Haptide-coated collagen sponge as a bioactive matrix for tissue regeneration

2008 ◽  
Vol 84B (2) ◽  
pp. 571-583 ◽  
Author(s):  
Gerard Marx ◽  
Anna Hotovely-Salomon ◽  
Lila Levdansky ◽  
Elena Gaberman ◽  
Ganit Snir ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Collagen Sponge ◽  
Coated Collagen

scholarly journals “Birdlime” technique using TachoSil tissue sealing sheet soaked with fibrin glue for sutureless vessel transposition in microvascular decompression: operative technique and nuances

2018 ◽  
Vol 128 (5) ◽  
pp. 1522-1529 ◽  
Author(s):  
Naoki Otani ◽  
Terushige Toyooka ◽  
Kazuya Fujii ◽  
Kosuke Kumagai ◽  
Satoru Takeuchi ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Microvascular Decompression ◽  
Cranial Nerves ◽  
Collagen Sponge ◽  
Radiographic Findings ◽  
Tissue Glue ◽  
Cerebellar Artery ◽  
Offending Artery ◽  
Coated Collagen ◽  
Tissue Sealing

OBJECTIVEMicrovascular decompression (MVD) is effective for the treatment of trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia. The transposition technique is the standard procedure to avoid adhesions and granuloma around the decompression site but is more complex and difficult to perform than the interposition technique. The authors describe a simple and safe MVD transposition procedure they call the “birdlime” technique, which uses a tissue glue–coated collagen sponge soaked with fibrin glue, and the results of this technique.METHODSThe authors retrospectively reviewed the medical charts and radiographic findings of 27 consecutive patients with TN (8 patients) and HFS (19 patients) who, between January 2012 and December 2015, had undergone an MVD transposition procedure utilizing a tissue glue–coated collagen sponge (TachoSil tissue sealing sheet) soaked with fibrin glue (Tisseel 2-component fibrin sealant, vapor heated). Offending arteries among the patients with TN were the superior cerebellar artery (SCA) in 5 patients, the SCA and anterior inferior cerebellar artery (AICA) in 2, and the AICA in 1. Those among the patients with HFS were the vertebral artery (VA) in 3 patients, the VA and AICA in 4, the VA and posterior inferior cerebellar artery (PICA) in 3, the PICA in 4, the AICA in 1, the AICA-PICA in 3, and the PICA and AICA in 1. Operations were performed according to the Jannetta procedure. The offending artery was transposed and fixed to the dura mater of the petrous bone using TachoSil pieces soaked with fibrin glue. Postoperative constructive interference in steady-state MRI was performed to evaluate the change in the position of the offending artery.RESULTSTransposition of the offending artery was easily and safely performed in all patients. All patients had total remission of symptoms directly after the procedure. No severe complications occurred. The postoperative course was uneventful. No recurrences, adhesions, or dysfunction of the cranial nerves was observed in any of the patients. Postoperative MRI showed that the offending vessels were displaced and fixed in the appropriate position.CONCLUSIONSThe described transposition technique provides an easy and adjustable way to perform MVD safely and effectively. In addition, this transposition and fixation technique is simple and avoids the risk of needle injury close to the cranial nerves and vessels. This simple sutureless technique is recommended for MVD to reduce the risk of intraoperative neurovascular injury.

Cartilage tissue regeneration from bone marrow cells by RWV bioreactor using collagen sponge scaffold

2009 ◽  
Vol 29 (4) ◽  
pp. 1150-1155 ◽  
Author(s):  
Yoshimi Ohyabu ◽  
Junzo Tanaka ◽  
Yoshito Ikada ◽  
Toshimasa Uemura
Keyword(s):  
Bone Marrow ◽  
Tissue Regeneration ◽  
Bone Marrow Cells ◽  
Collagen Sponge ◽  
Cartilage Tissue ◽  
Marrow Cells

scholarly journals A Comparison of Conventional Collagen Sponge and Collagen-Gelatin Sponge in Wound Healing

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Chizuru Jinno ◽  
Naoki Morimoto ◽  
Ran Ito ◽  
Michiharu Sakamoto ◽  
Shuichi Ogino ◽  
...  
Keyword(s):  
Wound Healing ◽  
Tissue Regeneration ◽  
Saline Solution ◽  
Collagen Sponge ◽  
Gelatin Sponge ◽  
Fibroblast Growth ◽  
Wound Area ◽  
Thickness Skin ◽  
Tissue Area ◽  
Tissue Specimens

