scholarly journals Regulation of Schwann cell function by the extracellular matrix

Glia ◽  
2008 ◽  
Vol 56 (14) ◽  
pp. 1498-1507 ◽  
Author(s):  
Michael A. Chernousov ◽  
Wei-Ming Yu ◽  
Zu-Lin Chen ◽  
David J. Carey ◽  
Sidney Strickland
Keyword(s):  
Extracellular Matrix ◽  
Schwann Cell ◽  
Cell Function

Role of Peripheral Nerve Extracellular Matrix in Schwann Cell Function and in Neurite Regeneration

1989 ◽  
Vol 11 (4-5) ◽  
pp. 348-360 ◽  
Author(s):  
Mary Bartlett Bunge ◽  
Richard P. Bunge ◽  
Naomi Kleitman ◽  
Andy C. Dean
Keyword(s):  
Extracellular Matrix ◽  
Schwann Cell ◽  
Peripheral Nerve ◽  
Cell Function

Macrophage depletion alters the blood–nerve barrier without affecting Schwann cell function after neural injury

2007 ◽  
Vol 85 (4) ◽  
pp. 766-777 ◽  
Author(s):  
Michael Gray ◽  
Winnie Palispis ◽  
Phillip G. Popovich ◽  
Nico van Rooijen ◽  
Ranjan Gupta
Keyword(s):  
Schwann Cell ◽  
Cell Function ◽  
Neural Injury ◽  
Macrophage Depletion

scholarly journals Vesicle-Mediated Control of Cell Function: The Role of Extracellular Matrix and Microenvironment

2018 ◽  
Vol 9 ◽  
Author(s):  
Gorjana Rackov ◽  
Noemi Garcia-Romero ◽  
Susana Esteban-Rubio ◽  
Josefa Carrión-Navarro ◽  
Cristobal Belda-Iniesta ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Cell Function

scholarly journals BIOENERGY ASPECTS OF FUNCTIONING OF VENOUS WALL COMPONENTS (DEMONSTRATION MATERIALS OF STUDENTS AND YOUNG SCIENTISTS)

2021 ◽  
Vol 1 (4) ◽  
Author(s):  
Mykhailo Lebedyuk ◽  
Vasily Bocharov ◽  
Veronika Bocharova ◽  
Ivanna Zarychniak ◽  
Аnastasia Kovalenok
Keyword(s):  
Extracellular Matrix ◽  
Cell Function ◽  
Vascular Wall ◽  
Vascular Component ◽  
The Subject ◽  
Wall Components ◽  
Venous Wall

The subject of the study – the wall of the venous vessels of the skin. The purpose of the work is to provide demonstration and text materials of the significance of bioenergetic mechanisms of vascular wall components. The vascular component is an integral part of the pathogenesis of most dermatoses. At the same time, the bioenergetic aspects of cell function and the extracellular matrix of the vascular wall, especially venous ones, are still insufficiently taken into account, as they are the most vulnerable to inflammatory dermatoses.Key words: vascular wall components, demonstration materials.

Precise Design Strategy Of  Smart Extracellular Matrix Based on CRISPR/Cas9 for Regulating Neural Stem Cell Function

2021 ◽  
Author(s):  
Yuanxin Zhai ◽  
Lingyan Yang ◽  
Wenlong Zheng ◽  
Quanwei Wang ◽  
Zhanchi Zhu ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Function ◽  
Design Strategy

scholarly journals Molecular profiling demonstrates modulation of immune cell function and matrix remodeling during luteal rescue†

2019 ◽  
Vol 100 (6) ◽  
pp. 1581-1596 ◽  
Author(s):  
Camilla K Hughes ◽  
Samar W Maalouf ◽  
Wan-Sheng Liu ◽  
Joy L Pate
Keyword(s):  
Extracellular Matrix ◽  
Corpus Luteum ◽  
Cell Function ◽  
Immune Cell ◽  
Cell Receptor ◽  
Cytokine Signaling ◽  
Matrix Remodeling ◽  
Proteomic Profiling ◽  
Interferon Tau ◽  
In Pregnancy

Abstract The corpus luteum (CL) is essential for maintenance of pregnancy in all mammals and luteal rescue, which occurs around day 16–19 in the cow, is necessary to maintain luteal progesterone production. Transcriptomic and proteomic profiling were performed to compare the day 17 bovine CL of the estrous cycle and pregnancy. Among mRNA and proteins measured, 140 differentially abundant mRNA and 24 differentially abundant proteins were identified. Pathway analysis was performed using four programs. Modulated pathways included T cell receptor signaling, vascular stability, cytokine signaling, and extracellular matrix remodeling. Two mRNA that were less in pregnancy were regulated by prostaglandin F2A in culture, while two mRNA that were greater in pregnancy were regulated by interferon tau. To identify mRNA that could be critical regulators of luteal fate, the mRNA that were differentially abundant during early pregnancy were compared to mRNA that were differentially abundant during luteal regression. Eight mRNA were common to both datasets, including mRNA related to regulation of steroidogenesis and gene transcription. A subset of differentially abundant mRNA and proteins, including those associated with extracellular matrix functions, were predicted targets of differentially abundant microRNA (miRNA). Integration of miRNA and protein data, using miRPath, revealed pathways such as extracellular matrix–receptor interactions, abundance of glutathione, and cellular metabolism and energy balance. Overall, this study has provided a comprehensive profile of molecular changes in the corpus luteum during maternal recognition of pregnancy and has indicated that some of these functions may be miRNA-regulated.

scholarly journals Integrins as architects of cell behavior

2016 ◽  
Vol 27 (19) ◽  
pp. 2885-2888 ◽  
Author(s):  
Charles H. Streuli
Keyword(s):  
Extracellular Matrix ◽  
Mammary Gland ◽  
Cell Surface ◽  
Cell Function ◽  
External Environment ◽  
Cell Behavior ◽  
Cell Surface Receptors ◽  
Surface Receptors ◽  
Mammary Gland Differentiation

Integrins are cell surface receptors that bind cells to their physical external environment, linking the extracellular matrix to cell function. They are essential in the biology of all animals. In the late 1980s, we discovered that integrins are required for the ability of breast epithelia to do what they are programmed to do, which is to differentiate and make milk. Since then, integrins have been shown to control most other aspects of phenotype: to stay alive, to divide, and to move about. Integrins also provide part of the mechanism that allows cells to form tissues. Here I discuss how we discovered that integrins control mammary gland differentiation and explore the role of integrins as central architects of other aspects of cell behavior.

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