scholarly journals Strategies used by gay male HIV serodiscordant couples to reduce the risk of HIV transmission from anal intercourse in three countries

2019 ◽  
Vol 22 (4) ◽  
pp. e25277 ◽  
Author(s):  
Benjamin R Bavinton ◽  
Garrett P Prestage ◽  
Fengyi Jin ◽  
Nittaya Phanuphak ◽  
Beatriz Grinsztejn ◽  
...  
Keyword(s):  
Hiv Transmission ◽  
Anal Intercourse ◽  
Serodiscordant Couples ◽  
Gay Male ◽  
Hiv Serodiscordant Couples

Condom effectiveness in reducing heterosexual HIV transmission: a systematic review and meta-analysis of studies on HIV serodiscordant couples

2015 ◽  
Vol 16 (4) ◽  
pp. 489-499 ◽  
Author(s):  
Foteini K Giannou ◽  
Chrissa G Tsiara ◽  
Georgios K Nikolopoulos ◽  
Michael Talias ◽  
Vasiliki Benetou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hiv Transmission ◽  
Meta Analysis ◽  
Serodiscordant Couples ◽  
Hiv Serodiscordant Couples

scholarly journals Experiences With Safer Conception Services for HIV-Serodiscordant Couples at a Referral Hospital in Nairobi, Kenya

2021 ◽  
Vol 3 ◽  
Author(s):  
Anne Kaggiah ◽  
Grace Kimemia ◽  
Hellen Moraa ◽  
Peter Muiruri ◽  
John Kinuthia ◽  
...  
Keyword(s):  
Viral Load ◽  
Hiv Transmission ◽  
Healthcare Providers ◽  
Referral Hospital ◽  
Safer Conception ◽  
Serodiscordant Couples ◽  
Hiv Serodiscordant Couples ◽  
Viral Load Monitoring ◽  
Load Monitoring ◽  
Safer Conception Methods

Human immunodeficiency virus-serodiscordant couples are an important source of new HIV infections in Africa. When trying to conceive, uninfected partners may be at high risk of infection if the infected partner is not virally suppressed. Multiple strategies targeting safer conception exist, but these services are limited. However, when services are available and used, serodiscordant couples can be protected from HIV transmission, and safe to have children if desired. To successfully introduce, integrate, promote, and optimize the service delivery of safer conception with HIV care, it is crucial to understand how HIV-serodiscordant couples perceive and experience these services. Further, viral load monitoring can be critical to safer conception, but there is limited literature on how it informs the decision of the partners about conception. This qualitative study describes the knowledge, perceptions, and experiences of both safer conception services and viral load monitoring among 26 HIV-serodiscordant couples seeking safer conception care at a referral hospital in Nairobi, Kenya. In-depth interviews of HIV-serodiscordant couples were conducted from April to July 2017, and transcripts were analyzed to identify the themes central to the experience of safer conception services of couples and viral load monitoring. Serodiscordant couples reported success in using some of the safer conception methods and had positive experiences with healthcare providers. However, despite using the services, some were concerned about HIV transmission to the seronegative partner and baby, while others faced challenges when using pre-exposure prophylaxis (PrEP) and vaginal insemination. Overall, their motivation to have children overcame their concern about HIV transmission, and they welcomed discussions on risk reduction. Moreover, supportive clinic staff was identified as key to facilitating trust in safer conception methods. Furthermore, viral load monitoring was identified as integral to safer conception methods, an emerging theme that requires further evaluation, especially where routine viral load monitoring is not performed. In conclusion, healthcare providers offering safer conception services should build trust with couples, and recognize the need for continual couple counseling to encourage the adoption of safer conception services.

Safer conception options for HIV-serodiscordant couples

2012 ◽  
Vol 206 (1) ◽  
pp. e21 ◽  
Author(s):  
Deborah Cohan ◽  
Shannon Weber ◽  
Ronald Goldschmidt
Keyword(s):  
Safer Conception ◽  
Serodiscordant Couples ◽  
Hiv Serodiscordant Couples

Couple-Focused Interventions for HIV-Serodiscordant Couples During Transition to Motherhood

2011 ◽  
Vol 33 (2) ◽  
pp. 143-160 ◽  
Author(s):  
Marco Pereira ◽  
Frank M. Dattilio ◽  
Maria Cristina Canavarro ◽  
Isabel Narciso
Keyword(s):  
Serodiscordant Couples ◽  
Transition To Motherhood ◽  
Hiv Serodiscordant Couples

scholarly journals Formative Assessment of ARM-U: A Modular Intervention for Decreasing Risk Behaviors Among HIV-Positive and HIV-Negative Methamphetamine-Using MSM

2010 ◽  
Vol 4 (1) ◽  
pp. 105-115 ◽  
Author(s):  
Richard S Garfein ◽  
Mitcheal Metzner ◽  
Jazmine Cuevas ◽  
Chad A Bousman ◽  
Thomas Patterson
Keyword(s):  
Focus Groups ◽  
Risk Behaviors ◽  
Hiv Transmission ◽  
Anal Intercourse ◽  
Formative Research ◽  
Lessons Learned ◽  
Transmission Risk ◽  
Individual Risk ◽  
Satisfaction Survey ◽  
Methamphetamine Use

