Comparison of alternative mesenchymal stem cell sources for cell banking and musculoskeletal advanced therapies

2011 ◽  
Vol 112 (5) ◽  
pp. 1418-1430 ◽  
Author(s):  
Carola Cavallo ◽  
Carmela Cuomo ◽  
Sara Fantini ◽  
Francesca Ricci ◽  
Pier Luigi Tazzari ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Advanced Therapies ◽  
Cell Banking ◽  
Cell Sources

scholarly journals Isolation and Characterization of a Human Fetal Mesenchymal Stem Cell Population: Exploring the Potential for Cell Banking in Wound Healing Therapies

2019 ◽  
Vol 28 (11) ◽  
pp. 1404-1419
Author(s):  
Roger Esteban-Vives ◽  
Jenny Ziembicki ◽  
Myung Sun Choi ◽  
R. L. Thompson ◽  
Eva Schmelzer ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Dermal Fibroblasts ◽  
Stem Cell Population ◽  
Differentiation Potential ◽  
Isolation And Characterization ◽  
Cell Banking ◽  
Lineage Stability

Various cell-based therapies are in development to address chronic and acute skin wound healing, for example for burns and trauma patients. An off-the-shelf source of allogeneic dermal cells could be beneficial for innovative therapies accelerating the healing in extensive wounds where the availability of a patient’s own cells is limited. Human fetal-derived dermal fibroblasts (hFDFs) show high in vitro division rates, exhibit low immunological rejection properties, and present scarless wound healing in the fetus, and previous studies on human fetal tissue-derived cell therapies have shown promising results on tissue repair. However, little is known about cell lineage stability and cell differentiation during the cell expansion process, required for any potential therapeutic use. We describe an isolation method, characterize a population, and investigate its potential for cell banking and thus suitability as a potential product for cell grafting therapies. Our results show hFDFs and a bone marrow-derived mesenchymal stem cell (BM-MSC) line shared identification markers and in vitro multilineage differentiation potential into osteogenic, chondrogenic, and adipogenic lineages. The hFDF population exhibited similar cell characteristics as BM-MSCs while producing lower pro-inflammatory cytokine IL-6 levels and higher levels of the wound healing factor hepatocyte growth factor. We demonstrate in vitro differentiation of hFDFs, which may be a problem in maintaining long-term lineage stability, potentially limiting their use for cell banking and therapy development.

Examination of Hydrogels and Mesenchymal Stem Cell Sources for Bioprinting of Artificial Osteogenic Tissues

2019 ◽  
Vol 12 (6) ◽  
pp. 583-597 ◽  
Author(s):  
Maximilian Wehrle ◽  
Fritz Koch ◽  
Stefan Zimmermann ◽  
Peter Koltay ◽  
Roland Zengerle ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Sources

scholarly journals ID3026 Current use and clinical studies of stem cells therapy for osteoarthritis in Viet Nam

2017 ◽  
Vol 4 (S) ◽  
pp. 36
Author(s):  
Tung Dang-Xuan Tran
Keyword(s):  
Rheumatoid Arthritis ◽  
Stem Cells ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Therapy ◽  
Viet Nam ◽  
Medical Problems ◽  
Mesenchymal Stem Cell Therapy ◽  
Advanced Therapies ◽  
Stem Cells Therapy

Mesenchymal Stem Cell Therapy (MSC) is one of the newest and most advanced therapies in Regenerative and Integrative Medicine for a variety of medical problems that are not easily treated with traditional conventional allopathic medical approaches. There is an abundance of clinical experience by numerous physicians, patients and researchers proving consistently that mesenchymal stem cell-MSC therapy can be extremely helpful in Osteoarthritis and Rheumatoid Arthritis. In Viet Nam we have several researches in stem cells clinical application in OA

Comparative osteogenic transcription profiling of various fetal and adult mesenchymal stem cell sources

2008 ◽  
Vol 76 (9) ◽  
pp. 946-957 ◽  
Author(s):  
Pascale V. Guillot ◽  
Cosimo De Bari ◽  
Francesco Dell'Accio ◽  
Hitoshi Kurata ◽  
Julia Polak ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Transcription Profiling ◽  
Cell Sources ◽  
Adult Mesenchymal Stem Cell

COMPARATIVE ESTIMATION OF MESENCHYMAL STEM CELL SOURCES: BONE MARROW AND ADIPOSE TISSUE

2019 ◽  
Vol 10 (9) ◽  
Author(s):  
Constantin Zaitsev ◽  
Igor Khlusov ◽  
Oksana Zhukova ◽  
Alena Gostyukhina ◽  
Natal’ya Abdulkina ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Adipose Tissue ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Sources

Mesenchymal stem cell therapy in treatment of erectile dysfunction: Autologous or allogeneic cell sources?

2014 ◽  
Vol 21 (12) ◽  
pp. 1280-1285 ◽  
Author(s):  
Naside Mangir ◽  
Cem Akbal ◽  
Tufan Tarcan ◽  
Ferruh Simsek ◽  
Levent Turkeri
Keyword(s):  
Stem Cell ◽  
Erectile Dysfunction ◽  
Mesenchymal Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Mesenchymal Stem Cell Therapy ◽  
Allogeneic Cell ◽  
Cell Sources
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