scholarly journals Oral contraceptive pills are associated with artifacts in ThinPrep Pap smears that mimic low-grade squamous intraepithelial lesions

Cancer ◽  
2002 ◽  
Vol 99 (2) ◽  
pp. 75-82 ◽  
Author(s):  
Carl Morrison ◽  
Patricia Prokorym ◽  
Clara Piquero ◽  
Paul E. Wakely ◽  
Gerard J. Nuovo
2016 ◽  
Vol 7 (2) ◽  
pp. 109-112
Author(s):  
Jayashree Vinay Joshi ◽  
Sujata S. Jagtap ◽  
Prajakta Hemant Paradkar ◽  
Priya Walwatkar ◽  
Hemant S. Paradkar ◽  
...  

1999 ◽  
Vol 123 (9) ◽  
pp. 817-821 ◽  
Author(s):  
Luis A. Díaz-Rosario ◽  
Salim E. Kabawat

Abstract Background.—A patented, fluid-based, thin-layer method for preparation of Papanicolaou (Pap) smears (ThinPrep Pap test) has been reported to be significantly more effective than the conventional smear invented by George Papanicolaou. We tested this position by comparing the cytologic diagnosis and specimen adequacy results obtained using the ThinPrep method with data from conventional Pap smears obtained from a similar population. Methods.—Test results of 56 339 ThinPrep specimens were compared with results from 74 756 conventional smear cases obtained from the same sources in a corresponding period of the previous year. Results.—The use of ThinPrep for cervicovaginal cytology produced a 75.14% increase in the detection of low-grade squamous intraepithelial lesions and higher diagnoses. Detection of low-grade squamous intraepithelial lesions increased by 71.65% (from 1.58% to 2.71%), and detection of high-grade squamous intraepithelial lesions increased by 102.54% (from 0.26% to 0.52%). There was a 39.11% decrease in the atypical squamous cells of undetermined significance–intraepithelial lesion ratio (from 2.07 to 1.26). There were also marked decreases in the number of specimens categorized as “satisfactory but limited,” owing to obscuring inflammation (−94.34%), obscuring blood (−99.84%), and poor fixation (−99.25%). Conclusion.—ThinPrep produced increased detection of premalignant precursors while improving specimen adequacy.


2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sameerah Mustafa ◽  
Asal Tawfeeq ◽  
Hadeel Hasan

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.


2020 ◽  
Vol 35 (3) ◽  
Author(s):  
Tayyaba Gul Malik ◽  
Hina Nadeem ◽  
Eiman Ayesha ◽  
Rabail Alam

Objective: To study the effect of short-term use of oral contraceptive pills on intra-ocular pressures of women of childbearing age.   Methods: It was a comparative observational study, conducted at Arif memorial teaching hospital and Allied hospital Faisalabad for a period of six months. Hundred female subjects were divided into two groups of 50 each. Group A, included females, who had been taking oral contraceptive pills (OCP) for more than 6 months and less than 36 months. Group B, included 50 age-matched controls, who had never used OCP. Ophthalmic and systemic history was taken. Careful Slit lamp examination was performed and intraocular pressures (IOP) were measured using Goldman Applanation tonometer. Fundus examination was done to rule out any posterior segment disease. After collection of data, we analyzed and compared the intra ocular pressures between the two groups by using ANOVA in SPSS version 21.   Results: Average duration of using OCP was 14.9 months. There was no significant difference of Cup to Disc ratios between the two groups (p= 0.109). However, significant difference was noted between the IOP of OCP group and controls. (p=0.000). Conclusion: OCP significantly increase IOP even when used for short time period.


2015 ◽  
Vol 1 ◽  
pp. 101-108 ◽  
Author(s):  
Naomi Jay ◽  
J. Michael Berry ◽  
Christine Miaskowski ◽  
Misha Cohen ◽  
Elizabeth Holly ◽  
...  

1991 ◽  
Vol 29 (7) ◽  
pp. 28-28

We note an important correction to which the CMO, Health Trends and Prescribers Journal have already drawn attention. The first sentence of section 2.3.14 (p 37) should read “If any pill is omitted from the 21 days of active pills, additional contraception (barriers and spermicides) should be used for the 7 days after the pill(s) has been missed”.


2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Samuel Kusheta Katama ◽  
Desalegn Tsegaw Hibstu

Family planning is known not only as a fundamental intervention for improving the health of women but also as a human right. The aim of this study was to assess the current knowledge, attitude and practice of contraceptive use among female students in Dilla secondary and preparatory school, Dilla, South Ethiopia, 2014. A cross sectional study was conducted among 288 female students in Dilla secondary and preparatory school, south Ethiopia, June 19- 29/2014. A simple random sampling technique was used to select the study subjects. The data was collected using a self-administered structured questionnaire. The data was analyzed by SPSS 20. Chi-square test was used to identify associated factors. A total of 263 female students were involved in this study, of which 249 (94.7%) had good knowledge about contraception. The three most frequently identified methods were injectable form (83.9%), oral contraceptive pills (72.7%) and condom (48.6%). A total of 15.7% respondents ever used contraceptive. Among the users, 56.4% used oral contraceptive pills, and 23.1 and 10.2% used injectable form and condom, respectively. In spite of the fact that most respondents had good knowledge of contraception, their attitude and practice was low. Emphasis needs to be given on disseminating health information concerning the attitude and practice of contraceptive method.


Sign in / Sign up

Export Citation Format

Share Document