Antibacterial activity of nitric oxide‐releasing carboxymethylcellulose against periodontal pathogens

2020 ◽  
Author(s):  
Evan S. Feura ◽  
Lei Yang ◽  
Mark H. Schoenfisch
Keyword(s):  
Nitric Oxide ◽  
Antibacterial Activity ◽  
Periodontal Pathogens ◽  
Nitric Oxide Releasing

scholarly journals Antibacterial Activity of Nitric Oxide-Releasing Hyperbranched Polyamidoamines

2017 ◽  
Vol 29 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Lei Yang ◽  
Xingzhi Wang ◽  
Dakota J. Suchyta ◽  
Mark H. Schoenfisch
Keyword(s):  
Nitric Oxide ◽  
Antibacterial Activity ◽  
Nitric Oxide Releasing

scholarly journals Antibacterial activity of nitric oxide releasing silver nanoparticles

2017 ◽  
Vol 838 ◽  
pp. 012031 ◽  
Author(s):  
Amedea B. Seabra ◽  
Nixson Manosalva ◽  
Bruna de Araujo Lima ◽  
Milena T. Pelegrino ◽  
Marcelo Brocchi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Nitric Oxide Releasing

scholarly journals Nitric Oxide-Releasing Thermoresponsive Pluronic F127/Alginate Hydrogel for Enhanced Antibacterial Activity and Accelerated Healing of Infected Wounds

Pharmaceutics ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 926
Author(s):  
Jiafu Cao ◽  
Mingzhi Su ◽  
Nurhasni Hasan ◽  
Juho Lee ◽  
Dongmin Kwak ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Wound Healing ◽  
Antibacterial Activity ◽  
Multidrug Resistant ◽  
Pluronic F127 ◽  
Scanning Calorimetry ◽  
No Release ◽  
Infected Wounds ◽  
Nitric Oxide Releasing

Nitric oxide (NO), a highly reactive and lipophilic molecule, is one of the molecules present in the wound environment and implicated as an important regulator in all phases of wound healing. Here, we developed an NO-releasing thermoresponsive hydrogel (GSNO-PL/AL) composed of S-nitrosoglutathione (GSNO), pluronic F127 (PL), and alginate (AL) for the treatment of infected wounds. The GSNO was incorporated into the thermoresponsive PL/AL hydrogel, and differential scanning calorimetry techniques were used for the hydrogel characterization. The hydrogel was assessed by in vitro NO release, antibacterial activity, cytotoxicity, and wound-healing activity. The GSNO-PL/AL hydrogel demonstrated thermal responsiveness and biocompatibility, and it showed sustained NO release for 7 days. It also exhibited potent bactericidal activity against Gram-positive methicillin-resistant Staphylococcus aureus and Gram-negative multidrug-resistant Pseudomonas aeruginosa (MRPA). Moreover, the GSNO-PL/AL treatment of MRPA-infected wounds accelerated healing with a reduced bacterial burden in the wounds. The GSNO-PL/AL hydrogel would be a promising option for the treatment of infected wounds.

Evaluation of antibacterial activity of nitric oxide-releasing polymeric particles against Staphylococcus aureus and Escherichia coli from bovine mastitis

2014 ◽  
Vol 473 (1-2) ◽  
pp. 20-29 ◽  
Author(s):  
Viviane F. Cardozo ◽  
Cesar A.C. Lancheros ◽  
Adélia M. Narciso ◽  
Elaine C.S. Valereto ◽  
Renata K.T. Kobayashi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bovine Mastitis ◽  
Polymeric Particles ◽  
Nitric Oxide Releasing

Nitric Oxide-Releasing Biomaterials for Biomedical Applications

2016 ◽  
Vol 23 (24) ◽  
pp. 2579-2601 ◽  
Author(s):  
Xin Zhou ◽  
Jimin Zhang ◽  
Guowei Feng ◽  
Jie Shen ◽  
Deling Kong ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Biomedical Applications ◽  
Nitric Oxide Releasing
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