Enantioselective Synthesis ofβ-Blockersvia Hydrolytic Kinetic Resolution of Terminal Oxiranes by Using Bimetallic Chiral {{2,2′-[Cyclohexane-1,2-diylbis(nitrilomethylidyne)]bis[phenolato]}(2−)}cobalt ([Co(salen)])-Type Complexes

Rahul B. Kawthekar; Geon-Joong Kim

doi:10.1002/hlca.200890037

Enantioselective Synthesis ofβ-Blockersvia Hydrolytic Kinetic Resolution of Terminal Oxiranes by Using Bimetallic Chiral {{2,2′-[Cyclohexane-1,2-diylbis(nitrilomethylidyne)]bis[phenolato]}(2−)}cobalt ([Co(salen)])-Type Complexes

Helvetica Chimica Acta ◽

10.1002/hlca.200890037 ◽

2008 ◽

Vol 91 (2) ◽

pp. 317-332 ◽

Cited By ~ 27

Author(s):

Rahul B. Kawthekar ◽

Geon-Joong Kim

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution

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ChemInform Abstract: Enantioselective Synthesis of β-Blockers via Hydrolytic Kinetic Resolution of Terminal Oxiranes by Using Bimetallic Chiral {{2,2′-[Cyclohexane-1,2-diylbis(nitrilomethylidyne)]bis [phenolato]}(2-)}cobalt ([Co(salen)])-Type Complexes.

ChemInform ◽

10.1002/chin.200825111 ◽

2008 ◽

Vol 39 (25) ◽

Author(s):

Rahul B. Kawthekar ◽

Geon-Joong Kim

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution ◽

Β Blockers

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A concise enantioselective synthesis of 1,4-dideoxy-1,4-imino-d-arabinitol using Co(III)(salen)-catalyzed hydrolytic kinetic resolution of a two-stereocentered anti-azido epoxide

Tetrahedron Asymmetry ◽

10.1016/j.tetasy.2016.10.013 ◽

2017 ◽

Vol 28 (1) ◽

pp. 162-165 ◽

Cited By ~ 3

Author(s):

Rambabu N. Reddi ◽

Pragati K. Prasad ◽

Rupali G. Kalshetti ◽

Arumugam Sudalai

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution

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ChemInform Abstract: An Enantioselective Synthesis of (R)-2-Amino-1-hydroxyethylphosphonic Acid (III) by Hydrolytic Kinetic Resolution of (.+-.)-Diethyl Oxiranephosphonate.

ChemInform ◽

10.1002/chin.199944221 ◽

2010 ◽

Vol 30 (44) ◽

pp. no-no

Author(s):

Peter B. Wyatt ◽

Peter Blakskjaer

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution

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Enantioselective synthesis of tarchonanthuslactone via iterative hydrolytic kinetic resolution

Tetrahedron Letters ◽

10.1016/j.tetlet.2005.07.056 ◽

2005 ◽

Vol 46 (38) ◽

pp. 6571-6573 ◽

Cited By ~ 28

Author(s):

Priti Gupta ◽

S. Vasudeva Naidu ◽

Pradeep Kumar

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution

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A facile enantioselective synthesis of enantiomerically pure (R)-phenoxybenzamine hydrochloride using the hydrolytic kinetic resolution method

Tetrahedron Asymmetry ◽

10.1016/j.tetasy.2010.11.011 ◽

2010 ◽

Vol 21 (23) ◽

pp. 2825-2829 ◽

Cited By ~ 11

Author(s):

Milind D. Nikalje ◽

Murugesan Sasikumar ◽

Murugan Muthukrishnan

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Resolution Method ◽

Enantiomerically Pure ◽

Hydrolytic Kinetic Resolution

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A new and efficient enantioselective synthesis of both enantiomers of the calcium channel blocker bepridil

New Journal of Chemistry ◽

10.1039/c6nj02928k ◽

2017 ◽

Vol 41 (2) ◽

pp. 824-829 ◽

Cited By ~ 4

Author(s):

Mohammad Mujahid ◽

Jambu Subramanian ◽

Viswanadh Nalla ◽

Murugesan Sasikumar ◽

Sunita Sharad Kunte ◽

...

Keyword(s):

Calcium Channel ◽

Calcium Channel Blocker ◽

Kinetic Resolution ◽

Channel Blocker ◽

Enantioselective Synthesis ◽

Mitsunobu Reaction ◽

Hydrolytic Kinetic Resolution ◽

Key Steps

We report a simple enantioselective synthesis of bepridil enantiomers employing hydrolytic kinetic resolution and the Mitsunobu reaction as key steps.

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An enantioselective synthesis of (R)-2-amino-1-hydroxyethylphosphonic acid by hydrolytic kinetic resolution of (±)-diethyl oxiranephosphonate

Tetrahedron Letters ◽

10.1016/s0040-4039(99)01259-9 ◽

1999 ◽

Vol 40 (35) ◽

pp. 6481-6483 ◽

Cited By ~ 16

Author(s):

Peter B. Wyatt ◽

Peter Blakskjær

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution

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First Enantioselective Synthesis of Surinamensinol B and a Non-Natural Polysphorin Analogue by a Two-Stereocentered Hydrolytic Kinetic Resolution

European Journal of Organic Chemistry ◽

10.1002/ejoc.201501009 ◽

2015 ◽

Vol 2015 (33) ◽

pp. 7344-7351 ◽

Cited By ~ 6

Author(s):

Komal G. Lalwani ◽

Arumugam Sudalai

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution

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A short enantioselective synthesis of ephedrine, amphetamine and their analogues via two stereocentered Co(III)-catalyzed hydrolytic kinetic resolution of racemic syn-benzyloxy epoxide

Tetrahedron Letters ◽

10.1016/j.tetlet.2015.10.010 ◽

2015 ◽

Vol 56 (46) ◽

pp. 6488-6490 ◽

Cited By ~ 1

Author(s):

Komal G. Lalwani ◽

Arumugam Sudalai

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution

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A practical enantioselective synthesis of massoialactone via hydrolytic kinetic resolution

Tetrahedron Letters ◽

10.1016/j.tetlet.2003.11.032 ◽

2004 ◽

Vol 45 (4) ◽

pp. 849-851 ◽

Cited By ~ 62

Author(s):

Priti Gupta ◽

S. Vasudeva Naidu ◽

Pradeep Kumar

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Hydrolytic Kinetic Resolution

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