability Insurance ◽  
Aggregated Data ◽  
Increased Risk ◽  
Event Driven ◽  
Sub Saharan ◽  
Sex With Men ◽  
Hiv Acquisition ◽  
Risk Of Hiv Acquisition ◽  
Exposure Prophylaxis ◽  
Roll Out

Background Since 1 June 2017, oral pre-exposure prophylaxis (PrEP) could be prescribed and reimbursed in Belgium as prophylactic medication for people who are at increased risk of HIV acquisition. The aim of this study was to determine the uptake of daily and event-driven PrEP in Belgium during the first 9 months of roll-out. Methods: Routine aggregated data on the number of reimbursement requests and the number of boxes of Truvada (Gilead Sciences, Cambridge, UK) delivered for PrEP through the Belgian pharmacies were obtained from the National Institute for Health and Disability Insurance. We also collected aggregated data from seven Aids Reference Centres (ARCs) currently providing most of the PrEP care in Belgium. Results: From 1 June 2017 to 28 February 2018, 1352 requests for reimbursement were approved by the National Institute for Health and Disability Insurance. Almost 98% of those who bought at least one box of 30 tablets of emtricitabine 200mg/tenofovir disoproxil fumarate 300mg (FTC/TDF) in a Belgian pharmacy were male, and most (67%) were between 30 and 50 years of age. According to data obtained from ARCs, the proportion of those choosing event-driven PrEP initially ranged between 29% and 73%. Conclusions: The uptake of PrEP in Belgium since the start of the roll-out in June 2017 has been high, and almost entirely limited to men who have sex with men, of whom 43% initially prefer a non-daily regimen. A better understanding is needed as to why other populations, such as sub-Saharan African migrants, are not accessing PrEP, as well as the development of a more sustainable PrEP delivery model.

Transient Changes in Pre-Exposure Prophylaxis Use and Daily Sexual Behaviour after the Implementation of COVID-19 Restrictions Among Men Who Have Sex with Men

2020 ◽  
Author(s):  
Vita W. Jongen ◽  
Hanne M. L. Zimmermann ◽  
Anders Boyd ◽  
Elske Hoornenborg ◽  
Mark A. M. van den Elshout ◽  
...  
Keyword(s):  
Sexual Behaviour ◽  
Sex With Men ◽  
Exposure Prophylaxis
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