scholarly journals Cigarette smoking, alcohol consumption and subsequent gastric cancer risk by subsite and histologic type

2002 ◽  
Vol 101 (6) ◽  
pp. 560-566 ◽  
Author(s):  
Shizuka Sasazuki ◽  
Satoshi Sasaki ◽  
Shoichiro Tsugane ◽  
Keyword(s):  
Gastric Cancer ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Cigarette Smoking ◽  
Histologic Type ◽  
Gastric Cancer Risk

GlutathioneS-transferase M1, T1 and P1 genetic polymorphisms, cigarette smoking and gastric cancer risk

2005 ◽  
Vol 23 (4) ◽  
pp. 267-272 ◽  
Author(s):  
Lülüfer Tamer ◽  
Nurcan Aras Ateş ◽  
Cengiz Ateş ◽  
Bahadır Ercan ◽  
Tufan Elipek ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Risk ◽  
Cigarette Smoking ◽  
Genetic Polymorphisms ◽  
Gastric Cancer Risk

scholarly journals -765 G>C POLYMORPHISM OF THE COX-2 GENE AND GASTRIC CANCER RISK IN BRAZILIAN POPULATION

2014 ◽  
Vol 51 (2) ◽  
pp. 79-83 ◽  
Author(s):  
Vanessa Maria de Lima Pazine CAMPANHOLO ◽  
Aledson Vitor FELIPE ◽  
Jacqueline Miranda de LIMA ◽  
Célia Aparecida Marques PIMENTA ◽  
Rogéria Maria VENTURA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Smoking Behavior ◽  
Personal Data ◽  
Control Group ◽  
Gastric Cancer Risk ◽  
Increased Risk ◽  
Cox 2 ◽  
Gastric Cancer Patients

ContextGenomic alterations play important roles in gastric cancer carcinogenesis. Cyclooxygenases (COX) are important enzymes in the maintenance of mucosal integrity and in pathological processes, mainly in inflammation and cancer. The -765G>C COX-2 polymorphism has been implicated in gastric cancer risk.ObjectivesTo evaluate the COX-2 gene polymorphism as a predictor of gastric cancer risk.MethodsOne hundred gastric cancer patients and 150 controls were enrolled from a Brazilian centre. Personal data regarding related risk factors, including alcohol consumption and smoking behavior, were collected via questionnaire. DNA was extracted from peripheral blood and the genotypes were analyzed using PCR-restriction fragment length polymorphism.ResultsG/G, G/C and C/C genotypes frequencies was 42.7%, 50% and 7.3%, respectively in controls and 59.0%, 34.0% and 7.0% in gastric cancer. The frequency of the genotypes differed between the groups (P = 0.033). A higher risk of gastric cancer was associated with COX-2 -765G/G genotype (P = 0.048; OR:1.98, 95% CI = 1.01-3.90). Alcohol consumption and smoking in patients with -765G/G genotype also increased the risk of gastric cancer.ConclusionsThe -765G/G genotype and the -765G allele had been associated with an increased risk for gastric cancer. The presence of smoking and alcohol consumption increased the risk for gastric cancer in subjects with -765G/G genotype compared with the control group. Polymorphism of COX-2 gene and gastric cancer risk.

scholarly journals Alcohol consumption and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

2011 ◽  
Vol 94 (5) ◽  
pp. 1266-1275 ◽  
Author(s):  
Eric J Duell ◽  
Noémie Travier ◽  
Leila Lujan-Barroso ◽  
Françoise Clavel-Chapelon ◽  
Marie-Christine Boutron-Ruault ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Gastric Cancer Risk ◽  
Prospective Investigation

scholarly journals Alcohol consumption and gastric cancer risk in Korea: a case-control study

2019 ◽  
Vol 13 (5) ◽  
pp. 425 ◽  
Author(s):  
Mi Hui Kim ◽  
Shin Ah Kim ◽  
Chan Hyuk Park ◽  
Chang Soo Eun ◽  
Dong Soo Han ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Gastric Cancer Risk ◽  
Control Study
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