The objective of this study was to compare the effectiveness of the collagen-gelatin sponge (CGS) with that of the collagen sponge (CS) in dermis-like tissue regeneration. CGS, which achieves the sustained release of basic fibroblast growth factor (bFGF), is a promising material in wound healing. In the present study, we evaluated and compared CGSs and conventional CSs. We prepared 8 mm full-thickness skin defects on the backs of rats. Either CGSs or CSs were impregnated with normal saline solution (NSS) or 7 μg/cm2of bFGF solution and implanted into the defects. At 1 and 2 weeks after implantation, tissue specimens were obtained from the rats of each group (n=3, totaln=24). The wound area, neoepithelial length, dermis-like tissue area, and the number and area of capillaries were evaluated at 1 and 2 weeks after implantation. There were no significant differences in the CGS without bFGF and CS groups. Significant improvements were observed in the neoepithelial length, the dermis-like tissue area, and the number of newly formed capillaries in the group of rats that received CGSs impregnated with bFGF. The effects on epithelialization, granulation, and vascularization of wound healing demonstrated that, as a scaffold, CGSs are equal or superior to conventional CSs.

Periodontal Tissue Regeneration Using Brain-Derived Neurotrophic Factor Delivered by Collagen Sponge

2019 ◽  
Vol 25 (15-16) ◽  
pp. 1072-1083 ◽  
Author(s):  
Ilana Ramalho ◽  
Edmara Bergamo ◽  
Adolfo Lopes ◽  
Camille Medina-Cintrón ◽  
Rodrigo Neiva ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Collagen Sponge ◽  
Periodontal Tissue ◽  
Periodontal Tissue Regeneration

Apatite-Coated Collagen Sponge for the Delivery of Bone Morphogenetic Protein-2 in Rabbit Posterolateral Lumbar Fusion

2014 ◽  
Vol 38 (10) ◽  
pp. 893-899 ◽  
Author(s):  
Ki Hyoung Koo ◽  
Jung Min Ahn ◽  
Jong Min Lee ◽  
Byung-Soo Kim ◽  
Chang-Sung Kim ◽  
...  
Keyword(s):  
Bone Morphogenetic Protein ◽  
Lumbar Fusion ◽  
Collagen Sponge ◽  
Bone Morphogenetic Protein 2 ◽  
Posterolateral Lumbar Fusion ◽  
Morphogenetic Protein ◽  
Coated Collagen

Decellularized bone extracellular matrix in skeletal tissue engineering

2020 ◽  
Vol 48 (3) ◽  
pp. 755-764
Author(s):  
Benjamin B. Rothrauff ◽  
Rocky S. Tuan
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Tissue Regeneration ◽  
Animal Studies ◽  
Tumor Resection ◽  
Regenerative Capacity ◽  
Skeletal Tissue ◽  
Large Bone

Bone possesses an intrinsic regenerative capacity, which can be compromised by aging, disease, trauma, and iatrogenesis (e.g. tumor resection, pharmacological). At present, autografts and allografts are the principal biological treatments available to replace large bone segments, but both entail several limitations that reduce wider use and consistent success. The use of decellularized extracellular matrices (ECM), often derived from xenogeneic sources, has been shown to favorably influence the immune response to injury and promote site-appropriate tissue regeneration. Decellularized bone ECM (dbECM), utilized in several forms — whole organ, particles, hydrogels — has shown promise in both in vitro and in vivo animal studies to promote osteogenic differentiation of stem/progenitor cells and enhance bone regeneration. However, dbECM has yet to be investigated in clinical studies, which are needed to determine the relative efficacy of this emerging biomaterial as compared with established treatments. This mini-review highlights the recent exploration of dbECM as a biomaterial for skeletal tissue engineering and considers modifications on its future use to more consistently promote bone regeneration.

192: Tubularized Urethral Replacement: What is the Maximum Distance for Normal Tissue Regeneration?

2004 ◽  
Vol 171 (4S) ◽  
pp. 51-51
Author(s):  
Roger E. De Filippo ◽  
Hans G. Pohl ◽  
James J. Yoo ◽  
Anthony Atala
Keyword(s):  
Tissue Regeneration ◽  
Normal Tissue ◽  
Maximum Distance
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