scholarly journals Myocardial infarction associated with oral contraceptive use, smoking and elevated cholesterol level in a young patient

2011 ◽  
Vol 152 (36) ◽  
pp. 1447-1449
Author(s):  
Zsuzsa Krasznai ◽  
Péter Tóth

Oral hormonal contraceptives are the safest methods for young patients to avoid unwanted pregnancy. They are well accepted and have certain beneficial effects; however, physicians should pay attention to risk factors even when applied in young age. Obesity, dyslipidemia, smoking and oral contraceptive pills alone or in combination may lead to serious adverse events. Authors present a young woman who developed acute myocardial infarction in association with several unconsidered risk factors including the use of contraceptive pills. Orv. Hetil., 2011, 152, 1447–1449.

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Samuel Kusheta Katama ◽  
Desalegn Tsegaw Hibstu

Family planning is known not only as a fundamental intervention for improving the health of women but also as a human right. The aim of this study was to assess the current knowledge, attitude and practice of contraceptive use among female students in Dilla secondary and preparatory school, Dilla, South Ethiopia, 2014. A cross sectional study was conducted among 288 female students in Dilla secondary and preparatory school, south Ethiopia, June 19- 29/2014. A simple random sampling technique was used to select the study subjects. The data was collected using a self-administered structured questionnaire. The data was analyzed by SPSS 20. Chi-square test was used to identify associated factors. A total of 263 female students were involved in this study, of which 249 (94.7%) had good knowledge about contraception. The three most frequently identified methods were injectable form (83.9%), oral contraceptive pills (72.7%) and condom (48.6%). A total of 15.7% respondents ever used contraceptive. Among the users, 56.4% used oral contraceptive pills, and 23.1 and 10.2% used injectable form and condom, respectively. In spite of the fact that most respondents had good knowledge of contraception, their attitude and practice was low. Emphasis needs to be given on disseminating health information concerning the attitude and practice of contraceptive method.


2019 ◽  
Vol 6 (1) ◽  
pp. 10-13
Author(s):  
Kashefa Khatun ◽  
Shamsun Nahar ◽  
Abida Sultana ◽  
Shahnur Chisty ◽  
Asma Rumanaz Shahid ◽  
...  

Background: Long duration use of hormonal contraceptives can cause different metabolic effects. Objective: The purpose for the present study was to see the relationship between long duration of use of hormonal contraceptives and serum lipid profiles. Methodology: This cross-sectional study was carried out in the Department of Obstetrics & Gynaecology in collaboration with the Biochemistry Department at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2004 to December 2005 for eighteen (18) months. Women of reproductive age group who had given the history of taking low-dose oral contraceptive pills (OCP) containing 30 meg ethinyloestradiol (EE) plus 150 meg levonorgestrel (LNG) were included as study population. The women were divided into group A which was consisted of women who were using OCP for up to 5 years and group B who were using OCP for more than 5 years. Blood was collected from each woman in fasting state and serum was sent for estimation of serum lipids profiles like serum triglycerides, total cholesterol, LDL and HDL. Result: The women in group A was consisted of 20 women and the rest 20 women were in group B. Comparison of mean age between control and case groups showed no significant difference (31.75±4.85 vs 30.43±5.44 years). In women using OCP ≤5 years and >5 years, the mean (±SD) cholesterol levels were 252.50±48.86 and 239.55±48.73 mg/dl (p>0.10), triglyceride levels were 204.30±48.10 and 191.45±67.89 mg/dL (p>0.10), HDL levels were 42.82±8.96 and 43.00±6.46 (p>0.10) and LDL levels were 168.83±50.82 and 158.26±50.32 (p>0.10) respectively. Conclusion: The level of total cholesterol and triglycerides are not significantly varied with long duration (more than 5 years) of oral contraceptive pills use. Journal of Current and Advance Medical Research 2019;6(1):10-13


