Transient Changes in Pre-Exposure Prophylaxis Use and Daily Sexual Behaviour after the Implementation of COVID-19 Restrictions Among Men Who Have Sex with Men

2020 ◽  
Author(s):  
Vita W. Jongen ◽  
Hanne M. L. Zimmermann ◽  
Anders Boyd ◽  
Elske Hoornenborg ◽  
Mark A. M. van den Elshout ◽  
...  
Keyword(s):  
Sexual Behaviour ◽  
Sex With Men ◽  
Exposure Prophylaxis

scholarly journals Pre-exposure prophylaxis' knowledge, attitudes, practices amongst italian men who have sex with men

2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
G Voglino ◽  
MR Gualano ◽  
S Rousset ◽  
F Bert ◽  
R Siliquini ◽  
...  
Keyword(s):  
Sexual Behaviour ◽  
Online Survey ◽  
Healthcare Personnel ◽  
Attitudes And Practices ◽  
Barriers To Access ◽  
Immunodeficiency Virus ◽  
High Infection ◽  
Sex With Men ◽  
Prep Awareness ◽  
Exposure Prophylaxis

Abstract Background Pre-exposure prophylaxis (PrEP) is suitable for human immunodeficiency virus (HIV)high-infection-risk people, foremost amongst males who have sex with other males (MSM). This study evaluated knowledge, attitudes and practices regarding PrEP in a sample of Italian MSM, in order to hypothesize strategies to implement PrEP awareness and use. Methods An online survey was given to an opportunistic sample of Italian MSM. The questionnaire investigated sexual behaviour, knowledge on HIV and PrEP awareness, attitudes and practices. Univariable and multivariable logistic regressions were conducted to identify possible associations with PrEP knowledge. Results A total of 196 MSM completed the survey. Overall data showed very good HIV and safe sexual behaviour knowledge (94.4% of correct answers). Nevertheless, our sample rarely used PrEP because of existing barriers: high therapy price (26.9%)and fear of side effects (23.8%). Only 10.3% of partecipants were informed on HIV and PReP by institutional channels, even less (7.5%) from specialized physicians and general practitioners. The most significant association with PrEP knowledge was having regular HIV-tests (adjusted odds ratio (AdjOR) = 3.16; confidence interval (CI) = 1.06-9.29); Conclusions PreP's Knowledge was well established, but PrEP use was not widespread. It is necessary to improve communication on PrEP and to lower existing barriers in order to grant access to PrEP access. Key messages Barriers to access PrEP have to be lowered. Healthcare personnel has to be involved in PrEP's benefits communication.

scholarly journals Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study

2017 ◽  
Vol 4 (9) ◽  
pp. e402-e410 ◽  
Author(s):  
Jean-Michel Molina ◽  
Isabelle Charreau ◽  
Bruno Spire ◽  
Laurent Cotte ◽  
Julie Chas ◽  
...  
Keyword(s):  
Cohort Study ◽  
Sexual Behaviour ◽  
Observational Cohort Study ◽  
On Demand ◽  
Observational Cohort ◽  
Sex With Men ◽  
Exposure Prophylaxis

scholarly journals Introducing pre-exposure prophylaxis to prevent HIV acquisition among men who have sex with men in Sweden: insights from a mathematical pair formation model

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e033852 ◽  
Author(s):  
Disa Hansson ◽  
Susanne Strömdahl ◽  
Ka Yin Leung ◽  
Tom Britton
Keyword(s):  
High Risk ◽  
Sexual Behaviour ◽  
Casual Sex ◽  
Pair Formation ◽  
Hiv Prevalence ◽  
Formation Model ◽  
Sex With Men ◽  
Exposure Prophylaxis ◽  
The Impact

