The Role of the Right Hemisphere for Processing of Social Interactions in Normal Adults Using Functional Magnetic Resonance Imaging

2011 ◽  
Vol 64 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Margaret Semrud-Clikeman ◽  
Jodene Goldenring Fine ◽  
David C. Zhu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Social Interactions ◽  
Right Hemisphere ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
The Right ◽  
Normal Adults

scholarly journals Event-Related Functional Magnetic Resonance Imaging Study of the Extrastriate Cortex Response to a Categorically Ambiguous Stimulus Primed by Letters and Familiar Geometric Figures

2001 ◽  
Vol 21 (11) ◽  
pp. 1330-1341 ◽  
Author(s):  
Hélène Gros ◽  
Kader Boulanouar ◽  
Gérard Viallard ◽  
Emmanuelle Cassol ◽  
Pierre Celsis
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Right Hemisphere ◽  
Extrastriate Cortex ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Ambiguous Stimulus ◽  
Form Processing ◽  
Geometric Figures

Functional neuroimaging studies have suggested a specific role of the extrastriate cortex in letter string and visual word form processing. However, this region has been shown to be involved in object recognition and its specificity for the processing of linguistic stimuli may be questioned. The authors used an event-related functional magnetic resonance imaging design with category priming to record the response elicited by the passive viewing of single letters, geometric figures, and of the categorically ambiguous stimulus “O” that pertains to both sets of familiar symbols. Bilateral activations in the extrastriate cortex were found, with a left predominance particularly pronounced for the ambiguous stimulus. Individual analysis of spatial extent and signal intensity showed a priming × stimulus × hemisphere interaction. When primed by the congruous categoric set, a bilateral decrease in activation was observed for letters and geometric figures. The ambiguous stimulus behaved as a letter for the left hemisphere, with decreased activation when primed by letters, whereas in the right hemisphere, an adaptation effect occurred when primed by geometric figures. These priming effects suggest that, for the ambiguous stimulus, letter processing was systematically involved in the left extrastriate cortex. The current results support the existence of a neural substrate for the abstract category of letters.

scholarly journals Resting-State Functional Magnetic Resonance Imaging and Functional Connectivity Density Mapping in Patients With Optic Neuritis

2021 ◽  
Vol 15 ◽  
Author(s):  
Ke Song ◽  
Yong Wang ◽  
Mei-Xia Ren ◽  
Jiao Li ◽  
Ting Su ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Connectivity ◽  
Functional Magnetic Resonance Imaging ◽  
Optic Neuritis ◽  
Resting State ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Functional Connectivity Density ◽  
The Right

Background: Using resting-state functional connectivity (rsFC), we investigated alternations in spontaneous brain activities reflected by functional connectivity density (FCD) in patients with optic neuritis (ON).Methods: We enrolled 28 patients with ON (18 males, 10 females) and 24 healthy controls (HCs; 16 males, 8 females). All subjects underwent functional magnetic resonance imaging (fMRI) in a quiet state to determine the values of rsFC, long-range FCD (longFCD), and short-range FCD (IFCD). Receiver operating characteristic (ROC) curves were generated to distinguish patients from HCs.Results: The ON group exhibited obviously lower longFCD values in the left inferior frontal gyrus triangle, the right precuneus and the right anterior cingulate, and paracingulate gyri/median cingulate and paracingulate gyri. The left median cingulate and paracingulate gyri and supplementary motor area (SMA) were also significantly lower. Obviously reduced IFCD values were observed in the left middle temporal gyrus/angular gyrus/SMA and right cuneus/SMA compared with HCs.Conclusion: Abnormal neural activities were found in specific brain regions in patients with ON. Specifically, they showed significant changes in rsFC, longFCD, and IFCD values. These may be useful to identify the specific mechanism of change in brain function in ON.

scholarly journals Cerebral Functional Magnetic Resonance Imaging Activation Modulated by a Single Dose of the Monoamine Neurotransmission Enhancers Fluoxetine and Fenozolone during Hand Sensorimotor Tasks

1999 ◽  
Vol 19 (12) ◽  
pp. 1365-1375 ◽  
Author(s):  
Isabelle Loubinoux ◽  
Keder Boulanouar ◽  
Jean-Philippe Ranjeva ◽  
Christophe Carel ◽  
Isabelle Berry ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Single Dose ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Motor Activity ◽  
Healthy Subjects ◽  
Drug Effects ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging

Fluoxetine inhibits the reuptake of serotonin, and dextroamphetamine enhances presynaptic release of monoamines. Although the excitatory effect of both noradrenaline and dopamine on motor behavior generally is accepted, the role of serotonin on motor output is under debate. In the current investigation, the authors evidenced a putative role of monoamines and, more specifically, of serotonin in the regulation of cerebral motor activity in healthy subjects. The effects on cerebral motor activity of a single dose of fluoxetine (20 mg), an inhibitor of serotonin reuptake, and fenozolone (20 mg/50 kg), an amphetamine-like drug, were assessed by functional magnetic resonance imaging. Subjects performed sensorimotor tasks with the right hand. Functional magnetic resonance imaging studies were performed in two sessions on two different days. The first session, with two scan experiments separated by 5 hours without any drug administration, served as time-effect control. A second, similar session but with drug administration after the first scan assessed drug effects. A large increase in evoked signal intensity occurred in the ipsilateral cerebellum, and a parallel, large reduction occurred in primary and secondary motor cortices (P < 10–3). These results are consistent with the known effects of habituation. Both drugs elicited comparable effects, that is, a more focused activation in the contralateral sensorimotor area, a greater involvement of posterior supplementary motor area, and a widespread decrease of bilateral cerebellar activation (P < 10–3). The authors demonstrated for the first time that cerebral motor activity can be modulated by a single dose of fluoxetine or fenozolone in healthy subjects. Drug effects demonstrated a direct or indirect involvement of monoamines and serotonin in the facilitation of cerebral motor activity.

scholarly journals Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging

2006 ◽  
Vol 189 (6) ◽  
pp. 560-561 ◽  
Author(s):  
Therese Van Amelsvoort ◽  
Nicole Schmitz ◽  
Eileen Daly ◽  
Quinton Deeley ◽  
Hugo Critchley ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Emotional Processing ◽  
Brain Regions ◽  
Functional Neuroanatomy ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
The Right ◽  
Velo Cardio Facial Syndrome

SummaryWe studied the functional neuroanatomy of social behaviour in velo-cardio-facial syndrome (VCFS) using a facial emotional processing task and functional magnetic resonance imaging in adults with this syndrome and controls matched for age and IQ. The VCFS group had less activation in the right insula and frontal brain regions and more activation in occipital regions. Genetically determined abnormalities in pathways including those involved in emotional processing may underlie deficits in social cognition in people with VCFS.

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