scholarly journals Differential copy number aberrations in novel candidate genes associated with progression from in situ to invasive ductal carcinoma of the breast

2012 ◽  
Vol 51 (12) ◽  
pp. 1067-1078 ◽  
Author(s):  
Shaoxi Liao ◽  
Mohamed M. Desouki ◽  
Daniel P. Gaile ◽  
Lori Shepherd ◽  
Norma J. Nowak ◽  
...  
Keyword(s):  
Candidate Genes ◽  
Invasive Ductal Carcinoma ◽  
Copy Number ◽  
Ductal Carcinoma ◽  
Carcinoma Of The Breast ◽  
Copy Number Aberrations

Immunohistochemical expression of E-cadherin in sclerosing adenosis, ductal carcinoma in situ and invasive ductal carcinoma of the breast

2009 ◽  
pp. NA-NA
Author(s):  
Gil Facina ◽  
Pedro Vitor Lopes-Costa ◽  
Alesse Ribeiro Dos Santos ◽  
Rodrigo Jose De Vasconcelos-Valença ◽  
André Luis Pinho-Sobral ◽  
...  
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Immunohistochemical Expression ◽  
Carcinoma Of The Breast ◽  
Sclerosing Adenosis ◽  
E Cadherin

scholarly journals Accuracy of Digital Image Analysis (DIA) of Borderline Human Epidermal Growth Factor Receptor (HER2) Immunohistochemistry in Invasive Ductal Carcinoma

2020 ◽  
Vol 13 (9) ◽  
Author(s):  
Nema Mohamadian Roshan ◽  
Sepideh Salehabadi ◽  
Melika Kooshki Forooshani ◽  
Azin Nikoozadeh
Keyword(s):  
Image Analysis ◽  
Epidermal Growth Factor Receptor ◽  
In Situ Hybridization ◽  
Invasive Ductal Carcinoma ◽  
Digital Image Analysis ◽  
Ductal Carcinoma ◽  
Growth Factor Receptor ◽  
Carcinoma Of The Breast ◽  
Epidermal Growth

Background: Digital image analysis (DIA), used to extract information from pathology slides, provides better precision and no limitation regarding different interpretations by observers. Objectives: The present study aimed at evaluating the accuracy of DIA in the interpretation of borderline (2+) human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) slides of invasive ductal carcinoma of the breast. Methods: Sixty pathology samples with invasive ductal carcinoma of the breast were extracted based on HER2 (2+) and their fluorescence in situ hybridization (FISH), and chromogenic in situ hybridization (CISH) responses (as reference standard). The slides were digitized and, then, two pathologists examined the slides and documented diagnosis. DIA was performed by a free web application. Results: Totally, 307 digital images with 298 megabytes volume were extracted. The accuracy, sensitivity, and specificity values of DIA were 86 %, 46.1 %, and 97.8 %, respectively, with 8 false-negative cases. There was moderate agreement between the pathologist 1 (kappa = 0.42) and pathologist 2 (kappa = 0.41) with DIA. Conclusions: DIA had good accuracy and could be used for the interpretation of borderline HER2 IHC method in invasive ductal carcinoma.

scholarly journals p53 Overexpression is a Predictor of Local Recurrence After Treatment for Both in situ and Invasive Ductal Carcinoma of the Breast

2007 ◽  
Vol 140 (1) ◽  
pp. 109-114 ◽  
Author(s):  
Marnix A. de Roos ◽  
Geertruida H. de Bock ◽  
Jaap de Vries ◽  
Bert van der Vegt ◽  
Jelle Wesseling
Keyword(s):  
Local Recurrence ◽  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Carcinoma Of The Breast ◽  
P53 Overexpression

20q13.2 Amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast

1999 ◽  
Vol 435 (5) ◽  
pp. 469-472 ◽  
Author(s):  
M. Werner ◽  
Anita Mattis ◽  
Michaela Aubele ◽  
Margaret Cummings ◽  
Horst Zitzelsberger ◽  
...  
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Carcinoma Of The Breast
Sign in / Sign up

Export Citation Format

Share Document