Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells

Cho Hee Kim; Song Iy Han; Su Yeon Lee; Hyun Suk Youk; Ji Young Moon; Hong Quan Duong; Min Jung Park; Young Mi Joo; Hye Gyeong Park; Yung Jin Kim; Mi Ae Yoo; Sung-Chul Lim; Ho Sung Kang

doi:10.1002/jcp.20941

Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells

Journal of Cellular Physiology ◽

10.1002/jcp.20941 ◽

2007 ◽

Vol 211 (2) ◽

pp. 371-385 ◽

Cited By ~ 31

Author(s):

Cho Hee Kim ◽

Song Iy Han ◽

Su Yeon Lee ◽

Hyun Suk Youk ◽

Ji Young Moon ◽

...

Keyword(s):

Lung Cancer ◽

Reactive Oxygen Species ◽

Reactive Oxygen Species Production ◽

Signal Pathway ◽

Superoxide Dismutases ◽

Oxygen Species ◽

Glucose Depletion ◽

Kinase C ◽

Species Production ◽

A549 Lung

Download Full-text

Genipin enhances the antitumor effect of elesclomol in A549 lung cancer cells by blocking uncoupling protein‑2 and stimulating reactive oxygen species production

Oncology Letters ◽

10.3892/ol.2020.12237 ◽

2020 ◽

Vol 20 (6) ◽

pp. 1-1

Author(s):

Jin Hee Lee ◽

Young Seok Cho ◽

Kyung-Ho Jung ◽

Jin Won Park ◽

Kyung-Han Lee

Keyword(s):

Lung Cancer ◽

Reactive Oxygen Species ◽

Cancer Cells ◽

Reactive Oxygen Species Production ◽

Antitumor Effect ◽

Uncoupling Protein ◽

Uncoupling Protein 2 ◽

Oxygen Species ◽

Species Production ◽

A549 Lung

Download Full-text

N-Butanol Subfraction of Brassica Rapa L. Promotes Reactive Oxygen Species Production and Induces Apoptosis of A549 Lung Adenocarcinoma Cells via Mitochondria-Dependent Pathway

Molecules ◽

10.3390/molecules23071687 ◽

2018 ◽

Vol 23 (7) ◽

pp. 1687

Author(s):

Adila Aipire ◽

Qiuyan Chen ◽

Shanshan Cai ◽

Jinyu Li ◽

Changshuang Fu ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Lung Adenocarcinoma ◽

Brassica Rapa ◽

Reactive Oxygen Species Production ◽

Oxygen Species ◽

Adenocarcinoma Cells ◽

Lung Adenocarcinoma Cells ◽

Species Production ◽

Dependent Pathway ◽

A549 Lung

Download Full-text

Fengycin inhibits the growth of the human lung cancer cell line 95D through reactive oxygen species production and mitochondria-dependent apoptosis

Anti-Cancer Drugs ◽

10.1097/cad.0b013e3283611395 ◽

2013 ◽

pp. 1 ◽

Cited By ~ 10

Author(s):

Hongping Yin ◽

Chuanlong Guo ◽

Ying Wang ◽

Dan Liu ◽

Yunbin Lv ◽

...

Keyword(s):

Lung Cancer ◽

Reactive Oxygen Species ◽

Reactive Oxygen Species Production ◽

Human Lung ◽

Cancer Cell Line ◽

Lung Cancer Cell Line ◽

Human Lung Cancer ◽

Oxygen Species ◽

Lung Cancer Cell ◽

Species Production

Download Full-text

Increased Reactive Oxygen Species Production by Alveolar Macrophages from Malignant Lobe of Lung Cancer Patients.

Journal of Clinical Biochemistry and Nutrition ◽

10.3164/jcbn.22.183 ◽

1997 ◽

Vol 22 (3) ◽

pp. 183-191 ◽

Cited By ~ 1

Author(s):

Rashmi N. SHARMA ◽

Digamber BEHERA ◽

Krishan L. KHANDUJA

Keyword(s):

Lung Cancer ◽

Reactive Oxygen Species ◽

Cancer Patients ◽

Alveolar Macrophages ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Oxygen Species ◽

Lung Cancer Patients ◽

Species Production

Download Full-text

P2-123: Induction of apoptosis by rhein via reactive oxygen species production, GADD153 expression, and caspase-3 activation in human lung cancer A-549 cells

