Enantioseparation of chiral allenic acids by micellar electrokinetic chromatography with cyclodextrins as chiral selector

2005 ◽  
Vol 26 (4-5) ◽  
pp. 1001-1006 ◽  
Author(s):  
Zhaoyan Wang ◽  
Zhongmei Tang ◽  
Zhenhua Gu ◽  
Zhide Hu ◽  
Shengming Ma ◽  
...  
Keyword(s):  
Micellar Electrokinetic Chromatography ◽  
Chiral Selector ◽  
Electrokinetic Chromatography

PolysodiumN-Undecanoyl-l-leucylvalinate:  A Versatile Chiral Selector for Micellar Electrokinetic Chromatography

2003 ◽  
Vol 75 (3) ◽  
pp. 379-387 ◽  
Author(s):  
Shahab A. Shamsi ◽  
Bertha C. Valle ◽  
Fereshteh Billiot ◽  
Isiah M. Warner
Keyword(s):  
Micellar Electrokinetic Chromatography ◽  
Chiral Selector ◽  
Electrokinetic Chromatography

scholarly journals Enantioseparation of Penconazole, Myclobutanil and Triadimefon by Cyclodextrin-Modified Micellar Electrokinetic Chromatography

2014 ◽  
Vol 4 (2) ◽  
Author(s):  
Wan Aini Wan Ibrahim ◽  
Dadan Hermawan ◽  
M. Marsin Sanagi
Keyword(s):  
Chiral Separation ◽  
Micellar Electrokinetic Chromatography ◽  
Chiral Selector ◽  
Optimal Concentration ◽  
Acidic Condition ◽  
Analysis Time ◽  
Electrokinetic Chromatography ◽  
Triazole Fungicides ◽  
Separation Of Enantiomers

Simultaneous enantioseparation of three chiral triazole fungicides i.e. penconazole, myclobutanil and triadimefon bycyclodextrin-modified micellar electrokinetic chromatography (CD-MEKC) under acidic condition was investigated withdifferent HP--CD concentrations as chiral selector. The three triazole fungicides have an asymmetrically substitutedcarbon atom respectively, and they all contain two enantiomers. In order to achieve the best enantioresolution of thesetriazole fungicides, the HP--CD concentration range was optimized from 0 to 40 mM in 10 mM increment. The resultsindicate that separation of enantiomers was not achieved with concentration range of HP--CD from 0 to 20 mM.Simultaneous enantioseparation was successfully achived at 30 mM and 40 mM HP--CD concentration in 25 mMphosphate buffer (pH 3.0) solution that containing 50 mM SDS, 10% methanol and 5% acetonitrile. However,enantioresolution decreased for myclobutanil and triadimefon enantiomers with HP--CD concentration greater than 30mM. In addition, an increase in the concentration of HP--CD caused a significant increase in the analysis time. In light ofthese aspects, the optimal concentration for HP--CD was decided to be 30 mM for the simultaneous chiral separation ofthe three triazole fungicides with resolutions (Rs) between enantiomers for penconazole, Rs = 0.81; myclobutanil, Rs = 1.14;triadimefon, Rs = 2.09; peak efficiencies (N) greater than 108 000 for all stereoisomers and analysis time of less than 15min.

Determination of Imipenem and Cilastatin in Medicinal Products by Micellar Electrokinetic Chromatography

2017 ◽  
Vol 13 (2) ◽  
pp. 158-166 ◽  
Author(s):  
Tyski Stefan ◽  
Gruba Ewa ◽  
Bukowska Bozena ◽  
Michalska Katarzyna ◽  
Karpiuk Izabela
Keyword(s):  
Micellar Electrokinetic Chromatography ◽  
Electrokinetic Chromatography ◽  
Medicinal Products

Quantitative Analysis of Duloxetine and 1-Naphthol by Capillary Micellar Electrokinetic Chromatography

2011 ◽  
Vol 7 (3) ◽  
pp. 184-193 ◽  
Author(s):  
Nathalie R. Wingert ◽  
Aline B. Barth ◽  
Patricia Gomes ◽  
Elfrides E. S. Shapoval ◽  
Martin Steppe
Keyword(s):  
Quantitative Analysis ◽  
Micellar Electrokinetic Chromatography ◽  
Electrokinetic Chromatography
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