scholarly journals Increased Reactive Oxygen Species Production by Alveolar Macrophages from Malignant Lobe of Lung Cancer Patients.

1997 ◽  
Vol 22 (3) ◽  
pp. 183-191 ◽  
Author(s):  
Rashmi N. SHARMA ◽  
Digamber BEHERA ◽  
Krishan L. KHANDUJA
Keyword(s):  
Lung Cancer ◽  
Reactive Oxygen Species ◽  
Cancer Patients ◽  
Alveolar Macrophages ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Lung Cancer Patients ◽  
Species Production

β-Adrenergic receptor function and oxygen radical production in bovine pulmonary alveolar macrophages

1988 ◽  
Vol 66 (12) ◽  
pp. 1538-1541 ◽  
Author(s):  
P. D. Conlon ◽  
P. O. Ogunbiyi ◽  
W. D. Black ◽  
P. Eyre
Keyword(s):  
Reactive Oxygen Species ◽  
Alveolar Macrophages ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Inhibitory Effects ◽  
Ici 118,551 ◽  
Oxygen Radical Production ◽  
Pulmonary Alveolar Macrophages ◽  
Species Production

Reactive oxygen species production by bovine pulmonary alveolar macrophages was evaluated by a chemiluminescence assay utilizing luminol and opsonized zymosan. Incubation with dobutamine (5 × 10−8 and 5 × 10−7 M) or isoproterenol (5 × 10−8 and 5 × 10−7 M) prior to zymosan challenge significantly (p < 0.05) increased the time for chemiluminescence to begin, and significantly decreased the level of maximum chemiluminescence. The agonists' inhibitory effects on maximum chemiluminescence were significantly reduced by pre-incubation with the appropriate antagonist (atenolol at 1 × 10−6 M for dobutamine; and propranolol at 1 × 10−6 M for isoproterenol). Salbutamol at 1 × 10−6 M significantly reduced the level of maximum chemiluminescence only, but did not increase the time for chemiluminescence to begin. This effect was significantly reduced by the presence of the β2-antagonist ICI 118,551 at 1 × 10−6 M. The results reveal the presence of (β1- and (β2-adrenoceptors on bovine pulmonary alveolar macrophages, and suggest that these receptors are important in the regulation of reactive oxygen species production by these cells.

scholarly journals Study of the Mechanisms Associated with PM2.5 Induced Reactive Oxygen Species Production in Alveolar Macrophages

2020 ◽  
Vol 118 (3) ◽  
pp. 450a
Author(s):  
David Flores ◽  
Micah B. Olivas ◽  
Mandeep Kaur ◽  
Kosha Raval ◽  
Joel Castillo ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Alveolar Macrophages ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Species Production
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