scholarly journals Influence of Oral Contraceptive Pills on Homocysteine and Nitric Oxide Levels: As Risk Factors for Cardiovascular Disease

2012 ◽  
Vol 26 (2) ◽  
pp. 120-123 ◽  
Author(s):  
Soudabeh Fallah ◽  
Vajihe Nouroozi ◽  
Morteza Seifi ◽  
Ali Samadikuchaksaraei ◽  
Elaheh Mokhtarned Aghdashi
2021 ◽  
Vol 7 (2) ◽  
Author(s):  
Nadia N. Osman ◽  
Dalal Mhammed Al-Mutairi

Objective: The aim of this study was to evaluate the effect of oral contraceptive pills on oxidative stress in Saudi women. Methods: A total of fifty-five Saudi women were divided into two groups: users of oral contraceptive pills (OCP, N=30) for at least one year and non-users (NOCP, N=25). The demographic data were obtained through face-to-face interviews performed by the researcher. Blood specimen from both groups were drawn after 8 hours of fasting to estimate serum Total antioxidant (TAOC), Nitric oxide (NO), C-reactive protein (CRP), vitamins (E, B6, B12) and some hematological parameters: hemoglobin (Hb), Red blood cell (RBC), White blood cell (WBC). Results: The results showed a significant decreased in serum TAOC, NO, vitamins E and B6 accompanied with high significant increase in CRP level while no significant changes B12, HB, RBC and WBC were observed in the OCP users as compared to the control group. Conclusion: The results of this study indicated that the use of OCP resulted in low levels of the total antioxidant, nitric oxide, vitamin E, and B6 with a significant increase in CRP. Women who used OCP may be more susceptible to oxidative stress by enhanced depletion of antioxidants.


2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Maria Mironova ◽  
Mohammed K. Mahdi ◽  
Jyoti Bhatia ◽  
Rosemarie C. Nielson ◽  
Cataldo Doria

Introduction. Hepatic adenoma is an uncommon benign liver tumor presenting as solitary lesions or even rarely as hepatic adenomatosis. Large lesions carry a risk of rupture, hemorrhage, and malignant transformation. This case report aims to increase awareness about risk factors for hepatic adenomas, considering the increasing prevalence of obesity and the widespread use of oral contraceptive pills. Case Presentation. A 20-year-old obese female who was taking oral contraceptive pills for seven years presented to the emergency department with vomiting and abdominal pain caused by gastroenteritis. On imaging, multiple hepatic adenomas, including two lesions 6 and 9 cm in diameter, were incidentally found. During the hospitalization, the patient suddenly developed acute anemia and rupture of the largest lesion, which was promptly treated with arterial embolization. Discussion. Obesity and exposure to hormones are well-known risk factors for hepatic adenomas. The incidence of hepatic adenomas is steadily increasing because of the prevalence of obesity, especially among females. Lifestyle interventions for weight loss and discontinuation of oral contraceptive pills are considered a conservative treatment of hepatic adenomas. Large lesions possess the risk of malignant transformation and rupture and require surgical excision.


2011 ◽  
Vol 152 (36) ◽  
pp. 1447-1449
Author(s):  
Zsuzsa Krasznai ◽  
Péter Tóth

Oral hormonal contraceptives are the safest methods for young patients to avoid unwanted pregnancy. They are well accepted and have certain beneficial effects; however, physicians should pay attention to risk factors even when applied in young age. Obesity, dyslipidemia, smoking and oral contraceptive pills alone or in combination may lead to serious adverse events. Authors present a young woman who developed acute myocardial infarction in association with several unconsidered risk factors including the use of contraceptive pills. Orv. Hetil., 2011, 152, 1447–1449.


2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sameerah Mustafa ◽  
Asal Tawfeeq ◽  
Hadeel Hasan

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.


2020 ◽  
Vol 35 (3) ◽  
Author(s):  
Tayyaba Gul Malik ◽  
Hina Nadeem ◽  
Eiman Ayesha ◽  
Rabail Alam

Objective: To study the effect of short-term use of oral contraceptive pills on intra-ocular pressures of women of childbearing age.   Methods: It was a comparative observational study, conducted at Arif memorial teaching hospital and Allied hospital Faisalabad for a period of six months. Hundred female subjects were divided into two groups of 50 each. Group A, included females, who had been taking oral contraceptive pills (OCP) for more than 6 months and less than 36 months. Group B, included 50 age-matched controls, who had never used OCP. Ophthalmic and systemic history was taken. Careful Slit lamp examination was performed and intraocular pressures (IOP) were measured using Goldman Applanation tonometer. Fundus examination was done to rule out any posterior segment disease. After collection of data, we analyzed and compared the intra ocular pressures between the two groups by using ANOVA in SPSS version 21.   Results: Average duration of using OCP was 14.9 months. There was no significant difference of Cup to Disc ratios between the two groups (p= 0.109). However, significant difference was noted between the IOP of OCP group and controls. (p=0.000). Conclusion: OCP significantly increase IOP even when used for short time period.


1991 ◽  
Vol 29 (7) ◽  
pp. 28-28

We note an important correction to which the CMO, Health Trends and Prescribers Journal have already drawn attention. The first sentence of section 2.3.14 (p 37) should read “If any pill is omitted from the 21 days of active pills, additional contraception (barriers and spermicides) should be used for the 7 days after the pill(s) has been missed”.


2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Samuel Kusheta Katama ◽  
Desalegn Tsegaw Hibstu

Family planning is known not only as a fundamental intervention for improving the health of women but also as a human right. The aim of this study was to assess the current knowledge, attitude and practice of contraceptive use among female students in Dilla secondary and preparatory school, Dilla, South Ethiopia, 2014. A cross sectional study was conducted among 288 female students in Dilla secondary and preparatory school, south Ethiopia, June 19- 29/2014. A simple random sampling technique was used to select the study subjects. The data was collected using a self-administered structured questionnaire. The data was analyzed by SPSS 20. Chi-square test was used to identify associated factors. A total of 263 female students were involved in this study, of which 249 (94.7%) had good knowledge about contraception. The three most frequently identified methods were injectable form (83.9%), oral contraceptive pills (72.7%) and condom (48.6%). A total of 15.7% respondents ever used contraceptive. Among the users, 56.4% used oral contraceptive pills, and 23.1 and 10.2% used injectable form and condom, respectively. In spite of the fact that most respondents had good knowledge of contraception, their attitude and practice was low. Emphasis needs to be given on disseminating health information concerning the attitude and practice of contraceptive method.


Cancer ◽  
2002 ◽  
Vol 99 (2) ◽  
pp. 75-82 ◽  
Author(s):  
Carl Morrison ◽  
Patricia Prokorym ◽  
Clara Piquero ◽  
Paul E. Wakely ◽  
Gerard J. Nuovo

Sign in / Sign up

Export Citation Format

Share Document