scholarly journals The role of the right hemisphere in metaphor comprehension: A meta-analysis of functional magnetic resonance imaging studies

2012 ◽  
Vol 35 (1) ◽  
pp. 107-122 ◽  
Author(s):  
Jie Yang
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Right Hemisphere ◽  
Meta Analysis ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Imaging Studies ◽  
Metaphor Comprehension ◽  
The Right

scholarly journals Language activation in monozygotic twins discordant for schizophrenia

2004 ◽  
Vol 184 (2) ◽  
pp. 128-135 ◽  
Author(s):  
Iris E. C. Sommer ◽  
Nick F. Ramsey ◽  
René C. W. Mandl ◽  
Clarine J. Van Oel ◽  
René S. Kahn
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Right Hemisphere ◽  
Monozygotic Twins ◽  
Monozygotic Twin ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Language Activation ◽  
The Right ◽  
Discordant Twin

BackgroundIn previous functional magnetic resonance imaging (fMRI) studies, participants with schizophrenia showed decreased language lateralisation, resulting from increased activation of the right hemisphere compared with controls.AimTo determine whether decreased lateralisation and increased right cerebral language activation constitute genetic predispositions for schizophrenia.MethodLanguage activation was measured using fMRI in 12 right-handed monozygotic twin pairs discordant for schizophrenia and 12 healthy right-handed monozygotic twin pairs who were matched for gender, age and education.ResultsLanguage lateralisation was decreased in discordant twin pairs compared with the healthy twin pairs. The groups did not differ in activation of the language-related areas of the left hemisphere, but language-related activation in the right hemisphere was significantly higher in the discordant twin pairs than in the healthy pairs. Within the discordant twin pairs, language lateralisation was not significantly different between patients with schizophrenia and their co-twins.ConclusionsDecreased language lateralisation may constitute a genetic predisposition for schizophrenia.

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