ObjectivesSince 2017, the Public Health Agency of Sweden recommends that pre-exposure prophylaxis (PrEP) for HIV should be offered to high-risk individuals, in particular to men who have sex with men (MSM). The objective of this study is to develop a mathematical model investigating the effect of introducing PrEP to MSM in Sweden.DesignA pair formation model, including steady and casual sex partners, is developed to study the impact of introducing PrEP. Two groups are included in the model: sexually high active MSM and sexually low active MSM. Three mixing assumptions between the groups are considered.SettingA gay-friendly MSM HIV/sexually transmitted infection testing clinic in Stockholm, Sweden. This clinic started offering PrEP to MSM in October 2018.ParticipantsThe model is calibrated according to detailed sexual behaviour data gathered in 2015 among 403 MSM.ResultsBy targeting sexually high active MSM, a PrEP coverage of 3.5% of the MSM population (10% of all high actives) would result in the long-term HIV prevalence to drop considerably (close to 0%). While targeting only low actives would require a PrEP coverage of 35% for a similar reduction. The main effect of PrEP is the reduced susceptibility, whereas the increased HIV testing rate (every third month) among PrEP users plays a lesser role.ConclusionsTo create a multifaceted picture of the effects of interventions against HIV, we need models that include the different stages of HIV infection and real-world data on detailed sexual behaviour to calibrate the mathematical models. Our findings conclude that targeting HIV high-risk individuals, within HIV risk populations such as MSM, with PrEP programmes could greatly decrease the long-term HIV prevalence in Sweden. Therefore, risk stratification of individuals is of importance in PrEP implementation programmes, to ensure optimising the effect and cost-effectiveness of such programmes.

Quantifying heterogeneity in sexual behaviour and distribution of STIs before and after pre-exposure prophylaxis among men who have sex with men

2021 ◽  
pp. sextrans-2021-055227
Author(s):  
Daphne Amanda van Wees ◽  
Sophie Diexer ◽  
Ganna Rozhnova ◽  
Amy Matser ◽  
Chantal den Daas ◽  
...  
Keyword(s):  
High Risk ◽  
Risk Score ◽  
Sexual Behaviour ◽  
Sti Prevention ◽  
Gini Coefficients ◽  
Before And After ◽  
High Risk Sexual Behaviour ◽  
Sex With Men ◽  
Exposure Prophylaxis ◽  
The Impact

Objectives: Pre-exposure prophylaxis (PrEP) use may influence sexual behaviour and transmission of STIs among men who have sex with men (MSM). We aimed to quantify the distribution of STI diagnoses among MSM in the Netherlands based on their sexual behaviour before and after the introduction of PrEP.Methods: HIV-negative MSM participating in a prospective cohort study (Amsterdam Cohort Studies) completed questionnaires about sexual behaviour and were tested for STI/HIV during biannual visits (2009–2019). We developed a sexual behaviour risk score predictive of STI diagnosis and used it to calculate Gini coefficients for gonorrhoea, chlamydia and syphilis diagnoses in the period before (2009 to mid-2015) and after PrEP (mid-2015 to 2019). Gini coefficients close to zero indicate that STI diagnoses are homogeneously distributed over the population, and close to one indicate that STI diagnoses are concentrated in individuals with a higher risk score.Results: The sexual behaviour risk score (n=630, n visits=10 677) ranged between 0.00 (low risk) and 3.61 (high risk), and the mean risk score increased from 0.70 (SD=0.66) before to 0.93 (SD=0.80) after PrEP. Positivity rates for chlamydia (4%) and syphilis (1%) remained relatively stable, but the positivity rate for gonorrhoea increased from 4% before to 6% after PrEP. Gini coefficients increased from 0.37 (95% CI 0.30 to 0.43) to 0.43 (95% CI 0.36 to 0.49) for chlamydia, and from 0.37 (95% CI 0.19 to 0.52) to 0.50 (95% CI 0.32 to 0.66) for syphilis comparing before to after PrEP. The Gini coefficient for gonorrhoea remained stable at 0.46 (95% CI 0.40 to 0.52) before and after PrEP.Conclusions: MSM engaged in more high-risk sexual behaviour and gonorrhoea diagnoses increased after PrEP was introduced. Chlamydia and syphilis diagnoses have become more concentrated in a high-risk subgroup. Monitoring the impact of increasing PrEP coverage on sexual behaviour and STI incidence is important. Improved STI prevention is needed, especially for high-risk MSM.

Sign in / Sign up

Export Citation Format

Share Document