Blood ◽  
2021 ◽  
Vol 138 (Supplement 1) ◽  
pp. 4939-4939
Author(s):  
Princess Diana Sarmiento ◽  
Mervyn A. Sahud ◽  
Edward C.C. Wong

Abstract Background: Venous thromboembolism (VTE) is one of the most common cardiovascular disorders after myocardial infarction and stroke. Primary manifestations include deep vein thrombosis and pulmonary embolism, which are often preventable and often underdiagnosed. Patients with inherited thrombophilia or family history of VTE are at increased risk for VTE. Acquired VTE risk factors include the use of oral hormonal contraceptives, such as combined oral contraceptive pills (COCPs) containing estrogen and progestin. Women with a family history of VTE are advised not to take COCPs; possible alternatives include use of progestin-only contraceptive pills or non-oral contraceptive methods. Currently it is unknown if young women at college are given information regarding this potential risk when seeking oral contraceptives. Thus, higher education websites can provide a potential venue to promote awareness of this risk. In this study, we reviewed a sample of higher education websites in the US to assess availability of information on oral hormonal contraceptives and their risks for young women. Methods: US higher education institutions for this survey and categorized into 5 major types: community colleges, liberal arts institutions, private for-profit institutions, public non-profit institutions, and private non-profit institutions; 25 institutions from each category were included for analysis. The study was conducted using the Google search terms "birth control pills," "oral contraceptive pills," OR plus the university name. Mention of contraindications, risk factors, and blood clot warnings was noted for each website and categorized as to whether the information appeared on the institution's webpage or as a link to an external reference source. Information listed was further classified by risk factors and contraindications mentioned. Results: A total of 125 US higher education institution websites were assessed. Eighteen (14.4%) of the 125 offered information on COCP-related clotting risks. Community colleges and private, for-profit institutions had no information on birth control available either on their webpage or through an external link. Only 3 of 25 (12%) liberal arts institutions discussed clotting risk information. Five of the 25 (20%) public, nonprofit institutions surveyed provided information on their student webpages; three of these 5 offering information through their website as well as through a link to an external website. Of the private, non-profit institutions surveyed, 2 (8%) provided information through their institution's website and 4 (16%) provided information through external sources. Regarding contraindications, 2 (8%) liberal arts schools provided information on their website only, identical to the percentages seen with private and public non-profit institutions. Additionally, 4 (16%) private non-profit universities and 2 (8%) public, non-profit institutions provided information only through external sources. Two (8%) public non-profit institutions provided information both on their website and through external links. Overall, only 6 (4.8%) of the 125 institutions described family history or inherited prothrombotic blood disorder as a potential contraindication or risk factor for COCP-related clotting, all 6 of which were public or private non-profit institutions. Conclusion: The results of this study raise the question of whether higher education institutions are providing the appropriate risk and contraindication information for women considering oral contraceptives as a birth control method. This suggests that there is an opportunity for more birth control education to be provided by higher education institutions. Figure 1 Figure 1. Disclosures Sarmiento: Quest Diagnostics: Current Employment. Sahud: Quest Diagnostics: Current Employment. Wong: Quest Diagnostics: Current Employment, Current equity holder in publicly-traded company, Current holder of individual stocks in a privately-held company, Current holder of stock options in a privately-held company.


2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Maria Mironova ◽  
Mohammed K. Mahdi ◽  
Jyoti Bhatia ◽  
Rosemarie C. Nielson ◽  
Cataldo Doria

Introduction. Hepatic adenoma is an uncommon benign liver tumor presenting as solitary lesions or even rarely as hepatic adenomatosis. Large lesions carry a risk of rupture, hemorrhage, and malignant transformation. This case report aims to increase awareness about risk factors for hepatic adenomas, considering the increasing prevalence of obesity and the widespread use of oral contraceptive pills. Case Presentation. A 20-year-old obese female who was taking oral contraceptive pills for seven years presented to the emergency department with vomiting and abdominal pain caused by gastroenteritis. On imaging, multiple hepatic adenomas, including two lesions 6 and 9 cm in diameter, were incidentally found. During the hospitalization, the patient suddenly developed acute anemia and rupture of the largest lesion, which was promptly treated with arterial embolization. Discussion. Obesity and exposure to hormones are well-known risk factors for hepatic adenomas. The incidence of hepatic adenomas is steadily increasing because of the prevalence of obesity, especially among females. Lifestyle interventions for weight loss and discontinuation of oral contraceptive pills are considered a conservative treatment of hepatic adenomas. Large lesions possess the risk of malignant transformation and rupture and require surgical excision.


