About the Name Yoruba

A curious debate is going on about the group name of the Yoruba nation, the name ‘Yoruba’. All sorts of strange and fanciful things are being said about this name. Also, many people are calling on me to intervene in the debate. I therefore hereby intervene. But I cannot participate in the more flippant levels of debate over this or any matter; I can only make known the results of my serious research. I might add that what I reveal here is a small peep into a very important body of research on the Yoruba nation, a body of research that will, hopefully, soon appear as a book on the profile of the Yoruba nation. In modern times, the Yorùba people in Nigeria have exhibited a remarkable ́ degree and quality of unity as a people. Such strong unity is engendered primarily by their common love of, and pride in, their culture, their strong emphasis on development and modernization, and in their civilizational achievements in history and in modern times. It is also reinforced by their common identity with such ideals as love of freedom, respect for the individual, accountability of leadership and governance, the servanthood of rulers, religious tolerance and accommodation, hospitality towards all other peoples, tenacity in fighting for ideals, and a unique fixation, as a people, on progress in all facets of modern development and transformation.

Précis of Talking to Our Selves

One of the most unsettling lessons from recent psychological research is that people are routinely mistaken about the origins of their behavior. Yet philosophical orthodoxy holds that the exercise of morally responsible agency typically requires accurate self-awareness. If the orthodoxy is right, and the psychology is to be believed, people characteristically fail to meet the standards of morally responsible agency, and we are faced with the possibility of skepticism about agency. This chapter is derived from Doris’s Talking to Our Selves (2015b), which responds to the skeptical threat by developing an “anti-refectivist” dialogic theory, where the exercise of morally responsible agency emerges through a collaborative conversational process by which human beings, although afflicted with a remarkable degree of self-ignorance, are able to realize their values in their lives.

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

Despite the involvement of Poly(ADP-ribose) polymerase-1 (PARP1) in many important biological pathways, the target residues of PARP1-mediated ADP-ribosylation remain ambiguous. To explicate the ADP-ribosylation regulome, we analyze human cells depleted for key regulators of PARP1 activity, histone PARylation factor 1 (HPF1) and ADP-ribosylhydrolase 3 (ARH3). Using quantitative proteomics, we characterize 1,596 ADP-ribosylation sites, displaying up to 1000-fold regulation across the investigated knockout cells. We find that HPF1 and ARH3 inversely and homogenously regulate the serine ADP-ribosylome on a proteome-wide scale with consistent adherence to lysine-serine-motifs, suggesting that targeting is independent of HPF1 and ARH3. Notably, we do not detect an HPF1-dependent target residue switch from serine to glutamate/aspartate under the investigated conditions. Our data support the notion that serine ADP-ribosylation mainly exists as mono-ADP-ribosylation in cells, and reveal a remarkable degree of histone co-modification with serine ADP-ribosylation and other post-translational modifications.

Rotational Ground-State Bands of ¹⁶⁸Hf Nucleus

This paper has been explained to study the rotational arrangement of even-even 168Hf isotope using the phenomenological fitting, Sood’s semi-empirical formula. The rotational energies from the calculated values were compared to the experimental data. The result shows that in 168Hf, calculated energies fit the experimental values to a remarkable degree of accuracy.

L’“uno” e l’“intelletto” dell’anima umana: ricezioni neoplatoniche del Fedro di Platone

Thanks to the exegesis, Iamblichus succeeds in forging a psycho-epistemological doctrine which can boast a remarkable degree of consistency, albeit not always without minor flaws. Notably, the exegesis of Plato’s Phaedrus plays a pivotal role in constructing this system, despite moving not from phrases of the dialogue, but simply from single words, like κυβερνήτης and ἡνίοχος. Iamblichus’ anathema against Plotinus’ psychology makes Socrates’ palinode the sacred text from which to elicit those formulae of orthodoxy bound to be devoutly recited by posterior Platonists, like Hermias of Alexandria. Indeed, in this text the divine Plato has revealed the essence of the triad νοερόν, νοητόν, κριτήριον, whose each element is susceptible of being dichotomized: νοερόν in νοῦς and ἕν, νοητόν in νοητόν and ἀκρότατα νοητά, κριτήριον in καθαρμός/φιλοσοφία and ἐνθουσιασμός/θεουργία. The result of this complex and fascinating move is an outstanding proof of philology and philosophy, psychology and epistemology hermeneutics and mysticism.