Journal of Thoracic Oncology ◽

10.1097/01.jto.0000283587.17491.00 ◽

2007 ◽

Vol 2 (8) ◽

pp. S540

Author(s):

Te-Chun Hsia ◽

Liang-Wen Hang ◽

Jing-Gung Chung

Keyword(s):

Lung Cancer ◽

Reactive Oxygen Species ◽

Reactive Oxygen Species Production ◽

Caspase 3 ◽

Human Lung ◽

Human Lung Cancer ◽

Oxygen Species ◽

Induction Of Apoptosis ◽

Species Production ◽

Gadd153 Expression

Download Full-text

Expression of heme oxygenase-1 mediated by non-NMDA and metabotropic receptors in glial cells: possible involvement of reactive oxygen species production and protein kinase C activation

Neuropharmacology ◽

10.1016/s0028-3908(99)00020-9 ◽

1999 ◽

Vol 38 (6) ◽

pp. 825-834 ◽

Cited By ~ 14

Author(s):

Yasuji Matsuoka ◽

Yoshihisa Kitamura ◽

Jun-Ichi Kakimura ◽

Takashi Taniguchi

Keyword(s):

Reactive Oxygen Species ◽

Protein Kinase C ◽

Protein Kinase ◽

Reactive Oxygen Species Production ◽

Heme Oxygenase 1 ◽

Oxygen Species ◽

Metabotropic Receptors ◽

Kinase C ◽

Species Production ◽

Protein Kinase C Activation

Download Full-text

Peneciraistin C induces caspase-independent autophagic cell death through mitochondrial-derived reactive oxygen species production in lung cancer cells

Cancer Science ◽

10.1111/cas.12253 ◽

2013 ◽

Vol 104 (11) ◽

pp. 1476-1482 ◽

Cited By ~ 10

Author(s):

Xiaohong Pan ◽

Desheng Liu ◽

Juan Wang ◽

Xiuli Zhang ◽

Miaomiao Yan ◽

...

Keyword(s):

Lung Cancer ◽

Reactive Oxygen Species ◽

Cell Death ◽

Cancer Cells ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Autophagic Cell Death ◽

Lung Cancer Cells ◽

Oxygen Species ◽

Species Production

Download Full-text

Oestrogen-related receptor alpha inverse agonist XCT-790 arrests A549 lung cancer cell population growth by inducing mitochondrial reactive oxygen species production

Cell Proliferation ◽

10.1111/j.1365-2184.2009.00659.x ◽

2010 ◽

Vol 43 (2) ◽

pp. 103-113 ◽

Cited By ~ 31

Author(s):

J. Wang ◽

Y. Wang ◽

C. Wong

Keyword(s):

Lung Cancer ◽

Reactive Oxygen Species Production ◽

Oxygen Species ◽

Mitochondrial Reactive Oxygen Species ◽

Lung Cancer Cell ◽

A549 Lung Cancer Cell ◽

Cell Population Growth ◽

Cancer Cell Population ◽

Species Production ◽

A549 Lung

Download Full-text

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

Diabetes ◽

10.2337/diabetes.49.11.1939 ◽

2000 ◽

Vol 49 (11) ◽

pp. 1939-1945 ◽

Cited By ~ 1000

Author(s):

T. Inoguchi ◽

P. Li ◽

F. Umeda ◽

H. Y. Yu ◽

M. Kakimoto ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Protein Kinase C ◽

Fatty Acid ◽

Free Fatty Acid ◽

Protein Kinase ◽

Reactive Oxygen Species Production ◽

Oxygen Species ◽

Kinase C ◽

High Glucose Level ◽

Species Production

Download Full-text

Mitochondrial activity and reactive oxygen species production define distinct subpopulations of human sperm with different functional properties

Reproduction Abstracts ◽

10.1530/repabs.1.p012 ◽

2014 ◽

Author(s):

Joao Ramalho-Santos ◽

Monica Marques ◽

Artur Paiva ◽

Teresa Almeida-Santos ◽

Ana Paula Sousa

Keyword(s):

Reactive Oxygen Species ◽

Functional Properties ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Human Sperm ◽

Mitochondrial Activity ◽

Oxygen Species ◽

Species Production

Download Full-text