2012 ◽  
Vol 26 (2) ◽  
pp. 120-123 ◽  
Author(s):  
Soudabeh Fallah ◽  
Vajihe Nouroozi ◽  
Morteza Seifi ◽  
Ali Samadikuchaksaraei ◽  
Elaheh Mokhtarned Aghdashi

2019 ◽  
Vol 2 ◽  
pp. 251581631985600
Author(s):  
Kuan-Po Peng ◽  
Arne May

Background: Hormonal changes in natural menstrual cycles are known to modulate and even worsen headache symptoms in migraineurs; however, the impact of oral contraceptive pills (OCP), including combined oral contraceptive (COC) and progestogen-only pills on migraine symptomatology, is little investigated. Method: In this retrospective cohort study of 1758 migraine patients, data from 1032 female patients aged 15–45 years were accessed and their contraceptive methods, if any, were analyzed. Further comparisons were conducted between patients with OCP use and those without OCP use regarding the demographics, headache symptoms, and associated symptoms. Most OCP users in this study were assumed to have used COC, but information of individual hormone content of OCP was not collected. Patients with nonoral hormonal contraceptives were excluded for further comparison. Results: The use of OCP was common (47.8%) among the study cohort. Compared to those without OCP use ( n = 410), patients with OCP use ( n = 493) were younger (27.4 ± 7.0 vs. 32.8 ± 7.9, p < 0.001), had lower headache frequency (days per month, 11.1 ± 7.5 vs. 12.3 ± 8.8, p = 0.03), were less likely to have osmophobia (47.3 vs. 54.4%, p = 0.033) or cranial autonomic symptoms (44.8 vs. 53.2%, p = 0.013), and more commonly reported menstrually-related worsening of headache (52.3 vs. 42.4%, p = 0.012). The proportion of migraine with aura or other headache characteristics including severity, unilaterality, and pulsatile characteristic showed no differences between groups. Conclusion: Our data provide real-life information about contraceptive use among patients with migraine. The use of OCP is associated with differences in migraine symptomatology. Further studies are needed to determine whether this relationship is causal and any possible underlying mechanism.


2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sameerah Mustafa ◽  
Asal Tawfeeq ◽  
Hadeel Hasan

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.


2020 ◽  
Vol 35 (3) ◽  
Author(s):  
Tayyaba Gul Malik ◽  
Hina Nadeem ◽  
Eiman Ayesha ◽  
Rabail Alam

Objective: To study the effect of short-term use of oral contraceptive pills on intra-ocular pressures of women of childbearing age.   Methods: It was a comparative observational study, conducted at Arif memorial teaching hospital and Allied hospital Faisalabad for a period of six months. Hundred female subjects were divided into two groups of 50 each. Group A, included females, who had been taking oral contraceptive pills (OCP) for more than 6 months and less than 36 months. Group B, included 50 age-matched controls, who had never used OCP. Ophthalmic and systemic history was taken. Careful Slit lamp examination was performed and intraocular pressures (IOP) were measured using Goldman Applanation tonometer. Fundus examination was done to rule out any posterior segment disease. After collection of data, we analyzed and compared the intra ocular pressures between the two groups by using ANOVA in SPSS version 21.   Results: Average duration of using OCP was 14.9 months. There was no significant difference of Cup to Disc ratios between the two groups (p= 0.109). However, significant difference was noted between the IOP of OCP group and controls. (p=0.000). Conclusion: OCP significantly increase IOP even when used for short time period.


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