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

SUMMARYDespite the involvement of Poly(ADP-ribose) polymerase-1 (PARP1) in many important biological pathways, the target residues of PARP1-mediated ADP-ribosylation remain ambiguous. To explicate the ADP-ribosylation regulome, we analyzed human cells depleted for key regulators of PARP1 activity, histone PARylation factor 1 (HPF1) and ADP-ribosylhydrolase 3 (ARH3). Using quantitative proteomics, we quantified 1,596 ADPr sites, displaying a thousand-fold regulation across investigated knockout cells. We find that HPF1 and ARH3 inversely and homogenously regulate the serine ADP-ribosylome on a proteome-wide scale with consistent adherence to lysine-serine (KS)-motifs suggesting targeting is independent of HPF1 and ARH3. Our data reveal that ADPr globally exists as mono-ADP-ribosylation, and we detail a remarkable degree of histone co-modification with ADPr and other post-translational modifications. Strikingly, no HPF1-dependent target residue switch from serine to glutamate/aspartate was detectable in cells, which challenges current dogma related to PARP1 target residues. Collectively, we elucidate hitherto unappreciated processes related to cellular PARP1 activity.

Recognising Secularisation: The Church of England and Its Struggle for a Political Role (1960–90)

For leaders of the Church of England, secularisation was such an obvious fact that it virtually became a self-fulfilling prophecy as it informed political and theological debates within the Church. This article shows how by adjusting to secularisation the Church demonstrated a remarkable degree of resilience and managed to remain an important national voice – at least until the end of the Thatcher era. Three factors were of particular relevance in this development: First, the use of old networks which gave the Church of England privileged access to the political establishment. Second, the professionalisation of its political structure that equipped the Church with expertise. Third, complex changes within the Anglican theological strands that were opened up for political and social issues. These elements enabled the Church to develop new political agendas that were able to substitute political and moral positions that had become obsolete in the era of secularisation.

Taxonomy and phylogeny of cercosporoid ascomycetes on Diospyros spp. with special emphasis on Pseudocercospora spp.

A worldwide survey of cercosporoid ascomycete species on hosts of the genus Diospyros (persimmon) with key to the species based on characters in vivo is provided. Special emphasis is placed on species of the genus Pseudocercospora, which are in part also phylogenetically analysed, using a multilocus approach. Species of the latter genus proved to be very diverse, with a remarkable degree of cryptic speciation. Seven new species are described (Pseudocercospora diospyri-japonicae, P. diospyriphila, P. ershadii, P. kakiicola, P. kobayashiana, and P. tesselata), and two new names are introduced [P. kakiigena (≡ Cylindrosporium kaki, non Pseudocercospora kaki), and Zasmidium diospyri-hispidae (≡ Passalora diospyri, non Zasmidium diospyri)]. Six taxa are lectotypified (Cercospora atra, C. diospyri, C. diospyri var. ferruginea, C. flexuosa, C. fuliginosa, C. kaki), and Pseudocercospora kaki is epitypified.

Sources and steps of corpus lemmatization

This article describes the steps and results of the lemmatization of the derived anomalous verbs of Old English. The data have been retrieved from The Dictionary of Old English Web Corpus, searched through the lexical database from the Nerthus Project called Norna. The methodology comprises several steps combining automatic searches on the lemmatizer and manual revision. Part of the results, including the verbs starting with the letters A to H, are compared with the Dictionary of Old English, while the rest of the lemmas are checked with the standard Old English dictionaries (Clark-Hall, Sweet and Bosworth-Toller). The discussion leads to the conclusion that the lemmatization of the verbs of Old English, a language with a remarkable degree of spelling variation, requires considerable manual revision. However, the progressive improvement of automatic searches, based on the comparison of the initial results with the available lexicographical sources, minimizes the need for manual adjustment.

Parallel and serial processes in number-to-quantity conversion

Converting a multi-digit number to quantity requires processing not only the digits but also the number’s decimal structure, thus raising several issues. First, are all the digits processed in parallel, or serially from left to right? Second, given that the same digit, at different places, can represent different quantities (e.g., “2” can mean 2, 20, etc.), how is each digit assigned to its correct decimal role? We presented participants with two-digit numbers and asked them to point at the corresponding locations on a number line, while we recorded their pointing trajectory. Crucially, on some trials, the decade and unit digits did not appear simultaneously. When the decade digit was delayed, the decade effect on finger movement was delayed by the same amount. However, a lag in presenting the unit digit delayed the unit effect by 35 ms less than the lag duration, a pattern reminiscent of the psychological refractory period, indicating an idle time window of 35 ms in the units processing pathway. When a lag transiently caused a display of just one digit on screen, the unit effect increased and the decade effect decreased, suggesting errors in binding digits to decimal roles. We propose that a serial bottleneck is imposed by the creation of a syntactic frame for the multidigit number, a process launched by the leftmost digit. All other stages, including the binding of digits to decimal roles, quantification, and merging them into a whole-number quantity, appear to operate in parallel across digits, suggesting a remarkable degree of parallelism in expert readers.