Background: Methamphetamine is a major contributor to HIV transmission among men who have sex with men (MSM). Recent studies show that up to one-third of methamphetamine-using MSM (MUMSM) inject the drug. We developed a behavioral intervention for MUMSM to decrease unprotected anal intercourse and increase awareness of parenteral HIV transmission risk. This 6-session (3 in-person, 3 by telephone) modular intervention was designed to be tailored to participants’ HIV (+/-) and injection drug user ([IDU] yes/no) status. We present results of formative research used to evaluate the content and to assess feasibility and acceptability of this individual-level HIV risk-reduction intervention. Setting: HIV research clinic in a high MSM and methamphetamine prevalence neighborhood. Project: Avoiding Risks from Methamphetamine-Use (ARM-U) is a brief toolbox intervention that allows counselors to select modules that suit a client’s individual risk profile and intervention needs employing motivational interviewing and cognitive behavioral theory. We evaluated the format and content of the intervention through focus groups and pre-testing of the entire intervention using volunteers from the target population stratified into four groups (HIV+/IDU, HIV-/IDU, HIV+/non-IDU, HIV-/non-IDU). Four individuals in each stratum were recruited to undergo the intervention and complete a satisfaction survey at the end of each in-person session. Results: In total, 25 MUMSM attended one of five focus groups. Participants thought all proposed intervention topics were important and could aid in reducing sexual risk behaviors among MUMSM. However, the neurocognitive effects of methamphetamine were reported to be a barrier to practicing safer sex, condom use negotiation or HIV status disclosure. Fifteen (94%) of 16 participants completed all 6 sessions and the satisfaction survey. On average, participants felt the intervention was useful for MUMSM, made them contemplate and move toward behavior change, and would recommend the program to their peers. Lessons Learned: Based on our formative research, we revised the ARM-U intervention to emphasize pre-planning to avoid combining methamphetamine use and sex or develop strategies to avoid sex risk following methamphetamine use. We also increased emphasis on referrals for care and other requested services. Future efficacy trials are needed to evaluate the intervention’s ability to reduce HIV-associated risk behaviors.

scholarly journals Pre-exposure prophylaxis for HIV-negative persons with partners living with HIV: uptake, use, and effectiveness in an open-label demonstration project in East Africa

2018 ◽  
Vol 1 ◽  
pp. 3 ◽  
Author(s):  
Renee Heffron ◽  
Kenneth Ngure ◽  
Josephine Odoyo ◽  
Nulu Bulya ◽  
Edna Tindimwebwa ◽  
...  
Keyword(s):  
Hiv Infections ◽  
Hiv Treatment ◽  
Demonstration Project ◽  
Hiv Incidence ◽  
Serodiscordant Couples ◽  
Treatment Services ◽  
Hiv Serodiscordant Couples ◽  
Exposure Prophylaxis ◽  
Living With Hiv ◽  
Hiv Negative

Background: Pre-exposure prophylaxis (PrEP) can provide high protection against HIV infection and is a recommended intervention for HIV-negative persons with substantial HIV risk.  Demonstration projects conducted in diverse settings worldwide illustrate practical examples of how PrEP can be delivered. This manuscript presents estimates of effectiveness and patterns of PrEP use within a two-year demonstration project of PrEP for HIV-negative members of heterosexual HIV serodiscordant couples in East Africa. Methods: The PrEP delivery model integrated PrEP into HIV treatment services, prioritizing PrEP use for HIV-negative partners within serodiscordant couples before and during the first 6 months after the partner living with HIV initiated antiretroviral therapy (ART).  We measured PrEP uptake through pharmacy records and adherence to PrEP through medication event monitoring system (MEMS) bottle caps and quantification of tenofovir in plasma among a random sample of participants. We estimated HIV infections prevented using a counterfactual cohort simulated from the placebo arm of a previous PrEP clinical trial. Results: We enrolled 1,010 HIV serodiscordant couples that were naïve to ART and PrEP.  Ninety-seven percent of HIV-negative partners initiated PrEP. Objective measures suggest high adherence: 71% of HIV-negative participants took ≥80% of expected doses, as recorded via MEMS, and 81% of plasma samples had tenofovir detected.  Four incident HIV infections were observed (incidence rate=0.24 per 100 person-years), a 95% reduction (95% CI 86-98%, p<0.0001) in HIV incidence, relative to estimated HIV incidence for the population in the absence of PrEP integrated into HIV treatment services.   Conclusions: PrEP uptake and adherence were high and incident HIV was rare in this PrEP demonstration project for African HIV-negative individuals whose partners were known to be living with HIV.  Delivery of PrEP to HIV-negative partners within HIV serodiscordant couples was feasible and should be prioritized for wide-scale implementation.

scholarly journals A scoping review and thematic analysis of social and behavioural research among HIV-serodiscordant couples in high-income settings

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Joshua B Mendelsohn ◽  
Liviana Calzavara ◽  
Amrita Daftary ◽  
Sanjana Mitra ◽  
Joel Pidutti ◽  
...  
Keyword(s):  
Thematic Analysis ◽  
Scoping Review ◽  
High Income ◽  
Serodiscordant Couples ◽  
Hiv Serodiscordant Couples ◽  
Behavioural Research

scholarly journals Commentary: Probability of HIV transmission through anal intercourse

2010 ◽  
Vol 39 (4) ◽  
pp. 1064-1065 ◽  
Author(s):  
A. E. Grulich ◽  
I. Zablotska
Keyword(s):  
Hiv Transmission ◽  
Anal Intercourse
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