scholarly journals High metabolic rate and stem cell characteristics of esophageal cancer stem‐like cells depend on the Hsp27–AKT–HK2 pathway

2019 ◽  
Vol 145 (8) ◽  
pp. 2144-2156 ◽  
Author(s):  
Chen‐Chi Liu ◽  
Kun‐Ta Chou ◽  
Jyuan‐Wei Hsu ◽  
Jiun‐Han Lin ◽  
Tien‐Wei Hsu ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Stem Cell ◽  
Metabolic Rate ◽  
High Metabolic Rate

Viral Susceptibility and Embryonic Differentiation.

Development ◽  
1963 ◽  
Vol 11 (4) ◽  
pp. 757-764
Author(s):  
Juhani Rapola ◽  
Tapani Vainio ◽  
Lauri Saxén
Keyword(s):  
Tissue Culture ◽  
Viral Replication ◽  
Metabolic Rate ◽  
Tissue Damage ◽  
Embryonic Tissue ◽  
High Metabolic Rate ◽  
Viral Susceptibility ◽  
Proliferative Rate ◽  
Active Proliferation ◽  
Severe Tissue

The fact that viral susceptibility changes during embryogenesis has been pointed out by both experimental embryologists and clinical practitioners, not to mention virologists working with avian material. In attempts to find the fundamental factors which make embryonic tissue susceptible or resistant to a given virus, the metabolic and proliferative rate have been considered relevant (Williamson et al., 1953; Robertson et al., 1955; Töndury, 1956). Experience accumulated in studies of the replication of various viruses in tissue culture has taught us that a high metabolic rate and active proliferation may not always enhance viral replication (Ginsberg, 1958). However, there seems to be justification for the view that an injurious agent leads to more severe tissue damage when it exercises its effect upon actively proliferating tissues than when it does so at the ‘resting stage’.

The metabolic rate and thermal conductance of the eastern barred bandicoot (Perameles gunnii) at different ambient temperatures

2003 ◽  
Vol 51 (6) ◽  
pp. 603 ◽  
Author(s):  
M. P. Ikonomopoulou ◽  
R. W. Rose
Keyword(s):  
Oxygen Consumption ◽  
Body Temperature ◽  
Metabolic Rate ◽  
Thermal Conductance ◽  
The Body ◽  
High Metabolic Rate ◽  
Ambient Temperatures ◽  
Reduced Body ◽  
Thermoneutral Zone ◽  
Reproductive Females

We investigated the metabolic rate, thermoneutral zone and thermal conductance of the eastern barred bandicoot in Tasmania. Five adult eastern barred bandicoots (two males, three non-reproductive females) were tested at temperatures of 3, 10, 15, 20, 25, 30, 35 and 40°C. The thermoneutral zone was calculated from oxygen consumption and body temperature, measured during the daytime: their normal resting phase. It was found that the thermoneutral zone lies between 25°C and 30°C, with a minimum metabolic rate of 0.51 mL g–1 h–1 and body temperature of 35.8°C. At cooler ambient temperatures (3–20°C) the body temperature decreased to approximately 34.0°C while the metabolic rate increased from 0.7 to 1.3 mL g–1�h–1. At high temperatures (35°C and 40°C) both body temperature (36.9–38.7°C) and metabolic rate (1.0–1.5 mL g–1 h–1) rose. Thermal conductance was low below an ambient temperature of 30°C but increased significantly at higher temperatures. The low thermal conductance (due, in part, to good insulation, a reduced body temperature at lower ambient temperatures, combined with a relatively high metabolic rate) suggests that this species is well adapted to cooler environments but it could not thermoregulate easily at temperatures above 30°C.

scholarly journals Prediction of response to radiotherapy in the treatment of esophageal cancer using stem cell markers

2013 ◽  
Vol 107 (3) ◽  
pp. 434-441 ◽  
Author(s):  
Justin K. Smit ◽  
Hette Faber ◽  
Maarten Niemantsverdriet ◽  
Mirjam Baanstra ◽  
Johan Bussink ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Stem Cell ◽  
Stem Cell Markers ◽  
Prediction Of Response ◽  
Cell Markers

scholarly journals On the metabolic gradient of the frog's egg

1923 ◽  
Vol 94 (660) ◽  
pp. 232-249 ◽  
Keyword(s):  
Cell Division ◽  
Metabolic Rate ◽  
Experimental Work ◽  
Electric Potential ◽  
High Rate ◽  
High Metabolic Rate ◽  
Remarkable Degree ◽  
Toxic Agents ◽  
The Individual ◽  
Low Rate

After a very considerable amount of work, chiefly on regeneration of certain hydroids and flatworms, Child came to the conclusion that in the adult forms there is a gradient in the rate of metabolism extending from a region of high rate at the anterior end to a region of low rate at the posterior end. On this basis he was able to predict with a remarkable degree of success many results which might be obtained in experimental work on regeneration in these forms. As a further result he enunciated his “Dynamic Conception of the Individual.” In this conception he postulates that in all organisms there is a gradient in the rate of metabolism from a dominant region of high metabolic rate to regions of a lower rate. In axiate organisms this dominant region is at the anterior or apical end, and the rate of metabolism decreases towards the posterior or basal end. These gradients are evidenced in a variety of ways. There may be an apico-basal gradient in the rate of cell division in a cleaving egg or in the rate of morphogenesis, the organs of the apical end developing before those of the basal end. There is often a gradient in the ease with which intra vitam stains will stain the various regions of the organism. There may be a gradient in electric potential, or in the susceptibility of the organism to toxic agents.

scholarly journals Tu1699 Autophagy Regulates Esophageal Cancer Stem Cell Phenotypic Plasticity by Targeting Mitochondria and Oxidative Stress

2014 ◽  
Vol 146 (5) ◽  
pp. S-821
Author(s):  
Kelly A. Whelan ◽  
Shingo Kagawa ◽  
Andy Guo ◽  
Mitsuteru Natsuizaka ◽  
Hideaki Kinugasa ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Esophageal Cancer ◽  
Stem Cell ◽  
Phenotypic Plasticity ◽  
Cancer Stem Cell ◽  
And Oxidative Stress

The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells

2010 ◽  
Vol 24 (4) ◽  
pp. 265-273 ◽  
Author(s):  
S.-M. Che ◽  
X.-Z. Zhang ◽  
X.-L. Liu ◽  
X. Chen ◽  
L. Hou
Keyword(s):  
Esophageal Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell
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