Cognitive, psychiatric and motor response to galantamine in Parkinson's disease with dementia

2003 ◽  
Vol 18 (10) ◽  
pp. 937-941 ◽  
Author(s):  
D. Aarsland ◽  
M. Hutchinson ◽  
J. P. Larsen
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Response ◽  
Parkinson’S Disease With Dementia

Correlations between gray matter reductions and cognitive deficits in dementia with Lewy Bodies and Parkinson's disease with dementia

2009 ◽  
Vol 24 (12) ◽  
pp. 1740-1746 ◽  
Author(s):  
Cristina Sanchez-Castaneda ◽  
Ramon Rene ◽  
Blanca Ramirez-Ruiz ◽  
Jaume Campdelacreu ◽  
Jordi Gascon ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Gray Matter ◽  
Cognitive Deficits ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
Parkinson’S Disease With Dementia

scholarly journals Striatal and extrastriatal dysfunction in Parkinson’s disease with dementia: a 6‐[18F]fluoro‐l‐dopa PET study

Brain ◽  
2002 ◽  
Vol 125 (6) ◽  
pp. 1358-1365 ◽  
Author(s):  
Kengo Ito ◽  
Atsuko Nagano‐Saito ◽  
Takashi Kato ◽  
Yutaka Arahata ◽  
Akinori Nakamura ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Parkinson’S Disease With Dementia

P3-195: A TAU CLEAVAGE PRODUCT, ΔTAU314, IS INCREASED IN ALZHEIMER'S DISEASE AND PARKINSON'S DISEASE WITH DEMENTIA

2006 ◽  
Vol 14 (7S_Part_21) ◽  
pp. P1141-P1142
Author(s):  
Benjamin R. Smith ◽  
Kathryn Nelson ◽  
Peng Liu ◽  
Margaret E. Flanagan ◽  
Dirk Keene ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Parkinson’S Disease ◽  
Alzheimer's Disease ◽  
Parkinson's Disease ◽  
Cleavage Product ◽  
Parkinson’S Disease With Dementia ◽  
Tau Cleavage

The duration of the motor response to apomorphine boluses is conditioned by the length of a prior infusion in Parkinson's disease

2009 ◽  
Vol 24 (5) ◽  
pp. 762-766 ◽  
Author(s):  
Julia Vaamonde ◽  
José M. Flores ◽  
Roberto Weisser ◽  
Ramón Ibañez ◽  
José A. Obeso
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Response

THUR 117 The L-DOPA response in pathologically confirmed parkinson’s disease

2018 ◽  
Vol 89 (10) ◽  
pp. A12.4-A13
Author(s):  
Vanessa Pitz ◽  
Naveed Malek ◽  
Katherine A Grosset ◽  
Donald G Grosset
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Response ◽  
Standard Treatment ◽  
Disease Onset ◽  
Lewy Body Disease ◽  
Amyloid Angiopathy ◽  
Brain Pathology ◽  
Diffuse Lewy Body Disease ◽  
Available Information

Backgroundl-dopa is the standard treatment for Parkinson’s disease, but the response is variable.AimSystematic review of papers reporting the l-dopa response (motor response and/or complications) in pathologically confirmed Parkinson’s disease.Results467 cases of pathologically confirmed Parkinson’s were identified: 60.2% male, age at disease onset 63.3 years (SD 10.3), age at death 76.7 years (SD 7.8). Data on a graded l-dopa response were available in 411 cases (88.0% of 467). The motor response was excellent in 148/411 cases (36.0%), good in 179/411 (43.6%), moderate in 51/411 (12.4%) and poor/absent in 33/411 (8.0%). Data about motor complications were available for 161 patients: 71/161 (44.1%) had motor fluctuations and 89/161 (55.3%) had dyskinesia. Comorbid brain pathology was evaluated in 251/411 cases (61.1%), and was present in 148/251 (59.0%): cerebrovascular in 65/148 (43.9%), Alzheimer’s in 55/148 (37.2%), amyloid angiopathy in 18/148 (12.2%), and diffuse Lewy body disease in 10/148 (6.8%). Data linking the graded l-dopa response to comorbid pathologies were available in only 17 cases, of whom 8/17 (47.1%) had a good/excellent response.ConclusionThere is variation in the l-dopa response in pathologically confirmed Parkinson’s disease. The limited available information suggests a possible association of motor response to comorbid brain pathology.

Longitudinal study of the motor response to levodopa in Parkinson's disease

2006 ◽  
Vol 21 (12) ◽  
pp. 2116-2121 ◽  
Author(s):  
Benjamin G. Clissold ◽  
Craig D. McColl ◽  
Katrina R. Reardon ◽  
Mark Shiff ◽  
Peter A. Kempster
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Longitudinal Study ◽  
Motor Response
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