Responses and signaling pathways in human optic nerve head astrocytes exposed to hydrostatic pressure in vitro

Glia ◽  
2004 ◽  
Vol 45 (4) ◽  
pp. 364-377 ◽  
Author(s):  
Mercedes Salvador-Silva ◽  
Shun Aoi ◽  
Amy Parker ◽  
Ping Yang ◽  
Paula Pecen ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Hydrostatic Pressure ◽  
Signaling Pathways ◽  
Optic Nerve Head ◽  
Human Optic Nerve

scholarly journals Microvascular Density Is Associated With Retinal Ganglion Cell Axonal Volume in the Laminar Compartments of the Human Optic Nerve Head

2018 ◽  
Vol 59 (3) ◽  
pp. 1562 ◽  
Author(s):  
Min H. Kang ◽  
Mengchen Suo ◽  
Chandrakumar Balaratnasingam ◽  
Paula K. Yu ◽  
William H. Morgan ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Nerve Head ◽  
Microvascular Density ◽  
Retinal Ganglion ◽  
Human Optic Nerve

In vitro evaluation of reactive astrocyte migration, a component of tissue remodeling in glaucomatous optic nerve head

Glia ◽  
2001 ◽  
Vol 34 (3) ◽  
pp. 178-189 ◽  
Author(s):  
G�lg�n Tezel ◽  
M. Rosario Hernandez ◽  
Martin B. Wax
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Tissue Remodeling ◽  
Reactive Astrocyte ◽  
In Vitro Evaluation

Variations in the Blood Flow of the Human Optic Nerve Head

1997 ◽  
Vol 7 (4) ◽  
pp. 364-369 ◽  
Author(s):  
R. Osuský ◽  
A. Schoetzau ◽  
J. Flammer
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Continuous Measurement ◽  
The Body ◽  
Flow Volume ◽  
Frequency Range ◽  
Flow Fluctuations ◽  
Human Optic Nerve ◽  
Doppler Flowmeter

Blood flow in various tissues of the body shows spontaneous variations. The purpose of this study was to analyze variations over time in the blood flow of the optic nerve head. Blood flow was measured by the laser Doppler flowmeter (LDF) in 12 healthy volunteers, and analyzed by spectral Fourier analysis. The LDF technique allows continuous measurement of flow, volume, and velocity in the microcirculation of the optic nerve head. We found variations expressed in cycles per minute (c/min) at frequencies characteristic of vasomotion (<10 c/min) of breathing, and of cardiac pulsation. Oscillations at frequency <10 c/min predominated in volume in all subjects and in flow in all but one. Variations in velocity of 60-90 c/min were identified in 10 of the 12 volunters. Oscillations in the range of breathing frequency made the smallest contribution to changes in blood flow. Fluctuations in the frequency range of 5 c/min and lower were observed most frequently, and the majority of subjects showed fluctuations of several frequencies. Our results provide evidence that blood flow in the human optic nerve head presents some characteristics already known from the general physiology of the microcirculation.

Acute effects of cigarette smoking on tissue circulation in human optic nerve head and choroid-retina

Ophthalmology ◽  
1999 ◽  
Vol 106 (3) ◽  
pp. 564-569 ◽  
Author(s):  
Yasuhiro Tamaki ◽  
Makoto Araie ◽  
Miyuki Nagahara ◽  
Ken Tomita
Keyword(s):  
Optic Nerve ◽  
Cigarette Smoking ◽  
Optic Nerve Head ◽  
Acute Effects ◽  
Human Optic Nerve ◽  
Tissue Circulation

Reproducibility of Laser Doppler Flowmetry in the Human Optic Nerve Head

1997 ◽  
Vol 6 (4) ◽  
pp. 212???216 ◽  
Author(s):  
Karen M. Joos ◽  
Lutz E. Pillunat ◽  
Robert W. Knighton ◽  
Douglas R. Anderson ◽  
William J. Feuer
Keyword(s):  
Optic Nerve ◽  
Laser Doppler Flowmetry ◽  
Optic Nerve Head ◽  
Laser Doppler ◽  
Doppler Flowmetry ◽  
Human Optic Nerve
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