scholarly journals In vitro evaluation of 3D bioprinted tri-polymer network scaffolds for bone tissue regeneration

2017 ◽  
Vol 105 (12) ◽  
pp. 3262-3272 ◽  
Author(s):  
Stephanie T. Bendtsen ◽  
Mei Wei
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Polymer Network ◽  
Bone Tissue Regeneration ◽  
In Vitro Evaluation

In vitro evaluation of simvastatin acid (SVA) coated beta-tricalcium phosphate (β-TCP) particle on bone tissue regeneration

2012 ◽  
Vol 20 (7) ◽  
pp. 754-761
Author(s):  
Dae Hyeok Yang ◽  
Min Soo Bae ◽  
Lingjuan Qiao ◽  
Dong Nyoung Heo ◽  
Jung Bok Lee ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Tricalcium Phosphate ◽  
Bone Tissue Regeneration ◽  
In Vitro Evaluation ◽  
Beta Tricalcium Phosphate ◽  
Simvastatin Acid

scholarly journals Synthesis of hybrid materials based polyester urethanes/ TiO2 and in vitro evaluation as potential biomaterial for bone tissue regeneration

2016 ◽  
Vol 4 ◽  
Author(s):  
Rodr�guez-Lorenzo Luis ◽  
Gonz�lez �Garc�a Dulce ◽  
Jim�nez-Gallegos Rodrigo ◽  
T�llez- Jurado Lucia ◽  
Mart�nez-Morales. Carmen
Keyword(s):  
Bone Tissue ◽  
Hybrid Materials ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
In Vitro Evaluation

scholarly journals Fabrication of High-Strength and Porous Hybrid Scaffolds Based on Nano-Hydroxyapatite and Human-Like Collagen for Bone Tissue Regeneration

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 61 ◽  
Author(s):  
Yannan Liu ◽  
Juan Gu ◽  
Daidi Fan
Keyword(s):  
Mechanical Properties ◽  
Enzymatic Hydrolysis ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Repair ◽  
Three Dimensional ◽  
High Strength ◽  
Biological Properties ◽  
Bone Tissue Regeneration

A novel, three-dimensional, porous, human-like collagen (HLC)/nano-hydroxyapatite (n-HA) scaffold cross-linked by 1,2,7,8-diepoxyoctane (DEO) was successfully fabricated, which showed excellent mechanical and superior biological properties for bone tissue regeneration in this study. The physicochemical characterizations of different n-HA/HLC/DEO (nHD) scaffolds were investigated by determining the morphology, compression stress, elastic modulus, Young’s modulus and enzymatic hydrolysis behavior in vitro. The results demonstrated that nHD-2 and nHD-3 scaffolds showed superior mechanical properties and resistance to enzymatic hydrolysis compared to nHD-1 scaffolds. The cell viability, live cell staining and cell adhesion analysis results demonstrated that nHD-2 scaffolds exhibited low cytotoxicity and excellent cytocompatibility compared with nHD-1 and nHD-3 scaffolds. Furthermore, subcutaneous injections of nHD-2 scaffolds in rabbits produced superior anti-biodegradation effects and histocompatibility compared with injections of nHD-1 and nHD-3 scaffolds after 1, 2 and 4 weeks. In addition, the repair of bone defects in rabbits demonstrated that nHD-2 scaffolds presented an improved ability for guided bone regeneration and reconstruction compared to commercially available bone scaffold composite hydroxyapatite/collagen (HC). Collectively, the results show that nHD-2 scaffolds show promise for application in bone tissue engineering due to their excellent mechanical properties, anti-biodegradation, anti-biodegradation, biocompatibility and bone repair effects.

Enhancing in vitro bioactivity and in vivo osteogenesis of organic–inorganic nanofibrous biocomposites with novel bioceramics

2014 ◽  
Vol 2 (37) ◽  
pp. 6293-6305 ◽  
Author(s):  
Tao Liu ◽  
Xinbo Ding ◽  
Dongzhi Lai ◽  
Yongwei Chen ◽  
Ridong Zhang ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Biological Properties ◽  
Bone Tissue Regeneration ◽  
In Vitro Bioactivity ◽  
Physicochemical And Biological Properties

MGHA-introduced, an electrospun SF-based composite can exhibit improved physicochemical and biological properties to stimulate bone tissue regeneration and repair.

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